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Pathways Recommended:	Anti-infection

Results for "

filovirus infection

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Filovirus (3) Dengue Virus (2) EBV (1) Flavivirus (1) Influenza Virus (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Infection (5) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Targets Recommended: Filovirus

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-105070A

Eritoran tetrasodium E5564	EBV Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Eritoran tetrasodium (E5564) is a Toll-like receptor 4 (TLR4) antagonist. Eritoran tetrasodium protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran tetrasodium decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran tetrasodium inhibits pathogenesis of filovirus infection. Eritoran tetrasodium has anti-inflammatory activity .

HY-P99722

Maftivimab REGN3470-3471-3479	Filovirus	Infection
Maftivimab (REGN3470-3471-3479), the inhibitor of *Filovirus, is an Food and agent Administration (FDA)-approved agent. Maftivimab, also named as Atoltivimab, Odesivimab (Inmazeb), can be used for research of Zaire ebolavirus infection* .

HY-U00160

SP187 3 Publications Verification MON-DNJ; UV4	Flavivirus Dengue Virus	Infection
SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.

HY-179691

Antiviral agent 75	Filovirus	Infection
Antiviral agent 75 (example D26) is a Ebolavirus (EBOV) and Bundibugyo ebolavirus (BDBV) inhibitor with IC₅₀s of 0.11 μM and 0.75 μM, respectively. Antiviral agent 75 can be used for the study of filovirus infection .

HY-W143403A

(-)-Isopinocampheol l-Isopinocampheol	Filovirus	Others
(-)-Isopinocampheol (l-Isopinocampheol) is a compound with anti-filovirus activity. Its derivatives inhibit infection by Ebola virus and Marburg virus, possibly through binding to surface glycoproteins. It also has lysosomal affinity.

HY-108023

SP187 hydrochloride MON-DNJ hydrochloride; UV4 hydrochloride	Influenza Virus Dengue Virus	Infection
SP187 hydrochloride (MON-DNJ hydrochloride; UV4 hydrochloride) is an orally active, host-targeting iminosaccharide against filovirus infection. SP187 hydrochloride inhibits endoplasmic reticulum glucosidase. SP187 hydrochloride exhibits antiviral and Dengue Virus activity in vivo. SP187 hydrochloride can be used in antiviral and dengue research .

Cat. No.	상품명	Target	Research Area	Image

HY-P99722

Maftivimab REGN3470-3471-3479	Filovirus	Infection
Maftivimab (REGN3470-3471-3479), the inhibitor of *Filovirus, is an Food and agent Administration (FDA)-approved agent. Maftivimab, also named as Atoltivimab, Odesivimab (Inmazeb), can be used for research of Zaire ebolavirus infection* .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-W143403A

(-)-Isopinocampheol l-Isopinocampheol	Other Monoterpenes Terpenoids Labiatae Plants Source Classification	Filovirus
(-)-Isopinocampheol (l-Isopinocampheol) is a compound with anti-filovirus activity. Its derivatives inhibit infection by Ebola virus and Marburg virus, possibly through binding to surface glycoproteins. It also has lysosomal affinity.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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filovirus infection

Inhibitors & Agonists

Inhibitory Antibodies

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Natural
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