Gal - galanin and GMAP prepropeptide Gene

Also Known as Galn

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29141

Summary

Predicted to enable Galanin receptor activity; Galanin receptor binding activity; and neuropeptide hormone activity. Involved in several processes, including regulation of glucocorticoid metabolic process; response to estrogen; and response to Insulin. Located in Golgi apparatus and secretory granule. Biomarker of brain ischemia; hypertension; mononeuropathy; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in familial temporal lobe epilepsy 8. Orthologous to human GAL (Galanin and GMAP prepropeptide). [provided by Alliance of Genome Resources, Apr 2022]

Gal Products (1)

mRNA Protein Name
NM_033237.1 NP_150240.1 galanin peptides preproprotein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in feeding behavior IDA
IDA: Inferred from direct assay
9794487 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12119556 RGD
involved in negative regulation of lymphocyte proliferation IDA
IDA: Inferred from direct assay
12119556 RGD
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
12119556 RGD
involved in regulation of glucocorticoid metabolic process IMP
IMP: Inferred from mutant phenotype
17273801 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
1711463 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
10350643 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
8738309 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15526991 RGD
Cellular Component GO Annotation Evidence Références Source
located in secretory granule IDA
IDA: Inferred from direct assay
1711463 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

galanin peptides

  • galanin prepropeptide

  • galanin/GMAP prepropeptide

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Nom du produit Effect
Pureté Rare Diseases
HY-14929A Migalastat hydrochloride Inhibitor 99.70% Yes
HY-14929 Migalastat Inhibitor / Unkown

Clinical Phase

Bioactive Molecules (9)
Cat. No. Nom du produit Effect
Pureté Phase
HY-114440 Belapectin 98.94% Phase 3
HY-W013053 Dibenz[a,h]anthracene Inducer 98.0% Phase 3
HY-100717 HT-2157 Antagonist 98.0% Phase 2
HY-E70052 alpha-1,3-Galactosyltransferase (a1,3GalT) / Phase 2
HY-136527 BMS-986251 / Phase 2
HY-156996 AGI-134 / Phase 2
HY-100443 PX20606 Agonist / Phase 1
HY-139562 BMS-986318 Agonist / Phase 1
HY-158460 Alpha-Gal / Phase 1
Inhibitory Antibodies (1)
Cat. No. Nom du produit Effect
Pureté Phase
HY-P991396 LY-3321367 Inhibitor 99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (166)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-114409 GB1107 Inhibitor 99.92% Unkown
HY-15934 X-GAL 99.88% Unkown
HY-130208 Thiodigalactoside Inhibitor 99.95% Unkown
HY-137276 5-Bromo-3-indolyl β-D-galactopyranoside Substrate 99.89% Unkown
HY-P2869 β-Galactosidase, E. coli / Unkown
HY-114522 X-alpha-Gal 99.87% Unkown
HY-118135 4-Methylumbelliferyl-α-D-galactopyranoside 99.96% Unkown
HY-155175 TIM-3-IN-2 99.44% Unkown
HY-158742 SBB-Analogue (GL13) Biotin 99.30% Unkown
HY-173496 ST6GAL1-IN-1 Inhibitor 99.33% Unkown
HY-P1723 Spexin 99.12% Unkown
HY-NP0182 Peanut Agglutinin (Biotinylated) / Unkown
HY-P1135 M1145 Agonist 99.96% Unkown
HY-123148 IMB-808 Agonist 99.84% Unkown
HY-DY2002 X-GAL (solution) / Unkown
HY-P1131 M617 Agonist 99.54% Unkown
HY-P1132A Galanin (1-29)(rat, mouse) TFA Agonist 99.70% Unkown
HY-101422 GAL-021 Inhibitor 99.93% Unkown
HY-104004 Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH 99.12% Unkown
HY-NP0138 Peanut Agglutinin (Fluorescein) / Unkown
HY-P3443 Peanut agglutinin / Unkown
HY-103536A Galnon TFA Agonist 98.88% Unkown
HY-P0232 Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 99.08% Unkown
HY-P1765 Galanin (1-19), human 99.25% Unkown
HY-W127769 Rose-β-D-Gal 99.71% Unkown
HY-W145561 Neu5Acα(2-3)Galβ MP glycoside 99.84% Unkown
HY-10678 BMS-687453 Agonist 99.31% Unkown
HY-146808 Galectin-3 antagonist 1 Antagonist 98.95% Unkown
HY-133737 GAL-02-221 Inhibitor 99.87% Unkown
HY-141488 Lacto-N-biose I 98.0% Unkown
HY-W039911 4-Nitrophenyl α-D-galactopyranoside 98.70% Unkown
HY-E70136 Endo-β-Galactosidase / Unkown
HY-P0262A Galantide TFA Antagonist 98.77% Unkown
HY-185060 N-Acetyllactosamine-C2-NH2 / Unkown
HY-RS29497 GAL3ST2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-170510 GB2095 Inhibitor 98.92% Unkown
HY-E70061 alpha-1,3-N-Acetylgalactosaminyltransferase (BgtA) / Unkown
HY-144312 Thiobis-β-Galactose-propyne Inhibitor 99.76% Unkown
HY-153823 UDP-6N3Gal 96.57% Unkown
HY-105327 P11149 Inhibitor 99.23% Unkown
HY-132239 5-Bromo-6-chloro-3-indolyl β-D-Galactopyranoside contains ca. 10% Ethyl Acetate 99.58% Unkown
HY-135378 Atorvastatin ethyl ester 98.16% Unkown
HY-147041A (2S)-Selvigaltin Inhibitor 99.46% Unkown
HY-160694 cBu-Cit-GAL-02-221 Degrader / Unkown
HY-163548 SPP-002 Inhibitor 98.0% Unkown
HY-180467 Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me / Unkown
HY-180467A Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me sodium / Unkown
HY-E70033 D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) / Unkown
HY-E70148 ST6 Gal Sialyltransferase 1 / Unkown
HY-P10010 DB21, Galectin-1 Antagonist Inhibitor / Unkown
HY-P1128 Galanin (swine) Agonist 98.75% Unkown
HY-P1131A M617 TFA 99.38% Unkown
HY-RS13851 ST3GAL6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17282 St6gal1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W415856 β-D-galactose / Unkown
HY-101422A GAL-021 sulfate Inhibitor / Unkown
HY-103536 Galnon Agonist / Unkown
HY-111366 CD12681 Agonist / Unkown
HY-112752 Gal-C4-Chol / Unkown
HY-121542 PPARδ agonist 10 Agonist / Unkown
HY-123708 SNAP 398299 Antagonist / Unkown
HY-130570 β-Gal-NONOate Inhibitor / Unkown
HY-144313 Galectin-3-IN-2 Inhibitor / Unkown
HY-147112 MNP-GAL / Unkown
HY-147209 DC-TEAD3in03 Inhibitor / Unkown
HY-147865 Apoptosis inducer 8 / Unkown
HY-14929S Migalastat-d2 hydrochloride Inhibitor / Unkown
HY-151514 Antituberculosis agent-5 Inhibitor 99.76% Unkown
HY-156232 Gal-GIcNAc-oxazoline / Unkown
HY-158331 Gal-ARV-771 / Unkown
HY-158461 Alpha-Gal standard, 2-AA labelled / Unkown
HY-158462 Alpha-Gal standard, 2-AB labelled / Unkown
HY-163078 C2-Gal-Dox / Unkown
HY-163405 Galectin-3-IN-3 Inhibitor / Unkown
HY-165424 NIR-BG2 Substrate / Unkown
HY-169084 ST-IN-1 Inhibitor / Unkown
HY-172888 SPP-037 Inhibitor / Unkown
HY-173235 Galectin-3-IN-6 Inhibitor / Unkown
HY-175490 RORγ inverse agonist 2 Antagonist / Unkown
HY-177945 MS99-β-Gal Degrader / Unkown
HY-179101 IAN-15B Inhibitor / Unkown
HY-179410 Galectin-3-IN-7 Inhibitor / Unkown
HY-181648 Gal-1-IN-1 Inhibitor / Unkown
HY-182898 Gal-dMor-Gem Inducer / Unkown
HY-D1510 4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside / Unkown
HY-D2990 KSA01 / Unkown
HY-D2992 KSA02 / Unkown
HY-D3096 TPh–PyBz–β–gal / Unkown
HY-D3165 DCM-gal-CF / Unkown
HY-E70053 alpha-1,3-Galactosyltransferase (GTB) / Unkown
HY-E70146 ST3 β-Gal α-2,3-Sialyltransferase 2 / Unkown
HY-E70169 Galactose-3-O-sulfotransferase 2 / Unkown
HY-E70298 ST3 β-Gal α-2,3-Sialyltransferase 1 / Unkown
HY-E70299 ST3 β-Gal α-2,3-Sialyltransferase 5 Inhibitor / Unkown
HY-E70995 Galactose-1-phosphate Uridyltransferase, Galactose-adapted yeast / Unkown
HY-E71300 β-Galactoside α-2,3-sialyltransferase / Unkown
HY-E71393 1-Phosphatidylinositol 4-kinase / Unkown
HY-E71724 α-1,3-Galactosyltransferase, bovine (Recombinant) / Unkown
HY-E72040 Abequosyltransferase / Unkown
HY-N10527 Isoglobotetraose / Unkown
HY-N12016 Fulvotomentoside B / Unkown
HY-N9134 5-O-Methylgenistein Inhibitor / Unkown
HY-NP085 Griffonia Simplicifolia Lectin I Isolectin B4 / Unkown
HY-P1128A Galanin (swine) TFA Agonist / Unkown
HY-P1132 Galanin (1-29)(rat, mouse) Agonist / Unkown
HY-P1133 Galanin (2-29) (rat) Agonist / Unkown
HY-P1135A M1145 TFA Agonist / Unkown
HY-P1560 Allergen Gal d 4 (46-61), chicken Inhibitor / Unkown
HY-P1723A Spexin TFA / Unkown
HY-P5896 Ala5-Galanin (2-11) Agonist / Unkown
HY-RS05238 GAL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05239 GAL3ST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05240 GAL3ST4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05263 GALP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13846 ST3GAL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13847 ST3GAL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13848 ST3GAL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13849 ST3GAL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13850 ST3GAL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13852 ST6GAL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13853 ST6GAL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W145524 Gal[246Bn,3All]-β-SPh / Unkown
HY-W145538 Nonasaccharide Glc4Xyl3Gal2 / Unkown
HY-W145540 Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP / Unkown
HY-W145556 Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP / Unkown
HY-W145558 Galβ(1-4)Glc-β-MP / Unkown
HY-W145559 Gal[236Bn]β(1-4)Glc[236Bn]-β-MP / Unkown
HY-W145594 Gal[26Bn]β(1-4)Glc[236Bn]-β-MP / Unkown
HY-W145607 Galβ(1-3)GalNAc-β-pNP / Unkown
HY-W145609 Neu5Troc[1Me,4789Ac]α(2-3)Gal[26Bn]-β-MP / Unkown
HY-W145620 Gal[246Bn]β(1-4)Glc[236Bn]-β-MP / Unkown
HY-W145621 Gal[2346Bn]-β-SPh / Unkown
HY-W145622 Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP / Unkown
HY-W145655 Gal-β1,3-GalNAc-α1-OBn / Unkown
HY-W145663 Gal-β1,3-GalNAc-β-OMe / Unkown
HY-W154295 Purple-β-D-Gal / Unkown
HY-W357147 4-Trifluoromethylumbelliferyl-ß-D-galactopyranoside / Unkown
HY-W357155 Gal1-β-3GlcNAc-β-PNP / Unkown
HY-W393498 Phenyl 2,4,6-tri-O-acetyl-3-O-allyl-β-D-thiogalactopyranoside / Unkown
HY-W698354 Gal1-β-3GlcNAc1-β-Ome / Unkown
HY-W698379 Gal1-b-4GlcNAc-α-PNP / Unkown
HY-W698547 2-(Acetylamino)-2-deoxy-3-O-α-D-galactopyranosyl-D-galactose / Unkown
HY-W698908 GalNAc1-b-3Gal-α-Ome / Unkown
HY-W699164 Gal1-β-4GlcNAc-β-Bn / Unkown
HY-W699180 Fuc1-α-2Gal1-β-3GlcNAc-β-PNP / Unkown
HY-W706304 Gal1-β-4GlcNAc1-β-6Gal / Unkown
HY-W740650 Migalastat hydrochloride-15N / Unkown
HY-104004R Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Standard) / Unkown
HY-124445 APC0576 Inhibitor / Unkown
HY-135376 Atorvastatin methyl ester 98.76% Unkown
HY-153101 Gal-G2-CNP / Unkown
HY-162789 Galectin-3-IN-5 Inhibitor / Unkown
HY-186237 Fuc(1→2)-Gal(3→1)(C3-amide-C5-biotin)-GalNAc / Unkown
HY-RS17286 Gal Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18209 St3gal4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18441 St3gal3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19435 Ggta1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20651 St3gal1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20652 St6gal2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23737 St6gal1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23741 Gal Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24686 St3gal4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24923 St3gal3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27162 St3gal1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27163 St6gal2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W728096 Migalastat-d5 Inhibitor / Unkown
Inhibitory Antibodies (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P991198 M6903 Ligand 98.81% Unkown
HY-P991369 EBU-141 Inhibitor / Unkown
HY-P992454 S095018 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gal NCBI NCBI:51083