Asns - asparagine synthetase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27053

Summary

Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity and identical protein binding activity. Predicted to be involved in several processes, including asparagine biosynthetic process; cellular response to glucose starvation; and positive regulation of mitotic cell cycle. Predicted to act upstream of or within cellular amino acid biosynthetic process and glutamine metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)). [provided by Alliance of Genome Resources, Apr 2022]

Asns Products (6)

mRNA Protein Name
NM_001410605.1 NP_001397534.1 asparagine synthetase [glutamine-hydrolyzing] isoform a
NM_001410606.1 NP_001397535.1 asparagine synthetase [glutamine-hydrolyzing] isoform a
NM_001410607.1 NP_001397536.1 asparagine synthetase [glutamine-hydrolyzing] isoform a
NM_001410608.1 NP_001397537.1 asparagine synthetase [glutamine-hydrolyzing] isoform a
NM_001410609.1 NP_001397538.1 asparagine synthetase [glutamine-hydrolyzing] isoform b
NM_012055.5 NP_036185.1 asparagine synthetase [glutamine-hydrolyzing] isoform a
Protein Preferred Names Protein Names

asparagine synthetase [glutamine-hydrolyzing]

  • glutamine-dependent asparagine synthetase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (7)
Cat. No. Nom du produit Effect
Pureté Rare Diseases
HY-132254 Sacituzumab govitecan Inhibitor 99.13% Unkown
HY-132254A Sacituzumab govitecan (solution) Inhibitor 99.19% Unkown
HY-N0667 L-Asparagine 99.78% Unkown
HY-W017443 L-Asparagine monohydrate 99.77% Unkown
HY-14874 Topiroxostat Inhibitor 99.06% Unkown
HY-123319 Antofloxacin hydrochloride Inhibitor / Unkown
HY-123319A Antofloxacin Inhibitor / Unkown

Clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit Effect
Pureté Phase
HY-103018 Gusacitinib Inhibitor 99.63% Phase 2
HY-136579 ASN007 Inhibitor 99.48% Phase 1
HY-160196 HC-7366 Inhibitor 99.58% Phase 1
HY-164457 ASN-001 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (131)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-128946 CL2A-SN-38 99.97% Unkown
HY-128923 SKF-34288 hydrochloride Inhibitor 98.61% Unkown
HY-W002327 Fmoc-Asn(Trt)-OH 99.96% Unkown
HY-136626 Z-Ala-Ala-Asn-AMC 99.28% Unkown
HY-108625 SHA 68 Antagonist 99.84% Unkown
HY-112205A RR-11a analog Inhibitor 99.12% Unkown
HY-164668 ADC Control Human IgG1-SN-38 97.53% Unkown
HY-P4385 (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) Antagonist 99.77% Unkown
HY-N0667S2 L-Asparagine-15N2 monohydrate 99.95% Unkown
HY-139147 iHCK-37 Inhibitor 99.52% Unkown
HY-175282 ASX-173 98.47% Unkown
HY-114174 Fmoc-Ala-Glu-Asn-Lys-NH2 99.55% Unkown
HY-136579A ASN007 benzenesulfonate Inhibitor 99.72% Unkown
HY-W010378 D-Asparagine 98.0% Unkown
HY-156586 Egalognastat Inhibitor 99.03% Unkown
HY-N9446 H-Asn(glcnac-beta-D)-OH 98.65% Unkown
HY-P1341 OXA(17-33) 97.48% Unkown
HY-P1043A NGR peptide Trifluoroacetate 98.91% Unkown
HY-N0667S3 L-Asparagine-13C4 monohydrate 98.9% Unkown
HY-W009085 Fmoc-Asn-OH 99.19% Unkown
HY-W017443S L-Asparagine-13C4,15N2 monohydrate 98.0% Unkown
HY-111323 ASN06917370 99.23% Unkown
HY-128111 ASN02563583 Activator 99.21% Unkown
HY-B1803A Tracazolate hydrochloride Modulator 99.24% Unkown
HY-E70068 Endo-β-N-acetylglucosaminidase (Endo S) / Unkown
HY-N0667S5 L-Asparagine-d3 hydrate 99.64% Unkown
HY-113667 ASN04885796 Activator 99.40% Unkown
HY-108585A VU591 Inhibitor 98.81% Unkown
HY-148393 G0 N-glycan-Asn 99.95% Unkown
HY-P11200 γ-Glu-Asn 98.12% Unkown
HY-W013330 3′-Deoxyguanosine 97.0% Unkown
HY-P4279 Ovalbumin (154-159) Inhibitor 99.18% Unkown
HY-125028 Hck-IN-1 Inhibitor 98.10% Unkown
HY-150242A Cbz-Ala-Ala-Asn TFA 99.54% Unkown
HY-150579 Keap1-Nrf2-IN-13 Inhibitor 96.77% Unkown
HY-162238 OSM-S-106 Inhibitor 99.34% Unkown
HY-150787 BMS-986339 99.74% Unkown
HY-128128 ASN04421891 Modulator 99.00% Unkown
HY-131092A H-Asn-Arg-OH diTFA 99.83% Unkown
HY-175282A (2S,3R,4S)-ASX-173 Control 99.29% Unkown
HY-P10485 Glp-Asn-Pro-AMC 99.26% Unkown
HY-P1809A Velmupressin acetate Agonist 99.47% Unkown
HY-P1962 β-Secretase inhibitor Inhibitor 98.06% Unkown
HY-W010378R D-Asparagine (Standard) 99.90% Unkown
HY-108585 VU591 hydrochloride Inhibitor ≥99.0% Unkown
HY-129360A Ala-Ala-Asn-PAB TFA / Unkown
HY-141464 Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH 95.03% Unkown
HY-156314 ASN 07115873 Inhibitor 98.76% Unkown
HY-172473 DSPE-PEG2000-NGR 95.0% Unkown
HY-176977 Exatecan-mpGly-Asn-Asn-(βAla) 96.74% Unkown
HY-180467 Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me / Unkown
HY-180467A Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me sodium / Unkown
HY-78162 cis-3-Hydroxyproline Substrate 95.0% Unkown
HY-N0667S L-Asparagine-13C4,15N2,d8 99% Unkown
HY-N0667S1 L-Asparagine-15N2,d8 99.94% Unkown
HY-P3882 Fmoc-Ala-Glu-Gln-Lys-NH2 99.26% Unkown
HY-W008233 Z-Asn-OH 98.76% Unkown
HY-W017443S1 L-Asparagine-amide-15N monohydrate 99.80% Unkown
HY-148389 Disialo-Asn 98.04% Unkown
HY-W017443S2 L-Asparagine-13C4,15N2,d3 monohydrate 99.90% Unkown
HY-W142294 Ac-D-Asn-OH / Unkown
HY-P1809 Velmupressin Agonist / Unkown
HY-P1810 c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm Agonist / Unkown
HY-103018A Gusacitinib hydrochloride Inhibitor / Unkown
HY-P1043 NGR peptide 99.73% Unkown
HY-103018S Gusacitinib-d4 / Unkown
HY-113761 ASN03576800 Inhibitor 99.61% Unkown
HY-122179 NUCC-555 Antagonist / Unkown
HY-128947 CL2 Linker / Unkown
HY-129360 Ala-Ala-Asn-PAB / Unkown
HY-129361 Fmoc-Ala-Ala-Asn-PABC-PNP / Unkown
HY-130933 Fmoc-Ala-Ala-Asn(Trt)-OH 99.80% Unkown
HY-131463 ASN-1377642 Antagonist / Unkown
HY-136733 Ac-DNLD-CHO Inhibitor / Unkown
HY-139245 MC-Ala-Ala-Asn-PAB / Unkown
HY-141149 Fmoc-PEG4-Ala-Ala-Asn-PAB / Unkown
HY-141150 Azido-PEG5-Ala-Ala-Asn-PAB / Unkown
HY-141151 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB / Unkown
HY-144628 Fmoc-Asn-Pro-Val-PABC-PNP 99.34% Unkown
HY-144629 Asn-Pro-Val-PABC-MMAE TFA / Unkown
HY-144630 diSPhMC-Asn-Pro-Val-PABC-MMAE / Unkown
HY-148031 MC-Ala-Ala-Asn-PAB-PNP / Unkown
HY-148392 Neu5Gcα(2-6) N-Glycan-Asn / Unkown
HY-149360 P-gb-IN-1 Inhibitor / Unkown
HY-149825 MTHFD2-IN-1 Inhibitor / Unkown
HY-149826 MTHFD2-IN-2 Inhibitor / Unkown
HY-149827 MTHFD2-IN-3 Inhibitor / Unkown
HY-149828 MTHFD2-IN-4 Inhibitor / Unkown
HY-149828A MTHFD2-IN-4 sodium Inhibitor / Unkown
HY-151146 (1R,3S)-THCCA-Asn Inhibitor / Unkown
HY-172472 DSPE-PEG1000-NGR / Unkown
HY-172473A DSPE-PEG3400-NGR / Unkown
HY-172474 DSPE-PEG5000-NGR / Unkown
HY-174223 α-Glucosidase-IN-90 Inhibitor / Unkown
HY-183362 Antileishmanial agent-42 Inhibitor / Unkown
HY-185461 Mc-Asn-Asn-E104 Agonist / Unkown
HY-185462 Mc-Asn-Asn 99.84% Unkown
HY-187399A DOPE-PEG2000-NGR / Unkown
HY-189127 Antibacterial agent 373 Inhibitor / Unkown
HY-E71264 β-Acetylglucosaminidase 18A, Bacteroides thetaiotaomicron / Unkown
HY-N0667S4 L-Asparagine-4-13C monohydrate / Unkown
HY-N0667S7 L-Asparagine-13C4,15N2 / Unkown
HY-P11408 [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) Agonist / Unkown
HY-P11620 H-Asn-Pro-Glu-Tyr(PO3H2)-OH / Unkown
HY-P1610 Asudemotide Inducer / Unkown
HY-P2212 (Asn1,Val5)-Angiotensin II / Unkown
HY-P2397 Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH / Unkown
HY-P2401 Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH / Unkown
HY-P3220 [D-Asn5]-Oxytocin Activator / Unkown
HY-P3615 [Asn18] Endothelin-1 (swine, human) Agonist / Unkown
HY-P3716 H(-Asn-Pro-Asn-Ala)2-OH / Unkown
HY-P4019 Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 / Unkown
HY-P4407 (D-Asn28)-Exenatide Control / Unkown
HY-P4919 Mca-SEVNLDAEFK(Dnp) / Unkown
HY-P5415 DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS / Unkown
HY-RS01098 ASNS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W017443S3 L-Asparagine-15N2,d3 monohydrate / Unkown
HY-W017443S4 L-Asparagine-13C4 / Unkown
HY-W091365 Boc-Asn(Xan)-OH / Unkown
HY-W845197 L-Asparagine-15N2 / Unkown
HY-118731 TNK-6123 Activator / Unkown
HY-129286 ASN 05397535 / Unkown
HY-131092 H-Asn-Arg-OH / Unkown
HY-141152 Azido-PEG4-Ala-Ala-Asn(Trt)-PAB / Unkown
HY-141153 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP / Unkown
HY-151829 Fmoc-L-Asn(EDA-N3)-OH / Unkown
HY-157338 NHS-Ala-Ala-Asn-active metabolite Inhibitor / Unkown
HY-RS19117 Asns Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25607 Asns Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W002327S Fmoc-Asn(Trt)-OH-13C4,15N2 96.9% Unkown
HY-W173361 CBP/p300-IN-24 Inhibitor / Unkown
Inhibitory Antibodies (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P992184 Anti-5T4 scFv-Fc Antibody / Unkown
HY-P991497 ASN-500 Inhibitor / Unkown
HY-P991745 Anti-Mouse CCR2 Antibody (C2Mab-6) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asns NCBI NCBI:440