CDK8-IN-19
CDK8-IN-19 (Compound 3d) is a CDK8 inhibitor with an IC50 of 25.08 nM. CDK8-IN-19 has a broad-spectrum anticancer activity, such as leukemia, melanoma and breast cancer, without significant cytotoxic effect on the normal Vero cells (mean IC50s of 2.87, 3.65, 3.79 and 45.48 μM, respectively).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C17H11Cl2N3OS2
- 분자량:408.32
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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CDK8/cyclin C 25.08 nM (IC50) |
PI3Kα 86.62 nM (IC50) |
CDK2/CycA2 1.13 μM (IC50) |
Chemical Information
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분자량 408.32
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화학식 C17H11Cl2N3OS2
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SMILES
S=C(NC1=CC=C(Cl)C=C1Cl)NC(S/C2=C/C3=CC=CC=C3)=NC2=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK8-IN-19 Related Classifications
HY-176282 Related Classifications
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