2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. TRPM8 agonist WS-3

TRPM8 agonist WS-3 

Cat. No.: HY-W014325 Purity: 99.35%
COA Handling Instructions

TRPM8 agonist WS-3 is an agonist of TRPM8 with an EC50 of 3.7 μM.

For research use only. We do not sell to patients.

TRPM8 agonist WS-3 Chemical Structure

TRPM8 agonist WS-3 Chemical Structure

CAS No. : 39711-79-0

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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Solid
500 mg USD 50 In-stock
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

TRPM8 agonist WS-3 Related Antibodies

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Description

TRPM8 agonist WS-3 is an agonist of TRPM8 with an EC50 of 3.7 μM.

IC50 & Target

EC50: 3.7 μM (TRPM8)[1]
Molecular Weight

211.34

Appearance

Solid

Formula

C13H25NO
CAS No.
SMILES

CC(C)C1CCC(C)CC1C(NCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (473.17 mM)

H2O : 1 mg/mL (4.73 mM; ultrasonic and heat to 60°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7317 mL 23.6586 mL 47.3171 mL
5 mM 0.9463 mL 4.7317 mL 9.4634 mL
10 mM 0.4732 mL 2.3659 mL 4.7317 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (11.83 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (11.83 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (11.83 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.35%

COA (248 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References
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TRPM8 agonist WS-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

TRPM8 agonist WS-339711-79-0TRP ChannelTransient receptor potential channelsInhibitorinhibitorinhibit

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