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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
fatty acid beta oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "fatty acid beta oxidation" in MCE Product Catalog:
153
Research Areas:
Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
153
153 Publications Verification
Cat. No.: HY-50202A
CAS No.: 828934-41-4
Synonyms: (R)-(+)-Etomoxir sodium salt
Research Areas:
Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .
22
Category:
Natural Products Neurological Disease Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Nervous System Disorder Disease Research Fields Cancer
Target:
22
22 Cited Publications
Synonyms: (R)-Carnitine hydrochloride; Levocarnitine hydrochloride
Target:
22
22 Cited Publications
Cat. No.: HY-W105518
CAS No.: 36687-82-8
19
Target:
Research Areas:
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
19
19 Cited Publications
Cat. No.: HY-B0968
CAS No.: 13171-25-0
Target:
Research Areas:
Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
3
3 Cited Publications
Cat. No.: HY-N0458
CAS No.: 42719-32-4
Category:
Aquifoliaceae Triterpenes Terpenoids Metabolic Disease Parameria laevigata (Juss.) Moldenke Plants Disease Research Fields
Target:
2
2 Cited Publications
Synonyms: O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride
Category:
2
2 Cited Publications
Synonyms: O-Acetyl-L-carnitine; ALCAR
Category:
2
2 Cited Publications
Synonyms: DL-Carnitine chloride; DL-Levocarnitine chloride
Target:
1
1 Cited Publications
Synonyms: (-)-Lauroylcarnitine
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-B2246S
CAS No.: 2687961-04-0
Synonyms: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride
1
1 Cited Publications
Cat. No.: HY-B0399S
CAS No.: 126827-79-0
Synonyms: (R)-Carnitine-d9; Levocarnitine-d9
Target:
Cat. No.: HY-W015924
CAS No.: 594-61-6
Target:
Cat. No.: HY-E70009
CAS No.: 61116-22-1
Synonyms: ACO
Target:
Research Areas:
Acyl-CoA oxidase (ACO) is a peroxisomal catalyst. Acyl-CoA oxidase acts as a key rate-limiting enzyme in the process of peroxisomal fatty acid β-oxidation. Acyl-CoA oxidase participates in lipid catabolism and phytohormone biosynthesis pathways .
Cat. No.: HY-B2004
CAS No.: 130000-40-7
Research Areas:
Thifluzamide is a fungicide that inhibits fungal respiration by blocking the ubiquinone-binding site in mitochondrial complex II. Thifluzamide exhibits significant activity against Basidiomycota pathogens (such as Rhizoctonia cerealis, Ustilago and Puccinia genera) and is commonly used in studies on wheat sharp eyespot. Thifluzamide displays a dual mechanism in regulating lipid metabolism: it reduces fatty acid synthase activity to inhibit endogenous fatty acid synthesis, and increases carnitine palmitoyltransferase-I activity to accelerate fatty acid β-oxidation, thereby reducing total cholesterol and triglyceride levels in the liver. Thifluzamide also induces hepatotoxicity in zebrafish models and carries a risk of developmental toxicity. Thifluzamide inhibition of Rhizoctonia cerealis may result in low to moderate levels of drug resistance, leading to the generation of stable drug-resistant mutants .
Target:
Category:
Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
