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Creatine monohydrate

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Based on 6 publication(s) in Google Scholar

Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.

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  • Pureté: 99.98%
  • CAS No.: 6020-87-7
  • Formule: C4H11N3O3
  • Masse moléculaire:149.15
  • Stockage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Creatine monohydrate Chemical Structure
    Creatine monohydrate Chemical Structure
  • Experimental Validation Results for Creatine monohydrate
  • Experimental Validation Results for Creatine monohydrate
  • Experimental Validation Results for Creatine monohydrate
  • Experimental Validation Results for Creatine monohydrate
  • Experimental Validation Results for Creatine monohydrate
  • Experimental Validation Results for Creatine monohydrate
CAS No.: 6020-87-7
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  • Creatine monohydrate Chemical Structure
    Creatine monohydrate Chemical Structure
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    Creatine monohydrate purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2025 Sep 9;122(36):e2426135122. [Abstract]

    Customer Validation
     SPR analysis showed Creatine (25 μM) binding to hCRT, with a dissociation constant (KD) of 3.2 μM.

  • 1/16

    Creatine monohydrate purchased from MedChemExpress. Usage Cited in: Cancer Immunol Res. 2025 Jun 4;13(6):939-956. [Abstract]

    Customer Validation
     Creatine (10, 100, and 1,000 µmol/L; 24 h) stimulates type I IFN induction via the cGAMP–cGAS–STING–IRF3 signaling axis. 2030-cGAMP was robustly induced in monocytes following Creatine treatment.

  • 1/16

    Creatine monohydrate purchased from MedChemExpress. Usage Cited in: Cancer Immunol Res. 2025 Jun 4;13(6):939-956. [Abstract]

    Customer Validation
     Examination of cGAS-STING downstream signaling in monocytes by flow cytometry revealed activation of the STING-TBK1-IRF3 signaling axis following Creatine (10, 100, and 1,000 µmol/L; 24 h) treatment.

  • 1/16

    Creatine monohydrate purchased from MedChemExpress. Usage Cited in: Cancer Immunol Res. 2025 Jun 4;13(6):939-956. [Abstract]

    Customer Validation
     Combination of LNP-Gsdme and Creatine (10.5 mg/mice; once daily; IT) synergistically suppresses tumor growth. Tumor growth curves, tumor images, and tumor weights of B16F10 and 4T1 tumor–bearing mice treated with LNP-Gsdme/GFP or combined with Creatine.

  • 1/16

    Creatine monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Sep 1;44(9):116139. [Abstract]

    Customer Validation
     The syngeneic mouse MC38 CRC model was utilized to examine how Creatine (oral gavage; 50 mg/mL; 400 μL/time; 3 times per week) supplementation, with or without the addition of anti-PD-1 antibody, affected tumor growth and survival. Tumor growth, tumor weights, and survival curves were recorded for the MC38 model mice given the different therapies. Combination therapy significantly suppressed tumor growth and prolonged survival of MC38 tumor-bearing immunocompetent C57BL/6 J mice compared to either single-agent or control-treated groups.

  • 1/16

    Creatine monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Sep 1;44(9):116139. [Abstract]

    Customer Validation
     Tumor growth curve and tumor weights of DLD1 xenografts after indicated treatment.To ascertain whether Creatine (oral gavage; 50 mg/mL; 400 μL/time; 3 times per week) exhibits an inhibitory effect on tumor progression, a DLD-1 xenograft model was established, and Creatine was found to remarkably inhibit tumor development.

  • Creatine monohydrate