PZ-11
PZ-11 is a derivative of thiazolidinedione with anti-tumor activity. PZ-11 can induce cancer cells apoptosis by downregulating anti-apoptotic gene AIFM1, BAG3 and BIRC3 and regulating pro-apoptotic gene BAD, HRK, CASP10 and CASP10. PZ-11 can be used for research of breast cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C18H11ClN2O5S
- Peso molecular:402.81
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
bad |
Caspase-10 |
caspase 14 |
BIRC3 |
HRK |
In Vitro
PZ-11 shows an IC50 of 17.35 μM against MCF-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 402.81
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Fòrmula C18H11ClN2O5S
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SMILES
ClC1=CC=C(/C=C2SC(N(CC(C3=CC=CC([N+]([O-])=O)=C3)=O)C/2=O)=O)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PZ-11 Related Classifications
HY-180948 Related Classifications
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