FAS - Fas cell surface death receptor Gene

Also Known as APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 355

About FAS

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:88,964,050-89,017,059 (from NCBI)

This gene has 61 transcripts (splice variants), 179 orthologues, 21 paralogues and is associated with 71 phenotypes. Ubiquitous expression in colon (RPKM 4.3), lymph node (RPKM 4.0) and 24 other tissues.

Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), Caspase 8, and Caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream Caspase cascade, and leads to Apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the Apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]

FAS Products (5)

mRNA	Protein	Name
NM_000043.6	NP_000034.1	tumor necrosis factor receptor superfamily member 6 isoform 1 precursor
NM_001320619.2	NP_001307548.1	tumor necrosis factor receptor superfamily member 6 isoform 4 precursor
NM_001410956.1	NP_001397885.1	tumor necrosis factor receptor superfamily member 6 isoform 5
NM_152871.4	NP_690610.1	tumor necrosis factor receptor superfamily member 6 isoform 2 precursor
NM_152872.4	NP_690611.1	tumor necrosis factor receptor superfamily member 6 isoform 3 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Références	Source
enables calmodulin binding	IDA IDA: Inferred from direct assay	24914971	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	7536190	GOA
enables kinase binding	IPI IPI: Inferred from physical interaction	7538908	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	7536190	GOA

Biological Process GO Annotation	Evidence	Références	Source
involved in Fas signaling pathway	IMP IMP: Inferred from mutant phenotype	11096076	GOA
acts upstream of or within apoptotic process	IDA IDA: Inferred from direct assay	9681877	GOA
involved in cellular response to amino acid starvation	IMP IMP: Inferred from mutant phenotype	11096076	GOA
involved in cellular response to hyperoxia	IMP IMP: Inferred from mutant phenotype	21382479	GOA
involved in cellular response to mechanical stimulus	IEP IEP: Inferred from expression pattern	19593445	GOA
involved in extrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	22891283	GOA
involved in extrinsic apoptotic signaling pathway via death domain receptors	IDA IDA: Inferred from direct assay	9333124	GOA
involved in necroptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	16507998	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	21625644	GOA
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	20935634	GOA
involved in positive regulation of apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	11096076	GOA
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	11096076	GOA
involved in positive regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	11096076	GOA
involved in regulation of stress-activated MAPK cascade	IMP IMP: Inferred from mutant phenotype	11096076	GOA

Cellular Component GO Annotation	Evidence	Références	Source
part of CD95 death-inducing signaling complex	IDA IDA: Inferred from direct assay	20935634	GOA
located in cell surface	IDA IDA: Inferred from direct assay	22891283	GOA
part of death-inducing signaling complex	IDA IDA: Inferred from direct assay	11101870	GOA
located in membrane raft	IDA IDA: Inferred from direct assay	21382479	GOA
located in plasma membrane	IMP IMP: Inferred from mutant phenotype	21625644	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAS Protein Structure

TNFR_c6

Death

0
100
200
300
335 a.a.

Protein Preferred Names	Protein Names
tumor necrosis factor receptor superfamily member 6	APO-1 cell surface antigen

FAS Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Références
Intra	FAS	P25445	PML	Homo sapiens	P29590	Anti Bait CoIP	21803845
Intra	FAS	P25445	PML	Homo sapiens	P29590	Anti Tag CoIP	21803845
Cross	FAS	P25445	Pdcd6	Mus musculus	P12815	Y2H	11606059
Intra	FAS	P25445	PTPN13	Homo sapiens	Q12923	Anti Bait CoIP	10918185
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Anti Bait CoIP	18328427
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Imaging	16498403
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	CoIP	11717445
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Y2H	7538907
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Anti Bait CoIP	21625644
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Anti Tag CoIP	7538907
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Y2H	7536190
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Anti Bait CoIP	21803845
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Anti Tag CoIP	33961781
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Pull Down	7536190
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	Anti Bait CoIP	17159907
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	CoIP	7536190
Intra	FAS	P25445	FADD	Homo sapiens	Q13158	PLA	25241761
Intra	FAS	P25445	FASLG	Homo sapiens	P48023	PLA	25241761
Intra	FAS	P25445	CAV1	Homo sapiens	Q03135	Anti Bait CoIP	21382479
Intra	FAS	P25445	CAV1	Homo sapiens	Q03135	Confocal	21382479
Intra	FAS	P25445	SRC	Homo sapiens	P12931	Anti Bait CoIP	18328427
Intra	FAS	P25445	DAXX	Homo sapiens	Q9UER7	Pull Down	11003656
Intra	FAS	P25445	DAXX	Homo sapiens	Q9UER7	Anti Bait CoIP	11495919
Intra	FAS	P25445	CASP8	Homo sapiens	Q14790	Anti Bait CoIP	21625644
Intra	FAS	P25445	CASP8	Homo sapiens	Q14790	Anti Tag CoIP	33961781
Intra	FAS	P25445	CASP8	Homo sapiens	Q14790	CoIP	11717445
Intra	FAS	P25445	CASP8	Homo sapiens	Q14790	Anti Bait CoIP	18328427
Intra	FAS	P25445	CASP8	Homo sapiens	Q14790	Imaging	16498403
Intra	FAS	P25445	CASP8	Homo sapiens	Q14790	Anti Bait CoIP	21803845
Intra	FAS	P25445	PML-RAR	Homo sapiens	Q15156	Anti Bait CoIP	21803845
Intra	FAS	P25445	PML-RAR	Homo sapiens	Q15156	Anti Tag CoIP	21803845

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FAS Proteins

Cat. No.	Nom du produit	Accession	Pureté
HY-P7168	Fas/CD95 Protein, Human (HEK293)	P25445 (Q26-S172)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P7169	Fas/CD95 Protein, Human	P25445 (R17-N173)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70329	Fas/CD95 Protein, Human (HEK293, His)	P25445 (Q26-N173)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73047	Fas/CD95 Protein, Human (HEK293, Fc)	P25445 (Q26-N173)	≥ 95%, as determined by reducing SDS-PAGE.

FAS Anticorps

Cat. No.	Nom du produit	Application	Reactivity
HY-P80126	Fas Antibody (YA446)	WB, IHC-P, ICC/IF	Human
HY-P80666	Fas Antibody (YA447)	WB, IHC-F, IHC-P, ICC/IF	Human
HY-P80666A	Fas Antibody (YA447)(PBS only)	WB, IHC-F, IHC-P, ICC/IF	Human
HY-P85515	Fas(C-term) Antibody (YA5207)	WB	Human
HY-P86549	Fas Antibody (YA6241)	WB, IHC-P, ICC/IF, IP, ELISA	Human

Related Diseases

Diseases	Alias
Autoimmune Lymphoproliferative Syndrome	ALPS Canale-Smith Syndrome Autoimmune Lymphoproliferative Syndrome, Type Ia Autoimmune Lymphoproliferative Syndrome, Type Ib Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Css Autoimmune Lymphoproliferative Syndrome, Type 1b Autoimmune Lymphoproliferative Syndrome, Type 1a Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant Fas Deficiency Autoimmune Lymphoproliferative Syndrome 1a ALPS1A Autoimmune Lymphoproliferative Syndrome Type Ia Autoimmune Lymphoproliferative Syndrome 1b ALPS1B Autoimmune Lymphoproliferative Syndrome Type Ib
Lymphoproliferative Syndrome	Lymphoproliferative Disorder Lymphoproliferative Disorders Lymphoproliferative Disorders, Susceptibility To
Vogt-Koyanagi-Harada Disease	Uveomeningoencephalitic Syndrome Uveomenigitic Syndrome Vogt-Koyanagi-Harada Syndrome Harada'S Disease Vogt-Koyanagi Syndrome Vkh Disease Vkh Syndrome Vkh
Splenomegaly
Silicosis	Silicotuberculosis Acute Silicosis Chronic Silicosis Pneumoconiosis Due To Silicates Silica Pneumoconiosis Silicotic Fibrosis Of Lung Accelerated Silicosis Experimental Silicosis
Dianzani Autoimmune Lymphoproliferative Disease	Dald Dianzani Autoimmune Lymphoproliferative Syndrome Autoimmune Lymphoproliferative Syndrome Without Fas Mutations Dianzani Form Of Autoimmune Lymphoproliferative Disease
Lymphopenia	Lymphocytopenia
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Severe Cutaneous Adverse Reaction	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Drug-Induced Stevens Johnson Syndrome Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum Susceptibility To Severe Cutaneous Adverse Reaction Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Lyell'S Syndrome Lyell Syndrome Severe Cutaneous Adverse Reaction, Susceptibility To Hypersensitivity Syndrome, Carbamazepine-Induced, Susceptibility To Hypersensitivity Syndrome, Carbamazepine-Induced Stevens-Johnson Syndrome, Susceptibility To Toxic Epidermal Necrolysis, Susceptibility To Sjs/Ten Susceptibility To Severe Cutaneous Adverse Reaction Ity To Mycoplasma-Induced Stevens Johnson Syndrome Dermatostomatitis, Stevens Johnson Type Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Spectrum Sjs-Ten Toxic Epidermolysis SJS Dermatostomatitis Stevens Johnson Type Ten Sjs/Ten - [Stevens-Johnson Syndrome And Toxic Epidermal Necrolysis] Ten - [Toxic Epidermal Necrolysis]
Hashimoto Thyroiditis	Autoimmune Thyroiditis Hashimoto Struma Hashimoto'S Thyroiditis Chronic Lymphocytic Thyroiditis Lymphocytic Thyroiditis Hashimoto Disease Ht Hashimoto'S Disease Hashimoto'S Syndrome Hypothyroidism, Autoimmune Autoimmune Chronic Lymphocytic Thyroiditis Chronic Lymphocytic Thyroiditides Hashimoto Syndrome Hashimotos Thyroiditis Hashimoto Thyroiditis, Susceptibility To Thyroiditis, Autoimmune Lymphomatous Thyroiditis Lymphoid Thyroiditis Chronic Lymphadenoid Thyroiditis Autoimmune Lymphocytic Chronic Thyroiditis Goitre Lymphomatosa Hashitoxicosis Hashimoto Hypothyroidism Lymphadenoid Goitre Struma Lymphomatosa Hyperthyroidism With Hashimoto Disease Hashimoto Thyrotoxicosis Thyrotoxicosis Due To Hashimoto Thyroiditis Struma Lymphomatosis Lymphadenoid Struma
Viral Hepatitis	Animal Viral Hepatitis Hepatitis, Viral, Animal Human Viral Hepatitis Viral Hepatitis With Hepatic Coma
Caplan'S Syndrome	Caplan Syndrome Caplan'S Disease Caplans Syndrome Rheumatoid Pneumoconiosis
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Liver Disease	Liver Failure Liver Diseases Abnormality Of The Liver Liver Dysfunction Disorder Of Liver Hepatic Disorder Hepatic Disease Disease Of Bilirubin Metabolism Disorder Of Bilirubin Metabolism Liver Decompensation Liver Function Failure Hepatic Failure Nos Liver Failure Nos End Stage Liver Disease Decompensated Liver Failure Decompensation Of Liver Function Hepatic Decompensation Hepatic Insufficiency Liver Cell Necrosis With Hepatic Failure Liver Insufficiency Decompensated Liver Disease End Stage Liver Failure Liver Necrosis With Hepatic Failure
Fatty Liver Disease	Alcoholic Fatty Liver Fatty Liver Fatty Liver, Alcoholic Fatty Change Of Liver Hepatic Lipidosis Steatosis Of Liver Fatty Liver Alcoholic Steatohepatitis Etoh Fatty Liver Etoh Fatty Liver Metamorphosis Fatty Etoh Liver Necrosis
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
Monocytic Leukemia	Monocytic Leukaemia Schilling'S Leukaemia Schilling'S Leukemia M5b Acute Differentiated Monocytic Leukemia
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Sjogren Syndrome	Sicca Syndrome Sjogren'S Syndrome Sjögren Syndrome Sjogren-Gougerot Syndrome Keratoconjunctivitis Sicca Sjögren'S Syndrome Xerodermosteosis Dacryosialoadenopathia Atrophicans Gougerot-Houwer-Sjogren Syndrome Gougerot-Sjogren Syndrome Keratoconjunctivitis Sicca-Xerostomia Secreto-Inhibitor-Xerodermostenosis Primary Sjogren Syndrome Primary Sjogren-Gougerot Syndrome Sjogrens Syndrome Primary Sjogrens Syndrome Dry Eye Syndromes
Autoimmune Hepatitis	Aih Hepatitis, Autoimmune Autoimmune Chronic Active Hepatitis Autoimmune Hepatitis With Centrilobular Necrosis Autoimmune Chronic Hepatitis Hepatitis Autoimmune
Graves' Disease	Graves Disease Exophthalmic Goiter Basedow'S Disease Grave'S Disease Basedow Disease Toxic Diffuse Goiter Graves' Hyperthyroidism Parry Disease Autoimmune Hyperthyroidism Toxic Multinodular Goiter
Aplastic Anemia	Aplastic Anemia, Susceptibility To Anemia Aplastic Idiopathic Aplastic Anemia Secondary Aplastic Anemia Idiopathic Bone Marrow Failure Aplastic Anemia Idiopathic AA Anemia, Aplastic Aplastic Anemia, Idiopathic Erythroid Aplasia Aa - [Aplastic Anaemia] Haematopoietic Aplasia Aleukia Haemorrhagica Anaemia Due To Decreased Red Cell Production Aplasia Bone Marrow Aplastic Bone Marrow Hypoplastic Anaemia Nos Myeloid Bone Marrow Aplasia Pancytopenia Panhaematopenia Hypoproliferative Anaemia Medullary Hypoplasia Red Blood Cells Hypoplastic Anaemia Panmyelophthisis Panhemocytopenia Refractive Hypoproliferative Anaemia Toxic Anaemia Toxic Aplastic Anaemia Aplastic Anaemia Due To Toxic Cause Idiopathic Aplastic Anaemia Nos
Hepatitis	Chronic Hepatitis Chronic Persistent Hepatitis Acute Hepatitis Hepatitis, Chronic Acute And Subacute Liver Necrosis Acute/Subac. Necrosis Of Liver Animal Hepatitis Hepatitis Chronic Hepatitis A Hepatitis, Animal Hepatitis Due To Toxoplasmosis Hepatitis In Toxoplasmosis Toxoplasmal Hepatitis Chronic Hepatitis, Unspecified Chronic Active Hepatitis Nec Other Specified Chronic Hepatitis Chronic Persistent Hepatitis Nec Chronic Lobular Hepatitis Nec
Burkitt Lymphoma	Burkitt'S Lymphoma BL Burkitt Lymphoma, Somatic Burkitt Lymphoma/Leukaemia Burkitt'S Tumor Burkitt'S Tumor Or Lymphoma Malignant Lymphoma, Burkitt'S Type Small Non-Cleaved Cell Lymphoma, Burkitt'S Type Small Non-Cleaved Cell Lymphoma Burkitt Tumor Burkitts Lymphoma Lymphoma, Small Noncleaved-Cell Burkitt Tumour Diffuse Small Noncleaved Malignant Burkitt Lymphoma Malignant Burkitt Lymphoma “Burkitt-Like” Lymphoma Undifferentiated Burkitt Lymphoma Small Noncleaved Cell Burkitt Lymphoma
Syphilis	Chancre Syphilitic Chancre
Pneumoconiosis	Pneumoconioses Silicosis Nos Complicated Silicosis Fibrosis Of Lung With Silicosis Nodular Silicosis Pneumoconiosis Due To Silica Silicotic Fibrosis Of Lung Simple Silicosis Silicatosis Silicotic Lung Fibrosis Pneumoconiosis Due To Talc Pulmonary Talcosis Talc Lung Disease Talc Pneumoconiosis Talc Workers' Pneumoconiosis Talcosis Fibrosis Of Lung Due To Talc Asbestos Pneumoconiosis Amianthosis Asbestosis Lung Fibrosis With Asbestosis Pulmonary Asbestosis
Panniculitis	Nodular Panniculitis
Erythema Multiforme	Dermatostomatitis, Erythema Multiforme Type Em Erythema Multiforme Bullosum Erythema Polymorphe, Erythema Multiforme Type Febrile Mucocutaneous Syndrome Herpes Iris, Erythema Multiforme Type Stevens-Johnson Syndrome Em - [Erythema Multiforme]
Relapsing-Remitting Multiple Sclerosis	Relapsing-Remitting Ms Relapsing Remitting Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Rrms Multiple Sclerosis Relapsing-Remitting
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Lymphoproliferative Syndrome, X-Linked, 1	Lymphomatoid Papulosis Duncan Disease Purtilo Syndrome X-Linked Lymphoproliferative Syndrome Xlp X-Linked Lymphoproliferative Disease XLP1 Lyp Lymphoproliferative Disease, X-Linked Xlpd X-Linked Lymphoproliferative Disease Due To Sh2d1a Deficiency Ebv Infection, Severe, Susceptibility To Ebvs Immunodeficiency 5 Imd5 X-Linked Lymphoproliferative Syndrome 1 Epstein-Barr Virus Infection, Familial Fatal Ebv Infection, Severe Infectious Mononucleosis, Severe Infectious Mononucleosis, Severe, Susceptibility To Immunodeficiency, X-Linked Progressive Combined Variable Epstein Barr Virus Infection, Familial Fatal X-Linked Progressive Combined Variable Immunodeficiency 5 Epstein-Barr Virus-Induced Lymphoproliferative Disease In Males Familial Fatal Epstein-Barr Infection Severe Susceptibility To Ebv Infection Severe Susceptibility To Infectious Mononucleosis Sap Deficiency Sh2d1a/Slam-Associated Protein Deficiency X-Linked Lymphoproliferative Syndrome Type 1 X-Linked Progressive Combined Variable Immunodeficiency Lymphoproliferative Syndrome, X-Linked Sap X-Linked Lymphoproliferative Disorder
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Lymphadenitis	Acute Lymphadenitis Chronic Lymphadenitis Adenitis Chronic Adenitis Acute Adenitis Inflammation Of Lymph Node Adenitis Nos Inflammation Of Gland Lymphatic Gland Inflammation Lymph Gland Inflammation Polyadenitis Chronic Adenitis Of Any Lymph Node Except Mesenteric Chronic Lymphadenitis Except Mesenteric Chronic Non-Specific Lymphadenitis
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Allergic Disease	Hypersensitivity Allergic Hypersensitivity Disease Allergic Condition Allergic Reaction Allergic Disposition
Corneal Dystrophy, Thiel-Behnke Type	Thiel-Behnke Corneal Dystrophy Tbcd CDTB Cdb2 Corneal Dystrophy Of Bowman Layer Type Ii Anterior Limiting Membrane Dystrophy Type Ii Waardenburg-Jonker Corneal Dystrophy Corneal Dystrophy Of Bowman Layer, Type Ii Corneal Dystrophy, Honeycomb-Shaped Corneal Dystrophy Honeycomb-Shaped Corneal Dystrophy Thiel Behnke Type Corneal Dystrophy Honeycomb Shaped Corneal Dystrophy Of The Bowman Layer Type 2 Thiel Behnke Corneal Dystrophy Anterior Limiting Membrane Dystrophy Type 2 Corneal Dystrophy Of Bowman Layer Type 2 Curly Fiber Corneal Dystrophy Honeycomb Corneal Dystrophy Honeycomb-Shaped Corneal Dystrophy Dystrophy, Corneal, Thiel-Behnke Type
Cowpox	Yaba
Human Immunodeficiency Virus Infectious Disease	Hiv Infections
Colon Adenocarcinoma	Adenocarcinoma Of Colon Adenocarcinoma Of The Colon Colonic Adenocarcinoma
Myelodysplastic Syndrome	Myelodysplastic Syndromes Myelodysplasia MDS Myelodysplastic Syndrome Included Myelodysplastic Syndrome, Susceptibility To, Included Myelodysplastic Syndrome, Somatic Myelodysplastic Syndrome, Susceptibility To
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Esophagus Melanoma	Melanoma Of Esophagus Melanoma Of Oesophagus Oesophagus Melanoma Esophageal Melanoma
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma	Cutaneous T-Cell Lymphoma Cutaneous T Cell Lymphoma Lymphoma, T-Cell, Cutaneous Ctcl Lymphoma T-Cell Cutaneous
Digeorge Syndrome	Chromosome 22q11.2 Deletion Syndrome DGS Hypoplasia Of Thymus And Parathyroids Third And Fourth Pharyngeal Pouch Syndrome 22q11.2 Deletion Syndrome Digeorge Sequence Digeorge'S Syndrome Pharyngeal Pouch Syndrome Di-George Syndrome Shprintzen Syndrome
Common Variable Immunodeficiency	Cvid Common Variable Agammaglobulinemia Common Variable Immune Deficiency Acquired Hypogammaglobulinemia Hypogamma-Globulinemia, Acquired Idiopathic Immunoglobulin Deficiency Primary Antibody Deficiency Primary Hypogammaglobulinemia Acquired Agammaglobulinemia Sporadic Hypogammaglobulinemia Common Variable Hypogamma-Globulinemia Immunoglobulin Deficiency, Late-Onset Common Variable Hypogammaglobulinemia Immunodeficiency, Common Variable
Corneal Dystrophy, Reis-Bucklers Type	Reis-Bucklers Corneal Dystrophy Rbcd CDRB Cdb1 Corneal Dystrophy Of Bowman Layer Type I Geographic Corneal Dystrophy Granular Corneal Dystrophy Type Iii Reis-Bucklers' Corneal Dystrophy Anterior Limiting Membrane Dystrophy Type I Corneal Dystrophy Of Bowman Layer Type 1 Corneal Dystrophy Of Bowman Layer, Type I Corneal Dystrophy, Geographic Granular Corneal Dystrophy, Type Iii Corneal Dystrophy Reis Bucklers Type Corneal Dystrophy Geographic Reis Bucklers Corneal Dystrophy Reis Bucklers Dystrophy Anterior Limiting Membrane Dystrophy Type 1 Atypical Granular Corneal Dystrophy Granular Corneal Dystrophy Type 3 Superficial Granular Corneal Dystrophy Corneal Dystrophy Of Bowman Layer, Type 1 Dystrophy, Corneal, Reis-Bucklers Type
Corneal Deposit	Deposits - Cornea
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Guillain-Barre Syndrome	Guillain-Barré Syndrome Acute Inflammatory Polyneuropathy Gbs Acute Inflammatory Demyelinating Polyneuropathy Acute Inflammatory Demyelinating Polyradiculoneuropathy Acute Infective Polyneuritis Acute Inflammatory Demyelinating Polyradiculopathy Acute Postinfectious Polyneuropathy Infectious Neuronitis Post-Infectious Polyneuritis Postinfectious Polyneuritis Acute Autoimmune Peripheral Neuropathy Acute Immune-Mediated Polyneuropathy Acute Inflammatory Neuropathy Guillain-Barré-Strohl Syndrome Landry'S Ascending Paralysis Landry-Guillain-Barre-Strohl Syndrome Post-Infective Polyneuritis Acute Infectious Polyneuritis Fisher Syndrome Landry-Guillain-Barre Syndrome Guillain-Barre-Strohl Syndrome Variant Of Guillain-Barre Syndrome Variant Of Gbs Aidp Acute Idiopathic Demyelinating Polyneuropathy Gbs, Acute Inflammatory Demyelinating Polyradiculoneuropathic Form Guillain-Barre Syndrome, Acute Inflammatory Demyelinating Polyradiculoneuropathic Form Miller Fisher Syndrome
Granular Corneal Dystrophy	Granular Dystrophy Corneal Corneal Dystrophies, Hereditary Hereditary Corneal Dystrophy Corneal Dystrophy Nos Familial Hereditary Corneal Degeneration Hereditary Corneal Opacity
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Shigellosis	Dysentery, Bacillary Bacillary Dysentery Shigella Boydii Infectious Disease Shigella Flexneri Infectious Disease Shigella Gastroenteritis Shigella Sonnei Infectious Disease Shigella Infections
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Hemolytic Anemia	Anemia, Hemolytic Anemia Hemolytic Anaemia Due To Other Disorders Of Glutathione Metabolism Chronic Non Spherocytic Anaemia G6pd - [Glucose-6-Phosphate Dehydrogenase Deficiency] Anaemia Anaemia Due To Glucose-6-Phosphate Dehydrogenase Deficiency Glucose-6-Phosphate Dehydrogenase Deficiency With Anaemia Glucose-6-Phosphate Dehydrogenase Deficiency Anaemia Favism Anaemia Haemolytic Anaemia Due Tog6pd Deficiency Favism Pentose Phosphate Pathway Disorder Anaemia Anaemia Due To Pentose Phosphate Pathway Defect
Intestinal Pseudo-Obstruction	Chronic Intestinal Pseudoobstruction Chronic Intestinal Pseudo-Obstruction Cipo Neuronal Intestinal Dysplasia Hollow Visceral Myopathy Familial Visceral Neuropathy Paralytic Ileus Intestinal Pseudoobstruction Chronic Idiopathic Intestinal Pseudo-Obstruction Ciip Congenital Short Bowel Syndrome Enteric Neuropathy Familial Visceral Myopathy Ipo Pseudo-Obstruction Of Intestine Pseudointestinal Obstruction Syndrome Pseudoobstructive Syndrome Congenital Idiopathic Intestinal Pseudoobstruction Visceral Myopathy, Familial
Hypersensitivity Reaction Type Iv Disease	Immunoproliferative Disorders Immunoproliferative Disease
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
High Grade Glioma	Malignant Glioma Glial Cell Tumor Glioma, Malignant Malignant Neuroglial Tumor Neuroglial Tumor Glioma Malignant Gliomas
Evans' Syndrome	Evans Syndrome Autoimmune Hemolytic Anemia And Autoimmune Thrombocytopenia Evan Syndrome Immune Pancytopenia Evan'S Syndrome
Ectodermal Dysplasia	Congenital Ectodermal Defect Congenital Ectodermal Dysplasia Ectodermal Dysplasia Syndrome Dysplasia, Ectodermal
Type 1 Diabetes Mellitus	Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus Type 1 IDDM Type 1 Diabetes Insulin-Dependent Diabetes Mellitus T1D Juvenile-Onset Diabetes Jod Diabetes Mellitus, Type 1 Diabetes Mellitus, Insulin-Dependent-1 Type I Diabetes Mellitus Autoimmune Diabetes Juvenile Diabetes Juvenile-Onset Diabetes Mellitus Diabetes, Insulin Dependent Insulin-Dependent Diabetes Mellitus-1 Diabetes Mellitus Insulin-Dependent Diabetes Autoimmune Diabetes Mellitus, Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 1, Susceptibility To Diabetes Type 1 Type I Diabetes Diabetes, Autoimmune T1dm - [Type 1 Diabetes Mellitus] Iddm - [Insulin Dependent Diabetes Mellitus] Type 1 Iddm Juvenile Diabetes Mellitus Without Compications Idiopathic Insulin-Dependent Diabetes Mellitus Without Complications Juvenile-Onset Diabetes Mellitus Without Compications Ketosis-Prone Diabetes Mellitus Without Compications Juvenile-Onset-Type Diabetes Mellitus Without Compications
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Viral Infectious Disease	Viral Disease Arbovirus Infections Virus Infection Virus Diseases Viral Infection Viral Infections Virus Infections
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Basal Cell Carcinoma	Basal Cell Cancer Basal Cell Neoplasm Basal Cell Carcinoma Of Skin Malignant Basal Cell Tumor Basal Cell Tumor Epithelioma Basal Cell Malignant Basal Cell Neoplasm Rodent Ulcer Carcinoma Basal Cell Neoplasms, Basal Cell Basal Cell Carcinomas Experimental Organism Basal Cell Carcinoma Nodulo-Ulcerative Basal Cell Carcinoma Basalioma Basal Cell Epithelioma Of Skin Bcc - [Basal Cell Carcinoma] Of Skin Rodent Ulcer Of Skin Rodent Ulcer Of Unspecified Site Basal Cell Epithelioma Of Unspecified Site
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Epithelial-Stromal Tgfbi Dystrophy
Ras-Associated Autoimmune Leukoproliferative Disorder	RALD Autoimmune Lymphoproliferative Syndrome Type 4 Alps4 Autoimmune Lymphoproliferative Syndrome, Type Iv Ras-Associated Autoimmune Leukoproliferative Disease Ras-Associated Autoimmune Lymphoproliferative Syndrome Type Iv, Somatic Alps Type 4 Alps Type Iv Autoimmune Lymphoproliferative Syndrome Type Iv Autoimmune Lymphoproliferative Syndrome 4
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Medulloblastoma	MDB Cpnet Localized Primitive Neuroectodermal Tumor Classic Medulloblastoma Medulloblastoma Predisposition Syndrome Medulloblastoma, Somatic Brain Medulloblastoma Cns Pnet Infratentorial Primitive Neuroectodermal Tumor Neuroectodermal Tumors, Primitive Medulloblastomas Desmoplastic Medulloblastoma Medulloblastoma, With Extensive Nodularity Medulloblastoma Of Unspecified Site Medullomyoblastoma Of Unspecified Site
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Subacute Lymphocytic Thyroiditis
Mixed Oligodendroglioma-Astrocytoma	Who Grade Ii Mixed Glioma
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (2)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-B0515	Ibandronate Sodium Monohydrate	Inducer	99.89%	Unkown
HY-B0515B	Ibandronate Sodium	Inducer	99.89%	Unkown

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Nom du produit	Effect	Pureté	Phase
HY-13721	Phenoxodiol		99.89%	Phase 3

Pre-clinical Phase

Bioactive Molecules (59)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-150190	F5446		99.73%	Unkown
HY-P10102	Kp7-6		99.28%	Unkown
HY-103243	TCPOBOP	Inhibitor	99.70%	Unkown
HY-14414	GSK4112	Inhibitor	99.87%	Unkown
HY-12325	GSK2194069	Inhibitor	99.80%	Unkown
HY-16100	BI 99179	Inhibitor	99.38%	Unkown
HY-N0704	Agrimol B		99.75%	Unkown
HY-112716	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride		99.0%	Unkown
HY-133897	(Rac)-Indoximod		99.60%	Unkown
HY-P10227	Xelafaslatide	Inhibitor	99.88%	Unkown
HY-101849	Fasentin		98.0%	Unkown
HY-N2116	Ginkgolic acid C17:1		99.80%	Unkown
HY-N0686	Pseudoprotodioscin	Inhibitor	99.17%	Unkown
HY-100755	KR-33493	Inhibitor	99.94%	Unkown
HY-21088	3-Amino-2-piperidinone		99.93%	Unkown
HY-N4177	Rubrofusarin gentiobioside	Inhibitor	99.07%	Unkown
HY-Y0598	trans-Chalcone		98.79%	Unkown
HY-129624A	Bisindolylmaleimide VIII acetate		99.68%	Unkown
HY-P6440	Met-12	Inhibitor	99.66%	Unkown
HY-122394	Thiolactomycin	Inhibitor	≥97.0%	Unkown
HY-160912	ELOVL6-IN-5	Inhibitor	95.47%	Unkown
HY-N6777	Penicillic acid	Inhibitor	99.83%	Unkown
HY-103347	M50054	Inhibitor	98.44%	Unkown
HY-113963	Ac-IETD-CHO	Inhibitor	98.59%	Unkown
HY-103348	Boc-Asp(OMe)-fluoromethyl ketone	Inhibitor	98.0%	Unkown
HY-N3011	Iridin		99.72%	Unkown
HY-N7930	Crenulatin		99.85%	Unkown
HY-N12717	Casuarinin		98.24%	Unkown
HY-N0853A	Alisol A 24-acetate		98.0%	Unkown
HY-108610C	(S)-Edelfosine	Inducer	99.90%	Unkown
HY-N12378	β-Patchoulene		96.88%	Unkown
HY-P10815	IP3RCYT	Inhibitor	95.87%	Unkown
HY-RS04753	FASN Human Pre-designed siRNA Set A		/	Unkown
HY-RS04754	Fasn Mouse Pre-designed siRNA Set A		/	Unkown
HY-N7521	Procyanidin C2		/	Unkown
HY-111165	SNX-7081		/	Unkown
HY-103323	Fas C-Terminal Tripeptide	Inhibitor	/	Unkown
HY-118147	ML356	Inhibitor	/	Unkown
HY-146197	Apoptotic agent-1	Inducer	/	Unkown
HY-167879	(Rac)-NPD6433	Inhibitor	/	Unkown
HY-168877	FMP	Activator	/	Unkown
HY-174133	HSD17B13-IN-104	Inhibitor	95.0%	Unkown
HY-175057	Ac-IETD-CHO TFA	Inhibitor	/	Unkown
HY-184685	Antimycobacterial agent-18	Inhibitor	/	Unkown
HY-N6777S	Penicillic acid-13C8		/	Unkown
HY-P3779	Amyloid 17-42	Inducer	/	Unkown
HY-P5797	Fasciculin-II	Inhibitor	/	Unkown
HY-P5798	Fasciculin-I	Inhibitor	/	Unkown
HY-RS04751	FAS Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-129624	Bisindolylmaleimide VIII		/	Unkown
HY-167879A	NPD6433	Inhibitor	/	Unkown
HY-168770	Cl-Necrostatin-1	Inhibitor	/	Unkown
HY-174713	Human FASLG mRNA		/	Unkown
HY-174714	Human FAS mRNA		/	Unkown
HY-N10612	Petasin		/	Unkown
HY-N5134A	ara-GMP		/	Unkown
HY-P10401	TAT-GluR6-9c	Antagonist	/	Unkown
HY-RS16712	Fas Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23147	Fas Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (3)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-P99133	Anti-Mouse Fas Ligand Antibody (MFL3)	Inhibitor	/	Unkown
HY-P991606	TRX585		/	Unkown
HY-P992072	Anti-Human/Mouse CD95 Antibody (HFE7A)		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FAS	VGNC	VGNC:28869
Mus musculus	FAS	MGD	MGI:95484
Canis familiaris	FAS	VGNC	VGNC:40734
Rattus norvegicus	FAS	RGD	RGD:619831
Macaca mulatta	FAS	VGNC	VGNC:72479
Others	FAS	NCBI