Multi-target kinase-IN-7
Multi-target kinase-IN-7 (Compound 1e) is an orally active multi-target kinase inhibitor (IC50 values: CDK2=0.314 μM, EGFR=0.183 μM, HER-2=0.197 μM, VEGFR-2=0.235 μM). Multi-target kinase-IN-7 is promising for research of solid tumors (e.g., lung, breast, prostate cancer).
For research use only. We do not sell to patients.
- CAS No.: 301820-47-3
- Formula: C20H14N2O2S
- Molecular Weight:346.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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CDK2 0.314 μM (IC50) |
HER2 0.197 μM (IC50) |
VEGFR2 0.235 μM (IC50) |
Chemical Information
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CAS No. 301820-47-3
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Molecular Weight 346.40
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Formula C20H14N2O2S
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SMILES
O=C(/C(N1)=C/C2=CC=C3C=CC=CC3=C2O)N(C4=CC=CC=C4)C1=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Multi-target kinase-IN-7 Related Classifications
HY-178157 Related Classifications
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