2. Apoptosis
  3. Apoptosis Bcl-2 Family
  4. Flurochloridone

Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. Flurochloridone induces endoplasmic reticulum (ER) stress and activated unfolded protein response (UPR) signaling pathways. Flurochloridone impairs cell viability and induces cytotoxicity and apoptosis mediated by ER stress via activating eIF2α-ATF4/ATF6-CHOP-Bim/Bax signaling pathways in TM4 cells.

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Flurochloridone Chemical Structure

Flurochloridone Chemical Structure

CAS No. : 61213-25-0

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Flurochloridone Related Antibodies

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Description

Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. Flurochloridone induces endoplasmic reticulum (ER) stress and activated unfolded protein response (UPR) signaling pathways. Flurochloridone impairs cell viability and induces cytotoxicity and apoptosis mediated by ER stress via activating eIF2α-ATF4/ATF6-CHOP-Bim/Bax signaling pathways in TM4 cells[1][2].

Molecular Weight

312.12

Formula

C12H10Cl2F3NO
CAS No.
SMILES

O=C1N(CC(C1Cl)CCl)C2=CC=CC(C(F)(F)F)=C2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Flurochloridone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flurochloridone61213-25-0R-40244R40244R 40244ApoptosisBcl-2 FamilyherbicideapoptosisInhibitorinhibitorinhibit

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