1. Cell Cycle/DNA Damage
  2. CDK
  3. AZD4573

AZD4573 

Cat. No.: HY-112088 Purity: 99.80%
Handling Instructions

AZD4573 is a CDK9 inhibitor with an IC50 of <3 nM extracted from patent US 20160376287 A1, example 14.

For research use only. We do not sell to patients.

AZD4573 Chemical Structure

AZD4573 Chemical Structure

CAS No. : 2057509-72-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 418 In-stock
Estimated Time of Arrival: December 31
5 mg USD 380 In-stock
Estimated Time of Arrival: December 31
10 mg USD 590 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1180 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1850 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2850 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

AZD4573 is a CDK9 inhibitor with an IC50 of <3 nM extracted from patent US 20160376287 A1, example 14.

IC50 & Target

CDK9

3 nM (IC50)

Clinical Trial
Molecular Weight

429.94

Formula

C₂₂H₂₈ClN₅O₂

CAS No.

2057509-72-3

SMILES

ClC1=CN=C(NC([[email protected]]2CCC[[email protected]@H](NC(C)=O)C2)=O)C=C1C3=C(CC(C)(C)C4)N4N=C3

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (290.74 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3259 mL 11.6295 mL 23.2591 mL
5 mM 0.4652 mL 2.3259 mL 4.6518 mL
10 mM 0.2326 mL 1.1630 mL 2.3259 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.81 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.80%

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
AZD4573
Cat. No.:
HY-112088
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