DP-C-4
Based on 1 Customer Validation
DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.15%
- CAS No.: 2661609-36-3
- Formule: C72H78ClF2N15O14
- Masse moléculaire:1450.93
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Stockage:
-80°C, stored under nitrogen
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTACs
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Activité biologique
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Cereblon |
DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SW1990 cells
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Concentration:1 μM, 3 μM, 5 μM, 10 μM, 30 μM, 50 μM
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Incubation Time:24 hours
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Result:Had degradation effects on EGFR and PARP simultaneously in SW1990 cells.
Chemical Information
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CAS No. 2661609-36-3
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Appearance Solid
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Masse moléculaire 1450.93
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Formule C72H78ClF2N15O14
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Color Light yellow to green yellow
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SMILES
O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(CCCCCNC(C(NC(CCCCCOC4=C(OC)C=C(N=CN=C5NC6=CC=C(F)C(Cl)=C6)C5=C4)=O)COCC7=CN(CCOCCOCCNC8=CC=CC(C(N9C%10CCC(NC%10=O)=O)=O)=C8C9=O)N=N7)=O)=O)CC3)=O)=C2)C%11=C1C=CC=C%11
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Livraison
Shipping with dry ice.
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Stockage
-80°C, stored under nitrogen
Solvant et solubilité
DMSO : 12 mg/mL (8.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6892 mL | 3.4461 mL | 6.8921 mL | 17.2303 mL |
| 5 mM | 0.1378 mL | 0.6892 mL | 1.3784 mL | 3.4461 mL |
DP-C-4 Related Classifications
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