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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
fluorescent fatty acid
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "fluorescent fatty acid" in MCE Product Catalog:
7
7 Publications Verification
7
7 Publications Verification
Cat. No.: HY-W127715
CAS No.: 71206-95-6
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3
3 Cited Publications
Cat. No.: HY-108910A
CAS No.: 9004-07-3
Synonyms: EC 3.4.21.1 (MS grade); Chymotrypsin A (MS grade)
Target:
Research Areas:
Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) (MS grade) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin (MS grade) downregulates the TLR4/NF-κB signaling pathway, inhibits the release of inflammatory factors, reduces cell infiltration and tissue damage, and also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54). It can also be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin (MS grade) has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions, and can be used in the research of diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin (MS grade) can be used in studies of inflammation, edema, and expectoration .
2
2 Cited Publications
Cat. No.: HY-D1617
CAS No.: 144672-74-2
Cat. No.: HY-D1736
CAS No.: 158757-82-5
Cat. No.: HY-N16308
CAS No.: 3091879-77-2
Category:
Target:
Cat. No.: HY-W020012
CAS No.: 78949-95-8
Synonyms: 22-NBD Cholesterol
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Research Areas:
Fluoresterol (22-NBD Cholesterol) is a cholesterol-specific fluorescent probe with cholesterol-mimicking binding properties. Fluoresterol is ineffective orally and does not cross the blood-brain barrier. Fluoresterol specifically binds to cholesterol transport-related proteins (such as ABCA1 and ABCG1) and is primarily used in cholesterol metabolism research, particularly for the visualization and quantitative analysis of cholesterol absorption, efflux, intracellular transport efficiency, and reverse cholesterol transport (RCT) processes. The commonly used concentration of Fluoresterol in in vitro experiments is 0.1-10 μM, and the commonly used dose in in vivo experiments is 5-20 mg/kg (gavage or intraperitoneal injection), with excitation/emission wavelengths of 472/540 nm. Fluoresterol can be applied to the study of cholesterol metabolism mechanisms related to hyperlipidemia, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD) .
Cat. No.: HY-D1610
CAS No.: 217075-24-6
Cat. No.: HY-168375
CAS No.: 1246809-50-6
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BODIPY-Palmitate is a fluorescently labeled palmitic acid (HY-N0830), with excitation/emission maxima at 488/508 nm. BODIPY-Palmitate can be used to detect fatty acid uptake and metabolism .
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DAUDA is a fluorescent fatty acid analog probe, with Kd values of 0.63 μM, 0.82 μM, and 0.66 μM against subtypes/mutants of Schistosoma mansoni Sm14 fatty acid-binding protein, respectively. DAUDA binds to Sm14 fatty acid-binding protein variants, enters their non-polar binding pockets and alters fluorescence emission properties. DAUDA serves as a tracer in competitive binding assays with natural fatty acids to evaluate the fatty acid-binding capacity of Sm14 protein variants. DAUDA is applicable to the research of schistosomiasis .
Cat. No.: HY-120957
CAS No.: 862913-13-1
Synonyms: AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide
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Research Areas:
AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.
Cat. No.: HY-D0036
CAS No.: 35231-44-8
Synonyms: 4-Bromomethyl-7-methoxycoumarin
Synonyms: dhCerC6NBD
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9-Aminophenanthrene is a type of polycyclic aromatic amine compound, which can be used as a fluorescent labeling reagent for free fatty acids (FFA) .
Cat. No.: HY-N15885
CAS No.: 117056-67-4
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Target:
Cat. No.: HY-185287
CAS No.: 2101952-37-6
Research Areas:
TUG-1609 is a fluorescent tracer targeting free fatty acid receptor 2 (FFA2/GPR43) with a Kd value of 65.1 nM .
Cat. No.: HY-D3398
Target:
Research Areas:
FlavAc is a fluorescent dye (with an excitation wavelength of 980 nm) for real-time in vivo imaging of lipid metabolism disorders, including early fatty liver disease and atherosclerotic plaques. FlavAc specifically integrates into endogenous lipoproteins, primarily low-density lipoprotein (LDL), and shows no brightness enhancement when bound to albumin. FlavAc forms aggregates in aqueous solutions, leading to fluorescence quenching; however, when integrated into lipoproteins, such aggregation decreases, forming stable fluorescent complexes with enhanced brightness. FlavAc can selectively illuminate LDL upon laser irradiation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
