PZ-11
PZ-11 is a derivative of thiazolidinedione with anti-tumor activity. PZ-11 can induce cancer cells apoptosis by downregulating anti-apoptotic gene AIFM1, BAG3 and BIRC3 and regulating pro-apoptotic gene BAD, HRK, CASP10 and CASP10. PZ-11 can be used for research of breast cancer.
For research use only. We do not sell to patients.
- Formula: C18H11ClN2O5S
- Molecular Weight:402.81
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Caspase Isoforms
More
Biological Activity
|
bad |
Caspase-10 |
caspase 14 |
BIRC3 |
HRK |
PZ-11 shows an IC50 of 17.35 μM against MCF-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 402.81
-
Formula C18H11ClN2O5S
-
SMILES
ClC1=CC=C(/C=C2SC(N(CC(C3=CC=CC([N+]([O-])=O)=C3)=O)C/2=O)=O)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PZ-11 Related Classifications
HY-180948 Related Classifications
Powered by Bioz