Cibinetide acetate
Based on 6 publication(s) in Google Scholar
Cibinetide (ARA290) acetate is an erythropoietin (EPO) derivative that acts as a specific agonist of the erythropoietin/CD131 heteroreceptor. ICibinetide acetate can be used in the research of neurological disorders.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C51H84N16O21.xC2H4O2
- 分子量:1257.31 (free base)
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Cibinetide acetate
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IHC
生物活性
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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分子量 1257.31 (free base)
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分子式 C51H84N16O21.xC2H4O2
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SMILES
OC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCC(N1)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)CO)=O)CO)=O.CC(O)=O.[x]
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別名
ARA290 acetate
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配列
{Glp}-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
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シーケンスの短縮
{Glp}-EQLERALNSS
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (6)
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Journal Impact Factor
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Most Recent
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CNS Neurosci Ther
Erythropoietin-derived peptide ARA290 mediates brain tissue protection through the β-common receptor in mice with cerebral ischemic stroke. [Abstract]2024 Mar;30(3):e14676. PMID: 38488446 -
Immunology
EPOR activation attenuates colitis via enhancing LC3B-dependent apoptotic cell clearance. [Abstract]2025 Sep;176(1):33-48. PMID: 37204242 -
Int J Mol Sci
2024 Mar 29;25(7):3854. PMID: 38612664 -
Toxicol In Vitro
An engineered non-erythropoietic erythropoietin-derived peptide, ARA290, attenuates doxorubicin induced genotoxicity and oxidative stress. [Abstract]2020 Aug;66:104864. PMID: 32335150
Cibinetide acetate purchased from MedChemExpress. Usage Cited in: Toxicol In Vitro. 2020 Aug;66:104864. [Abstract]
Representative photomicrographs demonstrate the results of the TUNEL assay. Alterations in apoptotic cells are assessed using the ratio of green fluorescence. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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純度とドキュメンテーション
参考文献
[1]. Hache G, et al. ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability. Shock. 2016 Oct;46(4):390-7. [Content Brief]
[2]. Carole Muller, et al. ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats. Mol Med. 2015; 21(1): 969–978. [Content Brief]
[3]. Chen H, et al. Therapeutic effects of nonerythropoietic erythropoietin analog ARA290 in experimental autoimmune encephalomyelitis rat. J Neuroimmunol. 2014 Mar 15;268(1-2):64-70. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Cibinetide acetate 関連分類
HY-P0168A 関連分類
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