HDAC3/BRD4-IN-1
HDAC3/BRD4-IN-1 (compound 26n) is an inhibitor of HDAC3/BRD4 with an IC50 of 8 nM for HDAC3 (IC50s are 220 nM and 120 nM for HDAC1 and HDAC2, respectively). HDAC3/BRD4-IN-1 has anti-tumor and anti-proliferative effects by upregulating Ac-H3 and downregulating c-Myc. The half-life of HDAC3/BRD4-IN-1 in human liver microsomes is 29.36 min.
For research use only. We do not sell to patients.
- Formula: C31H35N5O4
- Molecular Weight:541.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
HDAC3/BRD4[1]
Chemical Information
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Molecular Weight 541.64
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Formula C31H35N5O4
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SMILES
CC1=NOC(C)=C1C2=CC(CCC3=C(C(NCCCCCCC(NO)=O)=O)N(CC4=CC=CC=C4)N=C35)=C5C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC3/BRD4-IN-1 Related Classifications
HY-170841 Related Classifications
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