2. Apoptosis Cell Cycle/DNA Damage Anti-infection Epigenetics PI3K/Akt/mTOR Autophagy
  3. Apoptosis Topoisomerase Antibiotic AMPK Bacterial Autophagy Mitophagy HIV HBV
  4. Alloc-DOX

Alloc-DOX  (Synonyms: N-Alloc doxorubicin)

製品番号: HY-158329 純度: 98.40%
COA 取扱説明書 Technical Support

Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth.

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Alloc-DOX

Alloc-DOX 構造式

CAS 番号 : 561022-65-9

容量 価格（税別） 在庫状況 数量
5 mg $184 在庫あり
10 mg $299 在庫あり
25 mg $599 在庫あり
50 mg $959 在庫あり
100 mg $1535 お問い合わせ
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Alloc-DOX 関連抗体

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製品説明

Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth[1][2].

分子量

627.59

分子式

C31H33NO13
CAS 番号
Appearance

Solid

Color

Orange to red

SMILES

OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC=C)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (159.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5934 mL 7.9670 mL 15.9340 mL
5 mM 0.3187 mL 1.5934 mL 3.1868 mL
10 mM 0.1593 mL 0.7967 mL 1.5934 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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(per animal)

g

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.40%

COA (253 KB) HNMR (331 KB) LCMS (117 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5934 mL 7.9670 mL 15.9340 mL 39.8349 mL
5 mM 0.3187 mL 1.5934 mL 3.1868 mL 7.9670 mL
10 mM 0.1593 mL 0.7967 mL 1.5934 mL 3.9835 mL
15 mM 0.1062 mL 0.5311 mL 1.0623 mL 2.6557 mL
20 mM 0.0797 mL 0.3983 mL 0.7967 mL 1.9917 mL
25 mM 0.0637 mL 0.3187 mL 0.6374 mL 1.5934 mL
30 mM 0.0531 mL 0.2656 mL 0.5311 mL 1.3278 mL
40 mM 0.0398 mL 0.1992 mL 0.3983 mL 0.9959 mL
50 mM 0.0319 mL 0.1593 mL 0.3187 mL 0.7967 mL
60 mM 0.0266 mL 0.1328 mL 0.2656 mL 0.6639 mL
80 mM 0.0199 mL 0.0996 mL 0.1992 mL 0.4979 mL
100 mM 0.0159 mL 0.0797 mL 0.1593 mL 0.3983 mL
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Alloc-DOX Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alloc-DOX561022-65-9N-Alloc doxorubicinApoptosisTopoisomeraseAntibioticAMPKBacterialAutophagyMitophagyHIVHBVAMP-activated protein kinaseMitochondrial AutophagyHuman immunodeficiency virusHepatitis B virusDoxorubicin prodrugantitumorInhibitorinhibitorinhibit

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