TrimTAC1
TrimTAC1 is a TRIM21-based PROTAC targeting BRD4. TrimTAC1 selectively degrads NUP98FG-mEGFP-BRD4BD2 nuclear condensates. TrimTAC1 does not degrade soluble mEGFP-BRD4BD2 in A549 cells.
(Pink: BRD4 ligand (HY-13030); Blue: TRIM21 ligand (HY-169356); Black: linker (HY-W088456)).
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- CAS No.: 3095569-91-5
- Formule: C43H47ClN8O2S2
- Masse moléculaire:807.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Activité biologique
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BRD4 |
Chemical Information
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CAS No. 3095569-91-5
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Masse moléculaire 807.47
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Formule C43H47ClN8O2S2
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SMILES
O=C(NCCCN1CCN(CCCN2C(C=CC=C3)=C3SC4=C2C=C(C(C)=O)C=C4)CC1)C[C@H]5C6=NN=C(N6C7=C(C(C8=CC=C(C=C8)Cl)=N5)C(C)=C(S7)C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TrimTAC1 Related Classifications
HY-169355 Related Classifications
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