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Cat. No.: HY-N16409

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Berkeleyamide C

Berkeleyamide C is a selective matrix metalloproteinase-3 (MMP-3) and caspase-1 inhibitor. Berkeleyamide C blocks MMP-3-mediated tumor cell invasion and metastasis, as well as the abnormal activation of inflammation and apoptosis related to caspase-1. Berkeleyamide C is promising for research of cancers and inflammation-related diseases.

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CAS No.: 1019854-23-9
화학식: C₂₂H₂₆N₂O₆
분자량:414.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Berkeleyamide C Chemical Structure

CAS No.: 1019854-23-9

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

MMP-3

Caspase-1

All MMP Isoforms :

All Caspase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]
HeLa	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]
HL-60	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]
K562	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]

Chemical Information

CAS No. 1019854-23-9
분자량 414.45
화학식 C₂₂H₂₆N₂O₆
SMILES

CC(O[C@@H](C1=CC=CC=C1)C(N(C=C2C(NC(CC(C)C)=O)=O)CCO)=CC2=O)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Penicillium rubrum
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stierle AA, et al. The berkeleyamides, amides from the acid lake fungus Penicillum rubrum. J Nat Prod. 2008 May;71(5):856-60. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

견적 받기 해외재고보유

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

Berkeleyamide C

All MMP Isoforms

All Caspase Isoforms