KWZY-11
KWZY-11 (Compound 11) is a potent PARP/CDK6 dual inhibitor with IC50 values of 156.8, 197.3, and 13.3 nM for PARP1, PARP2, and CDK6, respectively. KWZY-11 inhibits tumor cell proliferation by regulating the Wnt/β-catenin signaling pathway. KWZY-11 induces excessive DNA damage and apoptosis in MDA-MB-231 breast cancer cells.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3077131-44-0
- Formel: C28H27ClN8O2
- Molecular Weight:543.02
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
CDK6 13.3 nM (IC50) |
PARP1 156.8 nM (IC50) |
PARP2 197.3 nM (IC50) |
Chemical Information
-
CAS. Nr. 3077131-44-0
-
Molecular Weight 543.02
-
Formel C28H27ClN8O2
-
SMILES
O=C(C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C5=NC6=C(N5)C=CC=C6C(N)=O)Cl)N(C)C
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
KWZY-11 Related Classifications
HY-176713 Related Classifications
Powered by Bioz