2. Gene
  3. SIRT1 - sirtuin 1 Gene

SIRT1 - sirtuin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca fascicularis
Gene ID: 102134009 | Gene type: protein coding

About SIRT1

Primary_assembly 9: 67,382,820-67,418,007 reverse strand.Macaca_fascicularis_6.0:CM021947.1

This gene has 2 transcripts (splice variants), 156 orthologues and 4 paralogues.

SIRT1 Products(3)

mRNA Protein Name
XM_005565730.3 XP_005565787.1 NAD-dependent protein deacetylase sirtuin-1 isoform X1
XM_015456291.2 XP_015311777.1 NAD-dependent protein deacetylase sirtuin-1 isoform X2
XM_045361127.1 XP_045217062.1 NAD-dependent protein deacetylase sirtuin-1 isoform X2

SIRT1 Protein Structure

SIRT1

SIRT1: cd01408 (249 - 484)

  • 0
  • 200
  • 400
  • 600
  • 743 a.a.
Protein Preferred Names Protein Names

NAD-dependent protein deacetylase sirtuin-1

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0150 Nicotinamide Inhibitor 99.99% Unkown
HY-B0879A Suramin sodium salt Inhibitor 99.48% Yes
HY-B0879 Suramin Inhibitor / Unkown
HY-B0150A Nicotinamide Hydrochloride Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-123033A Nicotinamide riboside chloride Activator 99.90% Phase 4
HY-123033 Nicotinamide riboside Activator / Phase 4
HY-123033C Nicotinamide riboside malate Activator / Phase 4
HY-123033B Nicotinamide riboside tartrate Activator / Phase 4
HY-15262 SRT 2104 Activator 99.10% Phase 2
Pre-clinical Phase
Bioactive Molecules (48)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10532 SRT 1720 Activator 99.90% Unkown
HY-107454 OSS_128167 Inhibitor 98.63% Unkown
HY-100578 AGK2 Inhibitor 99.62% Unkown
HY-15145 SRT 1720 monohydrochloride Activator 99.92% Unkown
HY-13515 Sirtinol Inhibitor ≥98.0% Unkown
HY-101278 Thiomyristoyl Inhibitor 99.74% Unkown
HY-100732 Cambinol Inhibitor 99.89% Unkown
HY-124037 SRT 1460 Activator 98.16% Unkown
HY-15869 Inauhzin Inhibitor 99.49% Unkown
HY-N0704 Agrimol B Activator 99.75% Unkown
HY-15510 Tenovin-6 Inhibitor 98.33% Unkown
HY-15145A SRT 1720 dihydrochloride Activator 99.13% Unkown
HY-19759 SRT 2183 Activator 98.17% Unkown
HY-N0341 Scopolin Activator 99.93% Unkown
HY-104073 CAY10602 Activator 98.65% Unkown
HY-101073 Salermide Inhibitor ≥98.0% Unkown
HY-136199 SIRT1-IN-1 Inhibitor 98.19% Unkown
HY-15452A (S)-Selisistat Inhibitor 99.39% Unkown
HY-117006 E1231 Activator 98.55% Unkown
HY-146689 SIRT1-IN-2 Inhibitor 98.86% Unkown
HY-N1926 Dihydrocoumarin Inhibitor 99.81% Unkown
HY-15510B Tenovin-6 Hydrochloride Inhibitor 98.88% Unkown
HY-16616 SIRT-IN-2 Inhibitor 98.08% Unkown
HY-156781 Sirtuin-1 inhibitor 1 Inhibitor 98.09% Unkown
HY-151519 SIRT2-IN-9 Inhibitor 99.45% Unkown
HY-19634 YK-3-237 Activator 99.54% Unkown
HY-122936 Tanshindiol C Activator 98.47% Unkown
HY-16615 SIRT-IN-1 Inhibitor 98.58% Unkown
HY-146690 SIRT1-IN-3 Inhibitor 99.18% Unkown
HY-148408 SIRT2-IN-11 Inhibitor 99.94% Unkown
HY-N3504 Ophiopogonin D' Activator 99.85% Unkown
HY-111329 JGB1741 Inhibitor 99.05% Unkown
HY-19758A Sirtuin modulator 1 Modulator 99.85% Unkown
HY-111303 CHIC35 Inhibitor / Unkown
HY-156027 SIRT6-IN-3 Inhibitor / Unkown
HY-148312 Sirtuin modulator 4 Inhibitor / Unkown
HY-E70008 Lumbokinase capsules Activator / Unkown
HY-N9398 3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol Activator / Unkown
HY-150727 SIRT5 inhibitor 4 Inhibitor / Unkown
HY-155784 SPC-180002 Inhibitor / Unkown
HY-148322 Sirtuin modulator 5 Modulator / Unkown
HY-118343 AC-93253 Inhibitor / Unkown
HY-N10009 Cudraflavone B Activator / Unkown
HY-160617 SIRT2-IN-14 Inhibitor / Unkown
HY-146013 Sirt1/2-IN-1 Inhibitor / Unkown
HY-160944 hsa62 Inhibitor / Unkown
HY-N10125 Ainsliadimer C Activator / Unkown
HY-123241 ZINC08792229 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SIRT1 NCBI NCBI:23411