EBET-1593
EBET-1593 is a BET PROTAC degrader. EBET-1593 can promote the ubiquitination and degradation of BET. EBET-1593 is a lead payload. EBET-1593 can be used to synthesize ADCs, such as 84-EBET. 84-EBET has antitumor effects against pancreatic ductal adenocarcinoma.
(Pink: BET ligand (HY-161387); Blue: E3 ligase ligand; Black: linker).
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- CAS No.: 3031540-97-0
- Formule: C52H57N9O6
- Masse moléculaire:904.07
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
[1]|
BET |
Chemical Information
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CAS No. 3031540-97-0
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Masse moléculaire 904.07
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Formule C52H57N9O6
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SMILES
O=C1NC(CCN1C2=CC(C#CCNC3(CCN(C4CCN(CC4)C5=NC(C(C6=CC=CC=C6)(CO)OC7CC7)=C8C=C(C(C9=C(C%10=O)NC=C9)=CN%10C)C=CC8=N5)CC3)C)=CC=C2OC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EBET-1593 Related Classifications
HY-177244 Related Classifications
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