CDK4/6/BRD4-IN-1
CDK4/6/BRD4-IN-1 (B15) is an inhibitor of CDK4, CDK6 and BRD4, with IC50 values of 220 nM, 146 nM, 106 nM and 85 nM for BRD4-BD2, BRD4-BD1, CDK6 and CDK4, respectively. CDK4/6/BRD4-IN-1 (B15) can be used in the study of NSCLC (Non-Small Cell Lung Cancer). CDK4/6/BRD4-IN-1 (B15) induces cell cycle arrest and apoptosis.
For research use only. We do not sell to patients.
- Formula: C41H43FN10O6
- Molecular Weight:790.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK4 85 nM (IC50) |
CDK6 106 nM (IC50) |
BD2 220 nM (IC50) |
BD1 146 nM (IC50) |
Chemical Information
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Molecular Weight 790.84
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Formula C41H43FN10O6
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SMILES
O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(C(COC5=C(OC)C=C(C(N6)=NC7=C(C=C(F)C=C7)C6=O)C=C5OC)=O)CC4)C=C3)N=C2N1C8CCCC8)N(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK4/6/BRD4-IN-1 Related Classifications
HY-173237 Related Classifications
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