4 Results for "

plasmodial infections

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "plasmodial infections" in MCE Product Catalog:

Sulfalene
Sulfalene
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Cat. No.: HY-A0130
CAS No.: 152-47-6
Synonyms: Sulfametopyrazine; AS-18908
Target:  

Parasite Bacterial

Research Areas:  

Infection Inflammation/Immunology

Sulfalene (Sulfametopyrazine) is an orally active antimalarial agent. Sulfalene competes with para-aminobenzoic acid in plasmodial and bacterial folic acid synthesis pathways. Sulfalene reduces trachoma-associated pathological changes. Sulfalene can be used for the research of acute falciparum malaria, Schistosoma mansoni infection, trachoma, chronic bronchitis, and bacteriuria in pregnancy .
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Sulfalene (Standard)
Sulfalene (Standard)
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Cat. No.: HY-A0130R
CAS No.: 152-47-6
Synonyms: Sulfametopyrazine (Standard); AS-18908 (Standard)
Target:  

Reference Standards Parasite

Research Areas:  

Infection

Sulfalene (Standard) is the analytical standard of Sulfalene. This product is intended for research and analytical applications. Sulfalene (Sulfametopyrazine; AS-18908) is an orally active antimalarial agent. Sulfalene competes for para-aminobenzoic acid binding in plasmodial folic acid synthesis. Sulfalene, combined with Trimethoprim (HY-B0510), clears parasites, resolves fever, and resists induced resistance against drug-sensitive and drug-resistant Plasmodium falciparum. Sulfalene can be used for the research of acute falciparum malaria and Schistosoma mansoni infection .
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Ambigol C
Ambigol C
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Cat. No.: HY-N18878
CAS No.: 850655-31-1
Category:  

Microorganisms Monophenols Phenols

Target:  

Bacterial Endogenous Metabolite Parasite

Ambigol C is an ambigol, Antibacterial agent and Antimalarial agent. Ambigol C is isolated from Fischerella ambigua 108b. Ambigol C exhibits selective antibacterial activity against Gram-positive Staphylococcus aureus strains (including MRSA) with MIC values of 0.98-3.91 μg/mL. Ambigol C also shows potent antibacterial activity against B. megaterium, and possesses weak antimalarial and trypanocidal effects. Ambigol C can be used in the research of bacterial infections, plasmodial infections and trypanosomal infections .
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Cryptolepine
Cryptolepine
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Cat. No.: HY-W800535
CAS No.: 480-26-2
Category:  

Malvaceae Alkaloids Sida acuta Burm. F. Quinoline Alkaloids Plants Indole Alkaloids

Target:  

NF-κB p38 MAPK mTOR Topoisomerase AMPK Apoptosis Cholinesterase (ChE) HIF/HIF Prolyl-Hydroxylase β-catenin

Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties. Cryptolepine acts as an inhibitor of c-Myc, mTOR, NF-κB, HIF-1, MAPK and an activator of AMPKα1/2. It intercalates into DNA, inhibits topoisomerase II (Top II), disrupts mitochondrial dynamics and induces apoptosis. Cryptolepine also exhibits anti-plasmodial and cholinesterase inhibitory activities. Cryptolepine can be used in research related to tumors (melanoma, hepatocellular carcinoma, mammary adenocarcinoma, etc.), malaria, inflammatory diseases and diabetes, particularly in studies focused on inhibiting tumor growth and anti-plasmodial infection .
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