Anticancer agent 264
Anticancer agent 264 (Compound 5w) is an anticancer agent that exhibits significant antiproliferative activity across tumor cell lines, with an IC50 range of 7.5-33.67 μM. Anticancer agent 264 significantly induces G2/M phase arrest in MDA-MB-231, MIA PaCa-2, and DU-145 cell lines. Anticancer agent 264 reduces the expression of key cell cycle proteins, including CDK1, CDK2, and Cyclin B1, in a dose-dependent manner, and shows strong binding affinity with inhibitor of differentiation (ID) proteins and DNA-binding proteins. Anticancer agent 264 can be used for research in the field of cancer-related diseases.
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- Fòrmula: C23H18ClF5N6O
- Peso molecular:524.87
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Actividad biológica
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Chemical Information
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Actividad biológica
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CDK1/cyclinB1 |
CDK2/cyclinE |
Chemical Information
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Peso molecular 524.87
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Fòrmula C23H18ClF5N6O
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SMILES
ClC1=C(NC(C2=NOC(CN3CCN(C4=C(C(F)=C(C(F)=C4F)F)F)CC3)=N2)=N1)C5=CC=C(C=C5)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 264 Related Classifications
HY-170965 Related Classifications
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