CAV1 - caveolin 1 Gene

Also Known as CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 857

About CAV1

Cytogenetic location: 7q31.2 Genomic coordinates (GRCh38): 7:116,525,009-116,561,185 (from NCBI)

This gene has 9 transcripts (splice variants), 207 orthologues, 2 paralogues and is associated with 8 phenotypes. Biased expression in fat (RPKM 322.1), lung (RPKM 308.8) and 13 other tissues.

Summary

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links Integrin subunits to the tyrosine kinase Fyn, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each Other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]

CAV1 Products (4)

mRNA	Protein	Name
NM_001172895.1	NP_001166366.1	caveolin-1 isoform beta
NM_001172896.2	NP_001166367.1	caveolin-1 isoform beta
NM_001172897.2	NP_001166368.1	caveolin-1 isoform beta
NM_001753.5	NP_001744.2	caveolin-1 isoform alpha

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables ATPase binding	IPI IPI: Inferred from physical interaction	24089527	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	20122998	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	25006397	GOA
enables inward rectifier potassium channel inhibitor activity	IDA IDA: Inferred from direct assay	18923542	GOA
enables nitric-oxide synthase binding	IPI IPI: Inferred from physical interaction	12852865	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10212252	GOA
enables protein kinase binding	IPI IPI: Inferred from physical interaction	25006397	GOA
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	24089527	GOA
enables signaling receptor binding	IPI IPI: Inferred from physical interaction	16890161	GOA
enables small GTPase binding	IPI IPI: Inferred from physical interaction	24625804	GOA
enables transmembrane transporter binding	IPI IPI: Inferred from physical interaction	18923542	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in T cell costimulation	IDA IDA: Inferred from direct assay	17287217	GOA
involved in apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	21382479	GOA
involved in canonical Wnt signaling pathway	IDA IDA: Inferred from direct assay	16890161	GOA
involved in caveola assembly	IGI IGI: Inferred from genetic interaction	25006397	GOA
involved in caveola assembly	IMP IMP: Inferred from mutant phenotype	12633858	GOA
involved in caveolin-mediated endocytosis	IDA IDA: Inferred from direct assay	19931615	GOA
involved in cellular response to exogenous dsRNA	IMP IMP: Inferred from mutant phenotype	25204797	GOA
involved in cellular response to hyperoxia	IMP IMP: Inferred from mutant phenotype	21382479	GOA
involved in cellular response to misfolded protein	IMP IMP: Inferred from mutant phenotype	24089527	GOA
involved in cellular response to starvation	IEP IEP: Inferred from expression pattern	15657086	GOA
involved in negative regulation of BMP signaling pathway	IDA IDA: Inferred from direct assay	15657086	GOA
involved in negative regulation of anoikis	IMP IMP: Inferred from mutant phenotype	22277751	GOA
involved in negative regulation of inward rectifier potassium channel activity	IMP IMP: Inferred from mutant phenotype	18923542	GOA
involved in negative regulation of peptidyl-serine phosphorylation	IDA IDA: Inferred from direct assay	18081315	GOA
involved in negative regulation of peptidyl-tyrosine autophosphorylation	IMP IMP: Inferred from mutant phenotype	25006397	GOA
involved in negative regulation of pinocytosis	IMP IMP: Inferred from mutant phenotype	23583380	GOA
involved in negative regulation of potassium ion transmembrane transport	IMP IMP: Inferred from mutant phenotype	18923542	GOA
involved in negative regulation of protein tyrosine kinase activity	IMP IMP: Inferred from mutant phenotype	25006397	GOA
involved in negative regulation of protein ubiquitination	IMP IMP: Inferred from mutant phenotype	22277751	GOA
involved in positive regulation of ERAD pathway	IMP IMP: Inferred from mutant phenotype	24089527	GOA
involved in positive regulation of canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	23319823	GOA
involved in positive regulation of cell adhesion molecule production	IMP IMP: Inferred from mutant phenotype	25204797	GOA
involved in positive regulation of cell migration	IMP IMP: Inferred from mutant phenotype	21109942	GOA
involved in positive regulation of cholesterol efflux	IDA IDA: Inferred from direct assay	24576892	GOA
involved in positive regulation of extrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	21382479	GOA
involved in positive regulation of intrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	21382479	GOA
involved in positive regulation of peptidyl-serine phosphorylation	IDA IDA: Inferred from direct assay	18081315	GOA
involved in positive regulation of protein ubiquitination	IMP IMP: Inferred from mutant phenotype	24089527	GOA
involved in positive regulation of toll-like receptor 3 signaling pathway	IMP IMP: Inferred from mutant phenotype	25204797	GOA
involved in receptor internalization	IDA IDA: Inferred from direct assay	25893292	GOA
involved in receptor internalization	IMP IMP: Inferred from mutant phenotype	16890161	GOA
involved in receptor-mediated endocytosis of virus by host cell	IGI IGI: Inferred from genetic interaction	21047970	GOA
involved in regulation of blood coagulation	IMP IMP: Inferred from mutant phenotype	17848177	GOA
involved in regulation of cytosolic calcium ion concentration	IDA IDA: Inferred from direct assay	19052258	GOA
involved in regulation of entry of bacterium into host cell	IDA IDA: Inferred from direct assay	24625804	GOA
involved in regulation of membrane repolarization during action potential	IMP IMP: Inferred from mutant phenotype	18923542	GOA
involved in regulation of ruffle assembly	IDA IDA: Inferred from direct assay	24625804	GOA
involved in response to bacterium	IDA IDA: Inferred from direct assay	24625804	GOA
acts upstream of or within response to estrogen	IDA IDA: Inferred from direct assay	12388746	GOA
acts upstream of or within response to progesterone	IDA IDA: Inferred from direct assay	12388746	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in Golgi membrane	IDA IDA: Inferred from direct assay	11294831	GOA
located in apical plasma membrane	IDA IDA: Inferred from direct assay	16904002	GOA
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	16904002	GOA
located in caveola	IDA IDA: Inferred from direct assay	15219854	GOA
located in cytoplasmic vesicle	IDA IDA: Inferred from direct assay	19931615	GOA
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	11294831	GOA
located in endosome	IDA IDA: Inferred from direct assay	20682791	GOA
colocalizes with focal adhesion	IDA IDA: Inferred from direct assay	12091389	GOA
located in membrane	IDA IDA: Inferred from direct assay	24625804	GOA
located in membrane raft	IDA IDA: Inferred from direct assay	11294831	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	19931615	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	23262137	GOA
part of protein-containing complex	IDA IDA: Inferred from direct assay	21822278	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CAV1 Protein Structure

Caveolin

0
100
178 a.a.

Protein Preferred Names	Protein Names
caveolin-1	caveolin 1, caveolae protein, 22kDa

CAV1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CAV1	Q03135	MCL1	Homo sapiens	Q07820	Anti Bait CoIP	22277751
Intra	CAV1	Q03135	RASA1	Homo sapiens	P20936	Pull Down	15504032
Intra	CAV1	Q03135	RASA1	Homo sapiens	P20936	Protein Array	20808760
Intra	CAV1	Q03135	SCP2	Homo sapiens	P22307	FRET	15182174
Intra	CAV1	Q03135	SCP2	Homo sapiens	P22307	Y2H	15182174
Intra	CAV1	Q03135	ID1	Homo sapiens	P41134	Anti Bait CoIP	17855368
Intra	CAV1	Q03135	ID1	Homo sapiens	P41134	Anti Tag CoIP	17855368
Intra	CAV1	Q03135	FAS	Homo sapiens	P25445-1	Anti Bait CoIP	20956295
Intra	CAV1	Q03135	VAV2	Homo sapiens	P52735-1	Anti Tag CoIP	20808760
Cross	CAV1	Q03135	P0DTD1-PRO_0000449624	SARS-CoV-2	P0DTD1-PRO_0000449624	Y2H Array	36217030
Intra	CAV1	Q03135	CAVIN1	Homo sapiens	Q6NZI2	Anti Tag CoIP	24013648
Intra	CAV1	Q03135	F2R	Homo sapiens	P25116	Anti Bait CoIP	20826780
Intra	CAV1	Q03135	EGFR	Homo sapiens	P00533	Anti Bait CoIP	22411794
Intra	CAV1	Q03135	EGFR	Homo sapiens	P00533	Ub Reconstruction	24658140
Intra	CAV1	Q03135	VAV2	Homo sapiens	P52735	Pull Down	20808760
Intra	CAV1	Q03135	CAVIN3	Homo sapiens	Q969G5	Anti Tag CoIP	24013648
Intra	CAV1	Q03135	CAVIN3	Homo sapiens	Q969G5	IF	19262564
Intra	CAV1	Q03135	RAC1	Homo sapiens	P63000	Pull Down	24625804
Intra	CAV1	Q03135	RAC1	Homo sapiens	P63000	Anti Tag CoIP	22614015
Intra	CAV1	Q03135	STK38	Homo sapiens	Q15208	Anti Tag CoIP	31980649
Intra	CAV1	Q03135	STK38	Homo sapiens	Q15208	Anti Bait CoIP	31980649
Intra	CAV1	Q03135	FAS	Homo sapiens	P25445	Anti Bait CoIP	21382479
Intra	CAV1	Q03135	BID	Homo sapiens	P55957	Anti Bait CoIP	21382479
Intra	CAV1	Q03135	CAV2	Homo sapiens	P51636	Anti Tag CoIP	24013648
Intra	CAV1	Q03135	CAV2	Homo sapiens	P51636	Anti Bait CoIP	10212252
Intra	CAV1	Q03135	CAV2	Homo sapiens	P51636	Anti Tag CoIP	33961781
Intra	CAV1	Q03135	TXNRD1	Homo sapiens	Q16881	Density Sedimentation	19820694
Intra	CAV1	Q03135	TXNRD1	Homo sapiens	Q16881	Pull Down	19820694
Intra	CAV1	Q03135	TXNRD1	Homo sapiens	Q16881	Anti Bait CoIP	19820694
Intra	CAV1	Q03135	KCNH2	Homo sapiens	Q12809	Y2H	18923542
Intra	CAV1	Q03135	CAVIN2	Homo sapiens	O95810	Anti Tag CoIP	24013648
Intra	CAV1	Q03135	PLCG1	Homo sapiens	P19174	Protein Array	20808760
Intra	CAV1	Q03135	PLCG1	Homo sapiens	P19174	Pull Down	20808760
Intra	CAV1	Q03135	CSNK1D	Homo sapiens	P48730-2	Y2H Array	32814053
Intra	CAV1	Q03135	CSNK1D	Homo sapiens	P48730-2	Y2H Pooling	32814053
Intra	CAV1	Q03135	CSNK1D	Homo sapiens	P48730-2	Validated Y2H	32814053
Intra	CAV1	Q03135	LRP6	Homo sapiens	O75581	IF	16890161
Intra	CAV1	Q03135	TRPC1	Homo sapiens	P48995	Anti Bait CoIP	19897728
Intra	CAV1	Q03135	PTPN1	Homo sapiens	P18031	CoIP	12176037
Intra	CAV1	Q03135	PTPN1	Homo sapiens	P18031	Density Sedimentation	12176037
Intra	CAV1	Q03135	PTPN1	Homo sapiens	P18031	Phosphatase Assay	16388599
Cross	CAV1	Q03135	Axin1	Rattus norvegicus	O70239	Anti Tag CoIP	16890161

Cross: Cross-species interaction Intra: Intraspecies interaction

CAV1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80053	Caveolin-1 Antibody (YA549)	WB, ICC/IF, IHC-P	Human, Mouse
HY-P82037	Caveolin-1 Antibody (YA1782)	WB, IHC-F, IHC-P, ICC/IF, IP	Human
HY-P82037A	Caveolin-1 Antibody (YA1782)(PBS only)	WB, IHC-F, IHC-P, ICC/IF, IP	Human
HY-P86337	Caveolin-1 Antibody (YA6029)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Lipodystrophy, Congenital Generalized, Type 3	Congenital Generalized Lipodystrophy Type 3 CGL3 Bscl3 Berardinelli-Seip Congenital Lipodystrophy Type 3 Berardinelli-Seip Congenital Lipodystrophy, Type 3 Lipodystrophy, Berardinelli-Seip Congenital, Type 3 Type 3 Berardinelli-Seip Congenital Lipodystrophy Congenital Generalized Lipodystrophy 3
Pulmonary Hypertension, Primary, 3	PPH3 Hypertension, Pulmonary, Primary, Type 3
Lipodystrophy, Familial Partial, Type 7	Partial Lipodystrophy, Congenital Cataracts, And Neurodegeneration Syndrome FPLD7 Lccns Partial Lipodystrophy, Congenital Cataracts, With Or Without Neurodegeneration Syndrome Lipodystrophy, Familial Partial, 7 Lipodystrophy, Partial, With Congenital Cataracts And Neurodegeneration
Heritable Pulmonary Arterial Hypertension	Fpah Familial Pulmonary Arterial Hypertension Hpah Hereditary Pulmonary Arterial Hypertension Familial Primary Pulmonary Hypertension
Congenital Generalized Lipodystrophy	Berardinelli-Seip Congenital Lipodystrophy Berardinelli-Seip Syndrome Brunzell Syndrome Bscl Generalized Lipodystrophy Lipodystrophy, Congenital Generalized Seip Syndrome Total Lipodystrophy Cgl Lipoatrophic Diabetes Lipodystrophy, Generalized, Congenital Familial Generalized Lipodystrophy Congenital Generalized Lipodystrophy Type 2 Lipoatrophic Diabetes Mellitus Familial Partial Lipodystrophy, Type 2
Diffuse Cutaneous Systemic Sclerosis	Diffuse Cutaneous Systemic Scleroderma Progressive Cutaneous Systemic Scleroderma Progressive Cutaneous Systemic Sclerosis Dcssc Diffuse Scleroderma
Limited Scleroderma	Limited Cutaneous Systemic Sclerosis Limited Systemic Sclerosis Systemic Sclerosis Sine Scleroderma Crest Syndrome Limited Cutaneous Systemic Scleroderma Scleroderma, Limited Systemic Sclerosis, Limited Progressive Systemic Sclerosis Sine Scleroderma Scleroderma, Sine Crest - [Calcinosis, Raynaud Phenomenon, Oesophageal Dysmotility, Sclerodactyly, And Telangiectasia] Syndrome Crst - [Calcinosis, Raynaud Phenomenon, Sclerodactyly And Telangiectasia] Syndrome
Berardinelli-Seip Congenital Lipodystrophy	Berardinelli-Seip Congenital Generalized Lipodystrophy Familial Generalized Lipodystrophy
Pulmonary Hypertension	Primary Pulmonary Hypertension Hypertension Pulmonary Hypertension, Pulmonary Hypertension, Pulmonary, Primary Idiopathic Pulmonary Hypertension Idiopathic Pulmonary Arterial Hypertension Pulmonary Htn - [Hypertension]
Lung Pleomorphic Carcinoma
Cholera	Vibrio Cholerae Infection Cholera - Vibrio Cholerae Cholera Due To Vibrio Cholerae Vibrio Cholerae Cholera Syndrome Asiatic Cholera Epidemic Cholera
Oncocytoma	Oxyphilic Adenoma Follicular Adenoma, Oxyphilic Cell Adenoma, Oxyphilic Hurthle Cell Tumor Oncocytic Neoplasm
Complete Generalized Lipodystrophy
Hepatopulmonary Syndrome
Lipodystrophy, Congenital Generalized, Type 2	Congenital Generalized Lipodystrophy Type 2 CGL2 Berardinelli-Seip Congenital Lipodystrophy Type 2 Berardinelli-Seip Syndrome Brunzell Syndrome Bscl2-Related Total Lipodystrophy And Acromegaloid Gigantism Berardinelli-Seip Congenital Lipodystrophy, Type 2 Seip Syndrome Berardinelli Syndrome Lipodystrophy, Total, And Acromegaloid Gigantism Lipoatrophic Diabetes, Congenital Lipodystrophy, Berardinelli-Seip Congenital, Type 2 Brunzell Syndrome, Bscl2-Related Congenital Lipoatrophic Diabetes Congenital Generalized Lipodystrophy 2 Lipoatrophic Diabetes Lipodystrophy Berardinelli Type Familial Generalized Lipodystrophy Lipoatrophic Diabetes Mellitus Familial Partial Lipodystrophy, Type 2
Li-Fraumeni Syndrome	Sarcoma Family Syndrome Of Li And Fraumeni Sbla Syndrome LFS Li-Fraumeni Familiar Cancer Susceptibility Syndrome Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome Lfs1 Li Fraumeni Syndrome Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome Lfl Sbla Syndrome Li-Fraumeni-Like Syndrome Li-Fraumeni Syndrome 1
Tetanus	Lockjaw Clostridial Tetanus Infection Due To Clostridium Tetani Lock-Jaw
Pulmonary Fibrosis	Fibrosis Of Lung
Malignant Hyperthermia	Anesthesia Related Hyperthermia Malignant Hyperpyrexia Due To Anesthesia Hyperpyrexia, Malignant Hyperthermia, Malignant Malignant Hyperpyrexia Mhs Malignant Fever
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Lipodystrophy, Congenital Generalized, Type 4	Congenital Generalized Lipodystrophy Type 4 CGL4 Berardinelli-Seip Congenital Lipodystrophy, Type 4, With Muscular Dystrophy Lipodystrophy, Berardinelli-Seip Congenital, Type 4, With Muscular Dystrophy Berardinelli-Seip Congenital Lipodystrophy Type 4 With Muscular Dystrophy Generalized Congenital Lipodystrophy With Myopathy Congenital Generalised Lipodystrophy Type 4 Generalised Congenital Lipodystrophy Type 4 Generalised Congenital Lipodystrophy With Myopathy Generalized Congenital Lipodystrophy Type 4 Gcl4 Congenital Generalized Lipodystrophy 4 Berardinelli-Seip Congenital Lipodystrophy Type 4
Retinal Cone Dystrophy 4	RCD4 Doid:0081023 Dystrophy, Retinal Cone, Type 4
Pulmonary Venoocclusive Disease	Pulmonary Veno-Occlusive Disease Obstructive Disease Of The Pulmonary Veins Pvod Isolated Pulmonary Venous Sclerosis Venous Form Of Primary Pulmonary Hypertension Pulmonary Venoocclusive Disease 1, Autosomal Dominant
Lipodystrophy, Familial Partial, Type 2	FPLD2 Lipoatrophic Diabetes Familial Partial Lipodystrophy Type 2 Familial Partial Lipodystrophy, Dunnigan Type Fpl2 Lipoatrophic Diabetes Mellitus Lipodystrophy, Familial Partial, Dunnigan Type Lipodystrophy, Familial, Of Limbs And Lower Trunk Lipodystrophy, Reverse Partial Familial Partial Lipodystrophy Dunnigan Type Dunnigan Syndrome Familial Lipodystrophy Of Limbs And Lower Trunk Reverse Partial Lipodystrophy Lipodystrophy, Familial Partial, 2 Generalized Lipoatrophy Associated With Diabetes, Hepatic Steatosis, Hypertrophic Cardiomyopathy And Leukomelanodermic Papules Lipodystrophy Familial Of Limbs And Lower Trunk Lipodystrophy Reverse Partial Diabetes Mellitus, Lipoatrophic Familial Partial Lipodystrophy, Type 2 Familial Generalized Lipodystrophy
Achalasia	Cardiospasm Achalasia Of Cardia Esophageal Achalasia Hypertensive Lower Esophageal Sphincter Idiopathic Achalasia Achalasia Cardia Idiopathic Achalasia Of Esophagus Primary Achalasia Achalasia Of Esophagus Lack Of Reflex Relaxation Of Lower Oesophageal Sphincter Aperistalsis Of The Oesophagus Achalasia Of Oesophagus Oesophageal Achalasia Achalasia Nos Cardia Spasm Cardia Achalasia Oesophageal Cardiospasm Oesophagus Achalasia Reflex Cardiospasm
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Colon Adenocarcinoma	Adenocarcinoma Of Colon Adenocarcinoma Of The Colon Colonic Adenocarcinoma
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Muscular Dystrophy	Muscular Dystrophies Congenital Md Congenital Muscular Dystrophy Cmd Mdc Dystrophy, Muscular Gower'S Muscular Dystrophy Progressive Musclular Dystrophy Pseudohypertrophic Atrophy Pseudohypertrophic Muscle Paralysis Pseudohypertrophic Muscular Atrophy Pseudohypertrophic Muscular Dystrophy Pseudohypertrophic Paralysis Pseudomuscular Hypertrophy
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Laryngotracheitis
Spermatogenic Failure 6	Globozoospermia SPGF6 Round-Headed Spermatozoa Acrosome Malformation Of Spermatozoa Spermatogenic Failure 9 Spermatozoa, Round-Headed Globozoospermia, Complete Globozoospermia, Total Mae Infertility Due To Round-Headed Spermatozoa Male Infertility Due To Globozoospermia Male Infertility Due To Round-Headed Spermatozoa Round-Headed Sperm Syndrome Spgf9 Teratozoospermia
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Glaucoma, Primary Open Angle	Glaucoma 1, Open Angle, E Primary Open Angle Glaucoma POAG Adult-Onset Primary Open Angle Glaucoma Chronic Simple Glaucoma GLC1E Primary Open Angle Glaucoma 1e Glaucoma, Open Angle, Primary
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Rippling Muscle Disease 2	Rippling Muscle Disease Rmd Lgmd1c RMD2 Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1c Muscular Dystrophy, Limb-Girdle, Type 1c Muscular Dystrophy, Limb-Girdle, Type 1c, Formerly Lgmd1c, Formerly Limb-Girdle Muscular Dystrophy Type 1c Limb-Girdle Muscular Dystrophy Due To Caveolin-3 Deficiency Muscular Dystrophy, Limb-Girdle, Type Ic Rippling Muscle Syndrome Limb-Girdle Muscular Dystrophy 1c Dystrophy, Muscular, Limb-Girdle, Type 1c Disease, Muscle, Rippling, Type 2 Rippling Muscle Disease 1
Glaucoma, Normal Tension	Low Tension Glaucoma Glaucoma, Normal Tension, Susceptibility To Normal Tension Glaucoma Ntg Glaucoma, Normal Pressure NPG Glaucoma, Normal Pressure, Susceptibility To Poag/Npg - [Normal Pressure Primary Open-Angle Glaucoma]
Amelogenesis Imperfecta, Type Ig	Enamel-Renal Syndrome Ers Amelogenesis Imperfecta Type 1g AI1G Enamel-Renal-Gingival Syndrome Amelogenesis Imperfecta And Gingival Fibromatosis Syndrome Aigfs Amelogenesis Imperfecta, Hypoplastic, With Nephrocalcinosis Amelogenesis Imperfecta Hypoplastic With Nephrocalcinosis Amelogenesis Imperfecta Type Ig Amelogenesis Imperfecta-Nephrocalcinosis Syndrome Amelogenesis Imperfecta 1g Hypoplastic Amelogenesis Imperfecta With Nephrocalcinosis Amelogenesis Imperfecta Nephrocalcinosis
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Rhabdomyosarcoma
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Brugada Syndrome 4	BRGDA4 Brugada Syndrome, Type 4
Isolated Elevated Serum Creatine Phosphokinase Levels	Elevated Serum Cpk Idiopathic Hyperckemia Isolated Hyperckemia Elevated Serum Creatine Phosphokinase H-Ck Idiopathic Persistent Elevation Of Serum Creatine Kinase
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Spinocerebellar Ataxia, X-Linked 3	Scax3 X-Linked Spinocerebellar Ataxia 3 X-Linked Ataxia-Deafness Syndrome X-Linked Spinocerebellar Ataxia Type 3 Ataxia-Deafness Syndrome, X-Linked Spinocerebellar Ataxia X-Linked Type 3 Ataxia-Deafness Syndrome X-Linked X-Linked Ataxia-Hearing Loss Syndrome Spinocerebellar Ataxia, X-Linked, 3
Spinocerebellar Ataxia, X-Linked 4	Scax4 X-Linked Spinocerebellar Ataxia 4 X-Linked Ataxia-Dementia Syndrome X-Linked Spinocerebellar Ataxia Type 4 Ataxia-Dementia Syndrome, X-Linked Spinocerebellar Ataxia X-Linked Type 4 Ataxia-Dementia Syndrome X-Linked Spinocerebellar Ataxia, X-Linked, 4
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Moyamoya Disease 1	Moyamoya Disease Spontaneous Occlusion Of The Circle Of Willis Mymy Progressive Intracranial Arterial Occlusion Moyamoya Syndrome MYMY1 Cerebrovascular Moyamoya Disease Moya-Moya Disease Progressive Intracranial Occlusive Arteropathy Idiopathic Moyamoya Disease
Diabetes Mellitus	Diabetes
Amelogenesis Imperfecta	Ai Congenital Enamel Hypoplasia Al - [Amelogenesis Imperfecta]
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset Obesity , Susceptibility To BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Congenital Stationary Night Blindness	Night Blindness, Congenital Stationary Congenital Essential Nyctalopia Oguchi Disease Blindness, Night, Stationary, Congenital
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Noonan Syndrome 1	Noonan Syndrome NS1 Male Turner Syndrome Female Pseudo-Turner Syndrome Turner Phenotype With Normal Karyotype Noonan Syndrome With Pigmented Villonodular Synovitis Turner'S Phenotype, Karyotype Normal Familial Turner Syndrome Noonan'S Syndrome Noonan-Ehmke Syndrome Ns Pseudo-Ullrich-Turner Syndrome Turner Syndrome In Female With X Chromosome Turner-Like Syndrome Ullrich-Noonan Syndrome Noonan-Like/Multiple Giant Cell Lesion Syndrome Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions Pterygium Colli Syndrome Noonan Syndrome, Type 1 Turner Syndrome, Male
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B1090	Cinnarizine	Inhibitor	99.56%	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-112499	Menaquinone-7	Activator	98.51%	Phase 2
HY-112499R	Menaquinone-7 (Standard)		98.27%	Phase 2

Pre-clinical Phase

Bioactive Molecules (32)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-134542	CaV1.3 antagonist-1	Antagonist	98.38%	Unkown
HY-N2488	Demethylsuberosin	Inhibitor	99.71%	Unkown
HY-RS01986	CAV1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-B1752	Quinpirole		98.95%	Unkown
HY-106454	N-Desalkylflurazepam	Inhibitor	99.95%	Unkown
HY-RS17533	Cav1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-Z15823	(R)-Verapamil		98.97%	Unkown
HY-118202	(-)-Gallopamil	Inhibitor	/	Unkown
HY-118202A	(-)-Gallopamil hydrochloride	Inhibitor	/	Unkown
HY-126336	HM12	Inhibitor	/	Unkown
HY-146173	KCa1.1 channel activator-1		/	Unkown
HY-159090	AT1R antagonist 3		/	Unkown
HY-17402S	Nisoldipine-d6	Inhibitor	/	Unkown
HY-17402S3	Nisoldipine-d3	Inhibitor	/	Unkown
HY-175395	Onychocin B	Inhibitor	/	Unkown
HY-180547	MRC71		/	Unkown
HY-181755	Phenylaminojuglone AJ-2	Inhibitor	/	Unkown
HY-184190	ERG-IN-7	Inhibitor	/	Unkown
HY-184501	UE01		/	Unkown
HY-N12859	Herbacetin 3-O-glucopyranoside-8-O-glucuronopyranoside		/	Unkown
HY-P3269A	Calciseptine TFA	Inhibitor	97.55%	Unkown
HY-W701464	N-Desalkylflurazepam-d4		/	Unkown
HY-Z7760	Felodipine 3,5-dimethyl ester	Modulator	/	Unkown
HY-116307	2-Thio-UTP	Agonist	/	Unkown
HY-122552	Chrysotobibenzyl	Inhibitor	/	Unkown
HY-156889	Cav 3.1 blocker 1	Antagonist	/	Unkown
HY-17402S1	Nisoldipine-d4	Inhibitor	/	Unkown
HY-17402S2	Nisoldipine-d7	Inhibitor	/	Unkown
HY-175226	DPP8/9-IN-2	Inhibitor	/	Unkown
HY-N4189	Isocucurbitacin B		98.98%	Unkown
HY-P3269	Calciseptine	Inhibitor	/	Unkown
HY-RS23990	Cav1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CAV1	MGD	MGI:102709
Felis catus	CAV1	VGNC	VGNC:69367
Rattus norvegicus	CAV1	RGD	RGD:2280
Bos taurus	CAV1	VGNC	VGNC:26799
Canis familiaris	CAV1	VGNC	VGNC:38751
Macaca mulatta	CAV1	VGNC	VGNC:80805
Others	CAV1	NCBI