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Cat. No.: HY-118421

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Nullscript

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Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid. Scriptaid is a representative HDAC inhibitor. Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC₅₀ value of 2.1 μM.

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Pureté: 98.18%
CAS No.: 300816-11-9
Formule: C₁₆H₁₄N₂O₄
Masse moléculaire:298.29

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Nullscript Chemical Structure

CAS No.: 300816-11-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid^[1]. Scriptaid is a representative HDAC inhibitor^[2]. Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC₅₀ value of 2.1 μM^[3].

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Chemical Information

CAS No. 300816-11-9
Appearance Solid
Masse moléculaire 298.29
Formule C₁₆H₁₄N₂O₄
Color Off-white to pink
SMILES

O=C(N(C1=O)CCCC(NO)=O)C2=CC=CC3=CC=CC1=C23
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Min Tong, et al. Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochem Pharmacol. 2006 Sep 14;72(6):701-9. [Content Brief]

[2]. Judith Clancy Keen, et al. A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. Breast Cancer Res Treat. 2003 [Content Brief]

[3]. Fumi Murakoshi, et al. Nullscript inhibits Cryptosporidium and Toxoplasma growth. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:159-166. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Nullscript

High-Throughput Bioactive Compound Library

Voir tous les produits spécifiques à Isoform Parasite

Voir tous les produits spécifiques à Isoform HDAC

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Nullscript Related Classifications

HY-118421 Related Classifications