2. Gene
  3. EP300 - E1A binding protein p300 Gene

EP300 - E1A binding protein p300 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 100684945 | Gene type: protein coding

About EP300

Primary_assembly 10: 24,824,097-24,903,879 reverse strand.ROS_Cfam_1.0:CM025109.1

This gene has 4 transcripts (splice variants), 286 orthologues and 1 paralogue.

EP300 Products(2)

mRNA Protein Name
XM_038679753.1 XP_038535681.1 histone acetyltransferase p300 isoform X1
XM_038679754.1 XP_038535682.1 histone acetyltransferase p300 isoform X2

EP300 Protein Structure

COG5651

COG5651: cl35037 (49 - 217)

zf-TAZ

zf-TAZ: pfam02135 (347 - 414)

KIX

KIX: pfam02172 (566 - 646)

Atrophin-1

Atrophin-1: cl38111 (641 - 997)

Bromo_cbp_like

Bromo_cbp_like: cd05495 (1053 - 1160)

RING_CBP-p300

RING_CBP-p300: cd15802 (1172 - 1244)

PHD_p300

PHD_p300: cd15646 (1245 - 1279)

HAT_KAT11

HAT_KAT11: pfam08214 (1308 - 1614)

ZZ_CBP

ZZ_CBP: cd02337 (1670 - 1710)

zf-TAZ

zf-TAZ: pfam02135 (1737 - 1805)

Med15

Med15: cl26621 (1994 - 2365)

Creb_binding

Creb_binding: pfam09030 (1996 - 2102)

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  • 2430 a.a.
Protein Preferred Names Protein Names

histone acetyltransferase p300

Related Agents

Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-N0005 Curcumin 98.84% Phase 4
HY-134964 CTB 99.93% Phase 4
HY-111784 Inobrodib Inhibitor 99.95% Phase 2
HY-111422 PLX51107 Inhibitor 99.98% Phase 2
HY-136938 NEO2734 Inhibitor 99.63% Phase 1
Pre-clinical Phase
Bioactive Molecules (142)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107455 A-485 Inhibitor 99.87% Unkown
HY-13823 C646 99.88% Unkown
HY-14428 ICG-001 99.86% Unkown
HY-15826 SGC-CBP30 Inhibitor 99.83% Unkown
HY-15887 MG 149 99.60% Unkown
HY-N2020 Anacardic Acid Inhibitor 98.49% Unkown
HY-110127 NU9056 98.81% Unkown
HY-134582 dCBP-1 Inhibitor 99.37% Unkown
HY-107569 Garcinol 98.85% Unkown
HY-138536 PROTAC CBP/P300 Degrader-1 Inhibitor 99.97% Unkown
HY-W105310A Croconic acid disodium 99.98% Unkown
HY-124696 PU139 Inhibitor 99.51% Unkown
HY-136285 CPI-1612 Inhibitor 99.75% Unkown
HY-116673 TTK21 Activator 99.39% Unkown
HY-W013274 CPTH2 99.82% Unkown
HY-158113 CBPD-409 Degrader 99.38% Unkown
HY-N0005R Curcumin (Standard) 98.01% Unkown
HY-138539 CBP/p300 ligand 2 99.39% Unkown
HY-145765 JQAD1 98.24% Unkown
HY-124960 CTPB Activator ≥99.0% Unkown
HY-100482 CPI-637 Inhibitor 99.94% Unkown
HY-100726 GNE-272 Inhibitor 99.60% Unkown
HY-19541 I-CBP112 98.43% Unkown
HY-N2345 Procyanidin B3 Inhibitor 99.92% Unkown
HY-154984 JET-209 Degrader 98.07% Unkown
HY-10593 IQ 1 Modulator 99.13% Unkown
HY-100671 L002 Inhibitor 99.44% Unkown
HY-100734 Histone Acetyltransferase Inhibitor II Inhibitor 98.70% Unkown
HY-161369 CBPD-268 Degrader 99.23% Unkown
HY-P10238 MYBMIM Inducer 99.96% Unkown
HY-152241 DS-9300 Inhibitor 99.83% Unkown
HY-173552 TCIP3 Inhibitor 99.30% Unkown
HY-N0005S Curcumin-d6 99.78% Unkown
HY-101125 L-Moses Inhibitor 99.97% Unkown
HY-128876 CBP/p300-IN-3 Inhibitor 98.01% Unkown
HY-115539 Windorphen Inhibitor 99.75% Unkown
HY-131035 Lys-CoA TFA Inhibitor 98.52% Unkown
HY-17663 KMR-206 98.86% Unkown
HY-141466A Crotonyl-CoA tetrasodium Substrate 97.85% Unkown
HY-100697 TPOP146 Inhibitor 98.94% Unkown
HY-111420 CBP/p300-IN-1 Inhibitor 99.71% Unkown
HY-139108 DCH36_06 99.19% Unkown
HY-RS04405 EP300 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-134591 Thalidomide-NH-PEG4-COOH Inducer 96.65% Unkown
HY-147008 XP-524 Inhibitor 98.02% Unkown
HY-125847 Salvianolic acid F 99.50% Unkown
HY-147290 NSC 694623 Inhibitor 99.53% Unkown
HY-161483 CBP/p300 ligand 3 Inhibitor 98.82% Unkown
HY-132197 CBP/p300-IN-12 Inhibitor 99.72% Unkown
HY-120290 PU141 Inhibitor 99.96% Unkown
HY-139148 UMB298 Inhibitor 99.28% Unkown
HY-W877997 Pomalidomide 5'-pip-acid / Unkown
HY-141546 Pocenbrodib Inhibitor 98.49% Unkown
HY-134592 Piperidine-GNE-049-N-Boc 98.48% Unkown
HY-136920 CBP/p300-IN-8 Inhibitor 99.94% Unkown
HY-112359 C-82 Inhibitor 99.91% Unkown
HY-146277A CBP/p300-IN-19 hydrochloride Inhibitor 99.00% Unkown
HY-162259 QC-182 Degrader 98.94% Unkown
HY-128875 CBP/p300-IN-10 Inhibitor 99.74% Unkown
HY-139707 PROTAC CBP/P300 Degrader-3 Degrader 98.55% Unkown
HY-110263 EML 425 Inhibitor 98.04% Unkown
HY-174866 BT-O2C Inhibitor / Unkown
HY-RS04406 Ep300 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-101125A L-Moses dihydrochloride Inhibitor 99.38% Unkown
HY-100132 CBP/p300-IN-5 Inhibitor ≥97.0% Unkown
HY-101125B D-Moses Control / Unkown
HY-136285A (R,R)-CPI-1612 Control 99.49% Unkown
HY-145386 (S,S)-CPI-1612 Control 99.88% Unkown
HY-147261 B026 Inhibitor / Unkown
HY-151812 CBP/p300-IN-20 Inhibitor 98.03% Unkown
HY-153768 KAT modulator-1 Modulator 98.0% Unkown
HY-168201 MJP6412 Degrader 95.90% Unkown
HY-134621 P300-IN-1 Inhibitor / Unkown
HY-143443 DS17701585 Inhibitor / Unkown
HY-W013274A CPTH2 hydrochloride / Unkown
HY-114510 PRMT/HKMT-IN-1 / Unkown
HY-121009 CCT077791 Inhibitor / Unkown
HY-121089 P300-IN-5 Inhibitor / Unkown
HY-122081 CPI-644 Inhibitor / Unkown
HY-124722 OHM1 Inhibitor / Unkown
HY-128362 Ep300/CREBBP-IN-8 Inhibitor / Unkown
HY-128363 Ep300/CREBBP-IN-2 Inhibitor / Unkown
HY-128364 Ep300/CREBBP-IN-3 Inhibitor / Unkown
HY-128367 Ep300/CREBBP-IN-4 Inhibitor / Unkown
HY-128761 CBP/p300-IN-2 Inhibitor / Unkown
HY-139804 CTK7A Inhibitor / Unkown
HY-139861 CBP/p300-IN-14 Inhibitor / Unkown
HY-143339 CBP/p300-IN-15 Inhibitor / Unkown
HY-143440 CBP/p300-IN-16 Inhibitor / Unkown
HY-143441 CBP/p300-IN-17 Inhibitor / Unkown
HY-143442 CBP/p300-IN-18 Inhibitor / Unkown
HY-146277 CBP/p300-IN-19 Inhibitor / Unkown
HY-146445 P300 bromodomain-IN-1 Inhibitor / Unkown
HY-155229 CBP/p300-IN-21 Inhibitor / Unkown
HY-159587 P300-IN-4 Inhibitor / Unkown
HY-160261S EP300/CBP-IN-2 Inhibitor / Unkown
HY-161250 Pomalidomide-NH-PEG6-amide-C2-CPI-1612 / Unkown
HY-161494 XYD190 Inhibitor / Unkown
HY-161495 CBP/p300 ligand 4 Inhibitor / Unkown
HY-161498 XYD198 Inhibitor / Unkown
HY-161710 XYD129 Degrader / Unkown
HY-161958 dCE-2 / Unkown
HY-161959 EP300/CBP ligand 1 / Unkown
HY-161960 EP300/CBP ligand 2 / Unkown
HY-162128 Antitumor agent-130 Inhibitor / Unkown
HY-164005 CBP/EP300 bromodomain receptor-IN-1 Inhibitor / Unkown
HY-165413 KST012174 hydrochloride Inhibitor / Unkown
HY-168148S CZL-046 Inhibitor / Unkown
HY-168463 Y16524 Inhibitor / Unkown
HY-168464 Y16526 Inhibitor / Unkown
HY-173641 MNN-02-155 / Unkown
HY-174868 iP300w Inhibitor / Unkown
HY-176251 CBP/p300-IN-22 Inhibitor / Unkown
HY-179498 ROCK2-IN-13 / Unkown
HY-179657 PROTAC MLT Degrader 1 / Unkown
HY-180804 CZL-077 Inhibitor / Unkown
HY-181261 PROTAC CBP/P300 Degrader-2 / Unkown
HY-181669 P300-IN-6 Inhibitor / Unkown
HY-181758 PROTAC CBP/p300/BRD4 Degrader-1 / Unkown
HY-181759 CBP/p300/BRD4 ligand-1 Ligand / Unkown
HY-181852 CBP/p300 ligand 10 Degrader / Unkown
HY-181957 KB528 / Unkown
HY-183251 PROTAC p300 degrader-1 Degrader / Unkown
HY-183802 PROTAC CBP/P300 Degrader-4 Degrader / Unkown
HY-183817 GNE-781-COOH Degrader / Unkown
HY-183818 CRBN ligand-903 / Unkown
HY-183819 CRBN ligand-903-trans-1,4-cyclohexanediamine-Boc / Unkown
HY-185009 GSK702 / Unkown
HY-186064 CBP/p300 ligand-Linker Conjugate 3 / Unkown
HY-RS04407 Ep300 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W197205 SL010110 / Unkown
HY-W585171 CRBN ligand-896 / Unkown
HY-123009 KCN1 Inhibitor / Unkown
HY-123758 XDM-CBP Inhibitor / Unkown
HY-141466 Crotonyl-CoA Substrate / Unkown
HY-160260 EP300/CBP-IN-1 Inhibitor / Unkown
HY-161711 CBP/p300 ligand 5 / Unkown
HY-161961 Thalidomide-NH-C10-Boc / Unkown
HY-166309 Crotonyl-CoA tetralithium Substrate / Unkown
HY-19541A I-CBP112 hydrochloride Inhibitor / Unkown
HY-N0005S1 Curcumin-d3 / Unkown
HY-W173361 CBP/p300-IN-24 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens EP300 NCBI NCBI:2033
Mus musculus EP300 NCBI NCBI:328572