470 Results for "

indicators

" in MedChemExpress (MCE) Product Catalog:
Products (470)

470 Results for "indicators" in MCE Product Catalog:

312
MitoSOX Red
MitoSOX Red
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312 Publications Verification
Cat. No.: HY-D1055
CAS No.: 1003197-00-9
MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red.
Excitation/emission wavelength: 510/580 nm.
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188
Dihydroethidium
Dihydroethidium
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188 Cited Publications
Cat. No.: HY-D0079
CAS No.: 104821-25-2
Synonyms: Hydroethidine; PD-MY 003
Dihydroethidium, also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
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63
Fluo-4 AM
Fluo-4 AM
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63 Cited Publications
Cat. No.: HY-101896
CAS No.: 273221-67-3
Fluo-4 AM is a cell-permeable Ca 2+ (calcium ion) indicator (Ex/Em = 485/526 nm) .
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23
Dihydrorhodamine 123
Dihydrorhodamine 123
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23 Cited Publications
Cat. No.: HY-101894
CAS No.: 109244-58-8
Purity:  99.83%
Synonyms: DHR 123
Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
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16
Hypoxanthine
Hypoxanthine
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16 Cited Publications
Cat. No.: HY-N0091
CAS No.: 68-94-0
Synonyms: Purin-6-ol; Sarcine
Category:  

Natural Products Microorganisms Other Diseases Disease markers Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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15
Calcein
Calcein
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15 Cited Publications
Cat. No.: HY-D0040
CAS No.: 1461-15-0
Synonyms: Fluorexon
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
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15
DTNB
DTNB
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15 Cited Publications
Cat. No.: HY-15915
CAS No.: 69-78-3
Synonyms: Ellman’s Reagent
DTNB (Ellman’s Reagent) is a chemical used to quantify the number or concentration of thiol groups .
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13
Hydroxyphenyl Fluorescein
Hydroxyphenyl Fluorescein
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13 Cited Publications
Cat. No.: HY-111330
CAS No.: 359010-69-8
Purity:  99.91%
Synonyms: HPF; 3'-p-(Hydroxyphenyl) fluorescein
Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
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10
BCECF Acetoxymethyl ester
BCECF Acetoxymethyl ester
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10 Cited Publications
Cat. No.: HY-101883A
BCECF Acetoxymethyl ester is a cell membrane permeable compound widely-used as a fluorescent indicator for intracellular pH. BCECF Acetoxymethyl ester could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm .
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10
Fura-2 AM
Fura-2 AM
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10 Cited Publications
Cat. No.: HY-101897
CAS No.: 108964-32-5
Purity:  99%
Synonyms: Fura-2 Acetoxymethyl ester
Fura-2 AM is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
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8
Lucigenin
Lucigenin
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8 Cited Publications
Cat. No.: HY-D0720
CAS No.: 2315-97-1
Synonyms: NSC-151912; L-6868
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .
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8
Resazurin sodium
Resazurin sodium
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8 Cited Publications
Cat. No.: HY-111391
CAS No.: 62758-13-8
Purity:  ≥98.0%
Synonyms: Diazoresorcinol sodium
Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
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7
Mito-FerroGreen
Mito-FerroGreen
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7 Cited Publications
Cat. No.: HY-D2295
Mito-FerroGreen is a mitochondria-specific Fluorescent indicator used to detect mitochondrial Fe 2+ levels (excitation: 488 nm; emission: 500-550 nm). Mito-FerroGreen can be applied to research related to colorectal cancer and chronic heart failure .
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5
Aluminon
Aluminon
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5 Cited Publications
Cat. No.: HY-124493
CAS No.: 569-58-4
Synonyms: ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium
Aluminon (ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) is a complexometric titration indicator and can also be used as a nuclease inhibitor affecting transfection. Aluminon is a kind of biological materials or organic compounds that are widely used in life science research .
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4
Zinpyr-1
Zinpyr-1
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4 Cited Publications
Cat. No.: HY-D0155
CAS No.: 288574-78-7
Zinpyr-1 is a zinc-responsive fluorescent indicator and a membrane-permeable metal-binding probe. Zinpyr-1 forms a complex with Mn 2+ ions and generates a fluorescence turn-on signal. Zinpyr-1 binds to free zinc ions in serum, enabling quantitative detection of free zinc concentration. Zinpyr-1 produces fluorescence signals reflecting the relative zinc concentration in plant root cells, localizes to specific layers of plant root cells, and can be used to support analyses related to plant zinc transporter mutations and homeostasis .
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4
9-Aminoacridine
9-Aminoacridine
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4 Cited Publications
Cat. No.: HY-B1422
CAS No.: 90-45-9
Synonyms: Aminacrine
9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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4
Methylmalonic acid
Methylmalonic acid
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4 Cited Publications
Cat. No.: HY-103395
CAS No.: 516-05-2
Purity:  ≥98.0%
Synonyms: Methylpropanedioic acid; Methylmalonate
Category:  

Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.
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4
Orotic acid potassium
Orotic acid potassium
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4 Cited Publications
Cat. No.: HY-N0157C
CAS No.: 24598-73-0
Synonyms: 6-Carboxyuracil potassium; Vitamin B13 potassium
Orotic acid potassium (Vitamin B13 potassium) is a precursor of pyrimidine bases and is involved in the synthesis of DNA and RNA. Orotic acid potassium stimulates the growth of animals, plants and microorganisms, participates in carbohydrate metabolism, and is necessary for the growth and life activities of organisms. Orotic acid potassium is a measurement indicator in routine newborn screening for urea cycle abnormalities. Orotic acid potassium can cause hepatic steatosis and hepatomegaly in rats .
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4
IR-783
IR-783
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4 Cited Publications
Cat. No.: HY-139109
CAS No.: 115970-66-6
Purity:  99.87%
Synonyms: ADS 780WS
IR-783 (ADS 780WS) is a heptamethine cyanine dye. IR-783 induces Mitochondrial membrane potential loss, ATP depletion, mitochondrial permeability transition pore opening, Cytochrome c release and Apoptosis in breast cancer cells. IR-783 promotes the translocation of Drp1 from the cytosol to mitochondria. IR-783 increases the expression of mitochondrial fission proteins such as MFF and Fission-1. IR-783 possesses imaging, cancer-targeting and anticancer properties. IR-783 exerts anticancer effects against breast cancer. IR-783 can be used in breast cancer-related research .
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4
Brilliant blue G-250
Brilliant blue G-250
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4 Cited Publications
Cat. No.: HY-D0014
CAS No.: 6104-58-1
Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome .
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