BAL-30072
Based on 1 Customer Validation
BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.03%
- CAS 番号: 941285-15-0
- 分子式: C16H18N6O10S2
- 分子量:518.48
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
MIC90: 4 μg/mL (MDR Acinetobacter spp.), 8 μg/mL (MDR P. aeruginosa)[1][2].
化学情報
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CAS 番号 941285-15-0
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性状 Solid
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分子量 518.48
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分子式 C16H18N6O10S2
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Color White to off-white
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SMILES
O=C(N[C@H]1C(C)(C)N(OS(=O)(O)=O)C1=O)/C(C2=CSC(N)=N2)=N/OCC3=CC(C(O)=CN3O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (192.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Page MG, et al. In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli. Antimicrob Agents Chemother. 2010 Jun;54(6):2291-302. [Content Brief]
[2]. Michael Hornsey, et al. In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens. Int J Antimicrob Agents. 2013 Oct;42(4):343-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9287 mL | 9.6436 mL | 19.2871 mL | 48.2179 mL |
| 5 mM | 0.3857 mL | 1.9287 mL | 3.8574 mL | 9.6436 mL | |
| 10 mM | 0.1929 mL | 0.9644 mL | 1.9287 mL | 4.8218 mL | |
| 15 mM | 0.1286 mL | 0.6429 mL | 1.2858 mL | 3.2145 mL | |
| 20 mM | 0.0964 mL | 0.4822 mL | 0.9644 mL | 2.4109 mL | |
| 25 mM | 0.0771 mL | 0.3857 mL | 0.7715 mL | 1.9287 mL | |
| 30 mM | 0.0643 mL | 0.3215 mL | 0.6429 mL | 1.6073 mL | |
| 40 mM | 0.0482 mL | 0.2411 mL | 0.4822 mL | 1.2054 mL | |
| 50 mM | 0.0386 mL | 0.1929 mL | 0.3857 mL | 0.9644 mL | |
| 60 mM | 0.0321 mL | 0.1607 mL | 0.3215 mL | 0.8036 mL | |
| 80 mM | 0.0241 mL | 0.1205 mL | 0.2411 mL | 0.6027 mL | |
| 100 mM | 0.0193 mL | 0.0964 mL | 0.1929 mL | 0.4822 mL |