1. Cell Cycle/DNA Damage
    Epigenetics
    PROTAC
  2. HDAC
    PROTACs
  3. JPS036

JPS036 

Cat. No.: HY-145819
Handling Instructions

JPS036 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS036 degrades class I histone deacetylase (HDAC). JPS036 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells.

For research use only. We do not sell to patients.

JPS036 Chemical Structure

JPS036 Chemical Structure

CAS No. : 2669785-85-5

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Description

JPS036 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS036 degrades class I histone deacetylase (HDAC). JPS036 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1].

Molecular Weight

940.18

Formula

C51H66FN7O7S

CAS No.
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JPS036
Cat. No.:
HY-145819
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