Pan-RAS-IN-8
Pan-RAS-IN-8 (Page 152, third row, third from left to right) is a pan-RAS inhibitor. Pan-RAS-IN-8 blocks the binding of RAS to downstream effector molecules by forming a ternary complex, thereby inhibiting the activation of the MAPK and PI3K-AKT signaling pathways. Pan-RAS-IN-8 can be used for the research of cancer, inflammatory diseases and autoimmune diseases.
For research use only. We do not sell to patients.
- Purity : 96.57%
- CAS No.: 3103594-37-9
- Formula: C51H63N9O7S
- Molecular Weight:946.17
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Description
IC50 & Target
[1]|
Ras |
p38 MAPK |
Akt |
PI3K |
Chemical Information
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CAS No. 3103594-37-9
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Appearance Solid
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Molecular Weight 946.17
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Formula C51H63N9O7S
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Color White to off-white
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SMILES
O=C([C@H](CC1=NC2=CS1)NC([C@H]3[C@H](C)[C@@H]3C)=O)N4N[C@H](C(OCC(C)(C)CC5=[C@@]([C@@]6=C([C@H](C)OC)N=CC(C7=NN=C(C8CCN(C9COC9)CC8)O7)=C6)N(CC)C%10=C5C=C2C=C%10)=O)C%11CC4C%11
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)