Cibinetide acetate
Based on 6 publication(s) in Google Scholar
Cibinetide (ARA290) acetate is an erythropoietin (EPO) derivative that acts as a specific agonist of the erythropoietin/CD131 heteroreceptor. ICibinetide acetate can be used in the research of neurological disorders.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C51H84N16O21.xC2H4O2
- Molecular Weight:1257.31 (free base)
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Cibinetide acetate
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IHC
Biologische Aktivität
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 1257.31 (free base)
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Formel C51H84N16O21.xC2H4O2
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SMILES
OC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCC(N1)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)CO)=O)CO)=O.CC(O)=O.[x]
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Synonyms
ARA290 acetate
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Sequence
{Glp}-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
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Sequence Shortening
{Glp}-EQLERALNSS
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (6)
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Journal Impact Factor
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Most Recent
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CNS Neurosci Ther
Erythropoietin-derived peptide ARA290 mediates brain tissue protection through the β-common receptor in mice with cerebral ischemic stroke. [Abstract]2024 Mar;30(3):e14676. PMID: 38488446 -
Immunology
EPOR activation attenuates colitis via enhancing LC3B-dependent apoptotic cell clearance. [Abstract]2025 Sep;176(1):33-48. PMID: 37204242 -
Int J Mol Sci
2024 Mar 29;25(7):3854. PMID: 38612664 -
Toxicol In Vitro
An engineered non-erythropoietic erythropoietin-derived peptide, ARA290, attenuates doxorubicin induced genotoxicity and oxidative stress. [Abstract]2020 Aug;66:104864. PMID: 32335150
Cibinetide acetate purchased from MedChemExpress. Usage Cited in: Toxicol In Vitro. 2020 Aug;66:104864. [Abstract]
Representative photomicrographs demonstrate the results of the TUNEL assay. Alterations in apoptotic cells are assessed using the ratio of green fluorescence. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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Reinheit & Dokumentation
Verweise
[1]. Hache G, et al. ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability. Shock. 2016 Oct;46(4):390-7. [Content Brief]
[2]. Carole Muller, et al. ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats. Mol Med. 2015; 21(1): 969–978. [Content Brief]
[3]. Chen H, et al. Therapeutic effects of nonerythropoietic erythropoietin analog ARA290 in experimental autoimmune encephalomyelitis rat. J Neuroimmunol. 2014 Mar 15;268(1-2):64-70. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Cibinetide acetate Related Classifications
HY-P0168A Related Classifications
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