Clemastine

(Synonyms: HS-592; Meclastine)
12 Cited Publications
고객리뷰

Based on 12 publication(s) in Google Scholar

Clemastine (HS-592; Meclastine) is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation.

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  • Purity: 99.26%
  • CAS No.: 15686-51-8
  • 화학식: C21H26ClNO
  • 분자량:343.89
  • 보관:
    Pure form   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Biological Activity
  • Chemical Information
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