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Cat. No.: HY-168664

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CPD-39

고객리뷰

Based on 1 Customer Validation

CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation.
(Pink: CDK4 and CCND1 ligand (HY-50767); Blue: VHL ligand (HY-168667); Black: linker (HY-20240)).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 98.06%
CAS No.: 3055472-38-0
화학식: C₄₆H₅₇N₁₅O₄
분자량:884.04

보관:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

CPD-39 Chemical Structure

CAS No.: 3055472-38-0

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
용액&용해도
- In Vitro
순도&문서
References
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation^[1]. (Pink: CDK4 and CCND1 ligand (HY-50767); Blue: VHL ligand (HY-168667); Black: linker (HY-20240)).

IC₅₀ & Target^[1].

CDK4

CCND1

All PROTACs Isoforms :

All CDK Isoforms :

Chemical Information

CAS No. 3055472-38-0
Appearance Solid
분자량 884.04
화학식 C₄₆H₅₇N₁₅O₄
Color Light yellow to yellow
SMILES

CC(C1=C(C2=C(N(C1=O)C3CCCC3)N=C(N=C2)NC4=CC=C(C=N4)N5CCN(CC5)CC(NC6CC7(CC(C7)NC8=NC(NC)=CC=C8C(NC9=NN=C(C=C9)N(C)C)=O)C6)=O)C)=O
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 100 mg/mL (113.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.1312 mL

5.6559 mL

11.3117 mL

5 mM

0.2262 mL

1.1312 mL

2.2623 mL

10 mM

0.1131 mL

0.5656 mL

1.1312 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jing Liu, et al. Compounds and methods of treating cancers. French, WO2024183798A1.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.1312 mL	5.6559 mL	11.3117 mL	28.2793 mL
	5 mM	0.2262 mL	1.1312 mL	2.2623 mL	5.6559 mL
	10 mM	0.1131 mL	0.5656 mL	1.1312 mL	2.8279 mL
	15 mM	0.0754 mL	0.3771 mL	0.7541 mL	1.8853 mL
	20 mM	0.0566 mL	0.2828 mL	0.5656 mL	1.4140 mL
	25 mM	0.0452 mL	0.2262 mL	0.4525 mL	1.1312 mL
	30 mM	0.0377 mL	0.1885 mL	0.3771 mL	0.9426 mL
	40 mM	0.0283 mL	0.1414 mL	0.2828 mL	0.7070 mL
	50 mM	0.0226 mL	0.1131 mL	0.2262 mL	0.5656 mL
	60 mM	0.0189 mL	0.0943 mL	0.1885 mL	0.4713 mL
	80 mM	0.0141 mL	0.0707 mL	0.1414 mL	0.3535 mL
	100 mM	0.0113 mL	0.0566 mL	0.1131 mL	0.2828 mL

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
용액&용해도
- In Vitro
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

CPD-39

Cell Cycle/DNA Damage Compound Library

Anti-Cancer Compound Library

Anti-Aging Compound Library

Orally Active Compound Library

Anti-Pancreatic Cancer Compound Library

Anti-Blood Cancer Compound Library

Anti-Hematopathy Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Protein Kinase Compound Library

Cell Proliferation Compound Library

High-Throughput Bioactive Compound Library

All PROTACs Isoforms

All CDK Isoforms

Biological Activity

Chemical Information

용액&용해도

순도&문서

References

Help & FAQs

Complete Stock Solution Preparation Table

CPD-39

Cell Cycle/DNA Damage Compound Library

Anti-Cancer Compound Library

Anti-Aging Compound Library

Orally Active Compound Library

Anti-Pancreatic Cancer Compound Library

Anti-Blood Cancer Compound Library

Anti-Hematopathy Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Protein Kinase Compound Library

Cell Proliferation Compound Library

High-Throughput Bioactive Compound Library

All PROTACs Isoforms

All CDK Isoforms

Biological Activity

Chemical Information

용액&용해도

순도&문서

References

Help & FAQs

Complete Stock Solution Preparation Table

CPD-39 Related Classifications

HY-168664 Related Classifications