BDE30671203
BDE30671203 is a highly selective PLK1 inhibitor (IC50 = 2.163 nM). BDE30671203 induces G2/M phase arrest and Apoptosis. BDE30671203 downregulates key cell cycle regulators (CDC20, CDK1) and the anti-apoptotic gene Bcl-2. BDE30671203 exhibits anticancer activity against non-small cell lung cancer, large cell lung cancer, and liver cancer.
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- Fòrmula: C26H34N8O
- Peso molecular:474.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
PLK1 2.163 nM (IC50) |
PLK2 >10000 nM (IC50) |
PLK3 >10000 nM (IC50) |
CDK1 |
Bcl-2 |
Chemical Information
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Peso molecular 474.60
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Fòrmula C26H34N8O
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SMILES
O=C(N1CC(CC2=NC(N3CCN(C)CC3)=CC(NC4=CC(C)=NN4)=N2)CCC1)C5=CC=CC=C5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BDE30671203 Related Classifications
HY-181030 Related Classifications
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