Ebp - phenylalkylamine Ca2+ antagonist (emopamil) binding protein Gene

Also Known as SI; Td; mSI; Pabp

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13595

Summary

This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum. This protein catalyses the conversion of delta8 to delta7 sterols, an important step in sterol biosynthesis. Mutations in this gene are responsible for the mouse tattered mutant phenotype. Tattered males are embryonic lethal, while heterozygous females have developmental defects. Deficiency of the related gene in human causes X-linked dominant chondrodysplasia punctata. [provided by RefSeq, May 2015]

Ebp Products (2)

mRNA Protein Name
NM_007898.3 NP_031924.1 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
NM_007898.3 NP_031924.1 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Protein Preferred Names Protein Names

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

  • D8-D7 sterol isomerase

  • cholestenol Delta-isomerase

  • delta(8)-Delta(7) sterol isomerase

  • tattered

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0660 Eicosapentaenoic Acid Activator 98.09% Yes
HY-10466 Daclatasvir Inhibitor 99.57% Unkown
HY-10465 Daclatasvir dihydrochloride Inhibitor 99.82% Unkown
HY-10237 Boceprevir Inhibitor 98.52% Unkown
HY-W011269 Eicosapentaenoic Acid sodium Activator 95.78% Yes

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-132607A MTL-CEBPA sodium 91.62% Phase 2
HY-132607 MTL-CEBPA 95.52% Phase 2
HY-13766 Timcodar Inhibitor 99.66% Phase 2
HY-132168 RMC-5552 Inhibitor 99.94% Phase 1

Pre-clinical Phase

Bioactive Molecules (82)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-110188 BiP inducer X Inhibitor 99.62% Unkown
HY-N4103 Fucosterol Inhibitor 98.27% Unkown
HY-12461 WS6 99.30% Unkown
HY-164561 TASIN-30 99.96% Unkown
HY-116572A TASIN-1 98.09% Unkown
HY-N0704 Agrimol B 99.75% Unkown
HY-162351 EBP-IN-1 Inhibitor 99.77% Unkown
HY-N1677 2,6-Dimethoxy-1,4-benzoquinone 98.72% Unkown
HY-N6954 Garcinone C 99.51% Unkown
HY-N0777 Isorhamnetin-3-O-glucoside 99.96% Unkown
HY-12462 WS3 98.70% Unkown
HY-N0656A (+)-Usnic acid 99.64% Unkown
HY-N4177 Rubrofusarin gentiobioside Inhibitor 99.07% Unkown
HY-114519 Helenalin acetate Inhibitor 99.55% Unkown
HY-134334 C/EBPα inducer 1 99.82% Unkown
HY-115590 JP-11646 98.74% Unkown
HY-N14035 Garcinia cambogia extract Activator / Unkown
HY-134333 ICCB280 Activator 98.14% Unkown
HY-143510 RMC-4627 99.20% Unkown
HY-128671 6-​Thioinosine 99.31% Unkown
HY-P5275 Tripeptide-41 99.30% Unkown
HY-W348485 WRX606 Inhibitor 95.65% Unkown
HY-130723A AMPK activator 2 hydrochloride Activator 99.68% Unkown
HY-134903 (32-Carbonyl)-RMC-5552 Inhibitor 95.41% Unkown
HY-N11709 Theasaponin E1 99.08% Unkown
HY-P10323A T7 Peptide TFA 98.20% Unkown
HY-114267 Cbz-B3A Inhibitor 98.63% Unkown
HY-176761 NSC647889 99.28% Unkown
HY-N15574 Saringosterol ≥90.0% Unkown
HY-RS04277 EIF4EBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W412264 Pim-1/2 kinase inhibitor 1 Inhibitor 99.78% Unkown
HY-124348 DM-PIT-1 Inhibitor 99.9% Unkown
HY-172609 SL-176 99.91% Unkown
HY-N3027 Soyasaponin Aa Inhibitor 99.88% Unkown
HY-N4253 Kudinoside D 99.80% Unkown
HY-N7661 4β-Hydroxywithanolide E Inhibitor 98% Unkown
HY-P11642A Sialorphin TFA / Unkown
HY-111370 mTOR inhibitor-2 Inhibitor / Unkown
HY-10237S Boceprevir-d9 Inhibitor / Unkown
HY-10062 AZD3409 Inhibitor / Unkown
HY-10466BS Daclatasvir-d6 hydrochloride / Unkown
HY-10466S Daclatasvir-d6 Inhibitor 99.64% Unkown
HY-10466S2 Daclatasvir-d16 Inhibitor / Unkown
HY-115869 RMC-4529 Inhibitor / Unkown
HY-119831 Rohitukine / Unkown
HY-121033 BS148 / Unkown
HY-122670 VS-II-173 / Unkown
HY-126956 Porphyra 334 / Unkown
HY-130723 AMPK activator 2 Activator / Unkown
HY-149292 SR-4133 Inhibitor / Unkown
HY-157482 EBP-59 Inhibitor / Unkown
HY-157828 DSP-0390 Inhibitor / Unkown
HY-169751 Dihydro-N-caffeoyltyramine Inhibitor / Unkown
HY-176948 M-1111 Inhibitor / Unkown
HY-181650 T133 / Unkown
HY-181925 FD2024 / Unkown
HY-182957 MNK/PIM-IN-2 / Unkown
HY-B0660S1 Eicosapentaenoic acid 1,2,3,4,5-13C5 Activator / Unkown
HY-B0660S2 Eicosapentaenoic acid-d10 / Unkown
HY-N11507 Tibesaikosaponin V Inhibitor / Unkown
HY-N15121 4-O-Methyl-ascochlorin / Unkown
HY-N3027R Soyasaponin Aa (Standard) Inhibitor / Unkown
HY-N4103R Fucosterol (Standard) Inhibitor / Unkown
HY-P10323 T7 Peptide / Unkown
HY-P11642 Sialorphin / Unkown
HY-P6183 LXJ-02 Inducer / Unkown
HY-RS04130 EBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04278 EIF4EBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04279 EIF4EBP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05464 GLB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12834 SH3D19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-10466S1 Daclatasvir-13C2,d6 Inhibitor / Unkown
HY-116572 TASIN-1 hydrochloride / Unkown
HY-B0660A Eicosapentaenoic acid metformin Activator / Unkown
HY-N10612 Petasin / Unkown
HY-N1677R 2,6-Dimethoxy-1,4-benzoquinone (Standard) / Unkown
HY-RS18892 Ebp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20227 Eif4ebp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20664 Eif4ebp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25383 Ebp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26734 Eif4ebp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27175 Eif4ebp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ebp NCBI NCBI:10682