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United States

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Referencia número: HY-170648

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TS-IN-5

TS-IN-5 (Compound 15) is a thymidylate synthase (TS) inhibitor. TS-IN-5 induces Apoptosis by modulating Bax, BCL-2, PI3K, and STAT1 proteins. TS-IN-5 shows antitumor effects against liver, breast and colon cancers.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₁₆H₁₇N₅OS
Peso molecular:327.40

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

TS-IN-5 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas PI3K :

Ver todos los productos específicos de isoformas STAT :

Ver todos los productos específicos de isoformas Bcl-2 Family :

Chemical Information

Peso molecular 327.40
Fòrmula C₁₆H₁₇N₅OS
SMILES

O=C1C(C2=NC3=CC=CC=C3S2)=CNC(N4CCN(C)CC4)=N1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Basiony EA, et al. Rational design, synthesis, biological evaluation, molecular docking, and molecular dynamics of substituted uracil derivatives as potent anti-cancer agents. Bioorg Chem. 2025 Jan;154:108066. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Actividad biológica
- Descripciòn
Chemical Information
Pureza y Documentación
Referencias

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TS-IN-5

Ver todos los productos específicos de isoformas PI3K

Ver todos los productos específicos de isoformas STAT

Ver todos los productos específicos de isoformas Bcl-2 Family

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

TS-IN-5 Related Classifications

HY-170648 Related Classifications