1. Apoptosis
  2. Apoptosis
    Caspase
    Bcl-2 Family
  3. Anticancer agent 63

Anticancer agent 63 

Cat. No.: HY-147504
Handling Instructions

Anticancer agent 63 (compound 3h) shows active in reducing the viability of different cancer cell lines, including SW480, HeLa, A549 and MCF-7, with IC50 values at 24 h of 4.9, 11.5, 9.4, and 3.4 μM, respectively. Anticancer agent 63 induce apoptosis in MCF-7 cells via down-regulating the expression of Bcl-2 and up-regulating the expression of IL-2 and Caspase-3. Anticancer agent 63 also shows antioxidant activity.

For research use only. We do not sell to patients.

Anticancer agent 63 Chemical Structure

Anticancer agent 63 Chemical Structure

CAS No. : 2529657-32-5

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Description

Anticancer agent 63 (compound 3h) shows active in reducing the viability of different cancer cell lines, including SW480, HeLa, A549 and MCF-7, with IC50 values at 24 h of 4.9, 11.5, 9.4, and 3.4 μM, respectively. Anticancer agent 63 induce apoptosis in MCF-7 cells via down-regulating the expression of Bcl-2 and up-regulating the expression of IL-2 and Caspase-3. Anticancer agent 63 also shows antioxidant activity[1].

IC50 & Target

Caspase-3

 

Bcl-2

 

Molecular Weight

394.33

Formula

C17H24F3NOSe

CAS No.
SMILES

CC(CC1=CC=C(C=C1)C(C(NCCC[Se]C(F)(F)F)=O)C)C

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Anticancer agent 63
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HY-147504
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