CARM1/HDAC2-IN-1
Based on 1 Customer Validation
CARM1/HDAC2-IN-1 (compound CH-1) is a dual inhibitor against CARM1 and HDAC2, with IC50 values of 3.71 nM and 4.07 nM, respectively. CARM1/HDAC2-IN-1 possesses antitumor activity.
For research use only. We do not sell to patients.
- Purity: 95.17%
- CAS No.: 3074558-69-0
- Formula: C35H42N8O3
- Molecular Weight:622.76
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Histone Methyltransferase Isoforms
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Biological Activity
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CARM1 3.71 nM (IC50) |
HDAC2 4.07 nM (IC50) |
CARM1/HDAC2-IN-1 inhibits proliferation of human prostate cancer cells DU145, RM1, LAPC4, 22RV1 and PC-3, with IC50 values of 0.09 μM , 0.71 μM , 0.68 μM, 0.95 μM and 0.43 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:DU145, RM1, LAPC4, 22RV1 and PC-3
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Concentration:<1 μM
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Incubation Time:72 h
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Result:Reduced proliferations of human prostate cancer cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3074558-69-0
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Appearance Solid
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Molecular Weight 622.76
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Formula C35H42N8O3
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Color White to off-white
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SMILES
CNCCNCC1=CC=CC(C2=NC(NC3=CC(OCCCCCCC(NO)=O)=CC=C3)=C(C(C4=C5C=CNC5=NC=C4)=N2)C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)