IL5 - interleukin 5 Gene

Also Known as EDF; TRF; IL-5

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 3567

About IL5

Cytogenetic location: 5q31.1 Genomic coordinates (GRCh38): 5:132,541,445-132,556,815 (from NCBI)

This gene has 3 transcripts (splice variants) and 91 orthologues. Low expression observed in reference dataset.

Summary

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]

IL5 Products (4)

mRNA	Protein	Name
NM_000879.3	NP_000870.1	interleukin-5 precursor
XM_005271988.5	XP_005272045.1	interleukin-5 isoform X1
XM_047417148.1	XP_047273104.1	interleukin-5 isoform X3
XM_011543373.4	XP_011541675.1	interleukin-5 isoform X2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables cytokine activity	IDA IDA: Inferred from direct assay	33099778	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	1495999	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in interleukin-5-mediated signaling pathway	IDA IDA: Inferred from direct assay	33099778	GOA
involved in positive regulation of podosome assembly	IDA IDA: Inferred from direct assay	15220135	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in extracellular region	IDA IDA: Inferred from direct assay	20041150	GOA
is active in extracellular space	IDA IDA: Inferred from direct assay	33099778	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IL5 Protein Structure

IL5

0
100
134 a.a.

Protein Preferred Names	Protein Names
interleukin-5	B-cell differentiation factor I T-cell replacing factor colony-stimulating factor, eosinophil eosinophil differentiation factor

IL5 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	IL5	P05113	IL5RA	Homo sapiens	Q01344-2	X-Ray Diffraction	22153509
Intra	IL5	P05113	IL5RA	Homo sapiens	Q01344-2	GMS	22153509
Intra	IL5	P05113	IL5RA	Homo sapiens	Q01344-2	SPR	22153509

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant IL5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7043	IL-5 Protein, Human	P05113-1 (I20-S134)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P7043A	IL-5 Protein, Human (CHO)	P05113-1 (I20-S134)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70612	IL-5 Protein, Human (HEK293, His)	P05113-1 (I20-S134)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72387	IL-5 Protein, Human (Biotinylated, HEK293, His-Avi)	P05113-1 (I20-S134)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700131AF	Animal-Free IL-5 Protein, Human (His)	P05113-1 (I20-S134)	≥ 95%, as determined by reducing SDS-PAGE.

IL5 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P810893	IL-5 Antibody	WB, IHC-P	Human, Mouse, Rat
HY-P85018	IL-5 Antibody (YA4710)	ELISA	Human

Related Diseases

Diseases	Alias
Candidiasis	Systemic Candidiasis Invasive Candidiasis Disseminated Candidiasis Systemic Candida Infections Candidiasis, Invasive
Bullous Pemphigoid	Benign Pemphigus Senile Dermatitis Herpetiformis Old Age Pemphigus Parapemphigus Pemphigoid Pemphigoid Bullous Pemphigoid, Bullous
Celiac Disease 1	Celiac Disease Coeliac Disease Celiac Sprue Celiac Disease, Susceptibility To Gluten-Sensitive Enteropathy Nontropical Sprue Sprue CELIAC1 Celiac Disease, Susceptibility To, 1 Celiac Sprue 1 Celiac Sprue, Susceptibility To, 1 Gluten-Sensitive Enteropathy 1 Gluten-Sensitive Enteropathy, Susceptibility To, 1 Idiopathic Steatorrhea Cœliac Disease Gluten Intolerance Gluten-Induced Enteropathy Gluten Enteropathy Celiac Disease, Susceptibility To, Type 1 Childhood Celiac Disease Coeliac Rickets Gee Disease Gee-Herter Disease Heubner-Herter Disease Idiopathic Steatorrhoea Thaysen'S Disease Herter Gee Syndrome
Fruit Allergy	Allergy To Fruit
Pollen Allergy	Hay Fever
Autoimmune Disease Of Blood
Chronic Conjunctivitis
Tetanus	Lockjaw Clostridial Tetanus Infection Due To Clostridium Tetani Lock-Jaw
Psoriasis
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma	Cutaneous T-Cell Lymphoma Cutaneous T Cell Lymphoma Lymphoma, T-Cell, Cutaneous Ctcl Lymphoma T-Cell Cutaneous
Cefaclor Allergy	Ceclor Allergy Cephaclor Allergy
Ceftriaxone Allergy	Rocephin Allergy
Eosinophilic Pneumonia	Pneumonia, Eosinophilic Pulmonary Eosinophilia Asthmatic Pulmonary Eosinophilia Pneumonia Eosinophilic Simple Pulmonary Eosinophilia Eosinophilic Asthma
Bronchiolitis
Common Cold	Acute Coryza Acute Nasopharyngitis Acute Rhinitis Acute Viral Rhinopharyngitis Nasopharyngitis - Acute Nasopharyngitis, Acute Rhino-Sinusitis Rhinosinusitis Common Colds Acute Infective Rhinitis Cold Coryza Head Cold Infective Nasopharyngitis Rhinopharyngitis Acute Nasal Catarrh Infective Rhinitis Acute Nasopharyngeal Catarrh Infective Nasopharyngitis Nos Nasopharyngitis Nos Epipharyngitis Mucositis Nos Inflammatory Disease Of Mucous Membrane Mucosal Inflammation
Parasitic Ectoparasitic Infectious Disease	Ectoparasitic Infestations Ectoparasitism
Echinococcosis	Hydatidosis Echinococcal Disease Echinococcosis Of Liver Hepatic Echinococcosis Hydatid Disease Liver Echinococcus Pulmonary Echinococcosis Hydatids Echinococcosis, Hepatic Echinococcosis, Pulmonary Unilocular Echinococcosis Echinococcus Disease Echinococcus Granulosus Infection Echinococcus Multilocularis Infection Dog Tapeworm Infection Echinococcus Granulosus Infestation Echinococciasis Cystic Echinococcosis
Gastroenteritis	Cholera Morbus Infectious Colitis, Enteritis And Gastroenteritis Enteritis Due To Astrovirus Rotaviral Gastroenteritis Viral Gastroenteritis Due To Rotavirus
Endomyocardial Fibrosis	Becker'S Disease Obscure African Cardiomyopathy African Endomyocardial Fibrosis Endomyocardial Sclerosis EMF Becker Muscular Dystrophy
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Bullous Skin Disease	Skin Diseases Bullous Skin Diseases, Bullous
Intermittent Asthma
Aspergillosis	Aspergillosis, Susceptibility To Infection Due To Aspergillus Aspergilloma Aspergillus Nodule Simple Aspergilloma Aspergillus Aspergillus Flavus Infection Aspergillus Fumigatus Infection Aspergillus Infection Infection By Aspergillus Fumigatus Intracavitary Aspergillus Fungus Ball Aspergillus Terreus
Milk Allergy	Milk Allergic Reaction Milk Hypersensitivity Allergy Milk
Metal Allergy
Drug Allergy	Allergy Drug Drug Allergies
Latex Allergy
T2-Low Asthma	Type 2 Low Endotype
Neuromyelitis Optica	Devic Disease Devic Syndrome Devic'S Disease Neuromyelitis Optica Spectrum Disorder Devic'S Syndrome Devic'S Neuromyelitis Optica Nmo Nmo Spectrum Disorder Neuromyelitis Optica Spectrum Disorders Devic Neuromyelitis Optica Optic-Spinal Ms Opticospinal Ms Nmosd Opticospinal Multiple Sclerosis Devic Ophthalmoneuromyelitis Optic Neuromyelitis Optic Neuroencephalomyelopathy Nmo - [Neuromyelitis Optica] Optic Neuritis With Demyelination
Eosinophilic Gastritis	Eosinophilic Enteropathy
Status Asthmaticus	Asthma With Status Asthmaticus Severe Asthma Attack
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Primary Bacterial Infectious Disease
Ascaris Lumbricoides Infection	Ascariasis Ascaris Lumbricoides Infection, Susceptibility To Ascariasis, Susceptibility To Ascariasis - Roundworm Infection Due To Ascaris Lumbricoides Ascaridiasis Roundworm Infection Ascaridia Ascaridiosis Ascaridosis Ascariosis Ascaris Ascaris Lumbricoides Infestation Ascaris Infection Infection By Ascaridia
Allergic Rhinitis	Hay Fever Allergic Rhinitis, Susceptibility To ALRH Atopic Rhinitis Seasonal Allergic Rhinitis Non-Seasonal Allergic Rhinitis Perenial Allergic Rhinitis Pollenosis Rhinitis Allergic Seasonal Rhinitis, Allergic, Perennial Allergic Rhinitis, Cause Unspecified Pollinosis Pollen Allergy Allergy Nos Due To Pollen Summer Catarrh Other Seasonal Allergic Rhinitis
Nose Disease	Nose Diseases Disorder Of The Nose Nasal Disorder Abnormality Of The Nose
Paranasal Sinus Disease	Paranasal Sinus Diseases Disorder Of Nasal Sinus
Toxocariasis	Toxocara Infection Visceral Larva Migrans Larva Migrans, Visceral Infection By Toxascaris Larva Migrans Visceral Larva Migrans Visceralis Toxocaral Visceral Larva Migrans Visceral Larva Migrans Syndrome Toxocara Infestation
Hypereosinophilic Syndrome	Eosinophilia HES Eosinophilic Leukocytosis Hypereosinophilic Syndrome, Idiopathic Idiopathic Hypereosinophilic Syndrome Disseminated Eosinophilic Collagen Disease Eosinophilic Disorder Disorders With Increased Eosinophil Counts
Cercarial Dermatitis	Swimmer'S Itch Cutaneous Schistosomiasis Sea Bather'S Eruption Clam-Digger'S Itch Rice-Paddy Itch Sea Bather'S Itch Sawah Itch Schistosomal Cercarial Dermatitis
Folliculitis
Integumentary System Disease
Respiratory Syncytial Virus Infectious Disease	Respiratory Syncytial Virus Infections Respiratory Syncytial Virus Infection
Eosinophilic Meningitis	Eosinophilic Meningoencephalitis Due To Angiostrongylus Cantonensis
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary
Enterobiasis	Oxyuriasis Pinworm Infection Enterobius Vermicularis Infection Threadworm Infection Oxyuris Vermicularis Infection Enterobiosis Pinworm Pinworm Disease Seatworm Infection Enterobiasis Threadworm Pinworm Infestation Seatworm
Conjunctival Disease	Conjunctival Diseases Conjunctival Disorder
Autoimmune Disease Of Musculoskeletal System
Bronchial Disease	Bronchial Diseases Bronchial Disorders Bronchial Spasm
Crohn'S Disease	Crohn Disease Pediatric Crohn'S Disease Regional Enteritis Crohn'S Disease Of Large Bowel Enteritis, Granulomatous Crohn'S Disease Of Colon Granulomatous Colitis Colitis, Granulomatous Crohn'S Enteritis Enteritis, Regional Enteritis Ileitis Adenoviral Enteritis Acute Gastroenteropathy Due To Norwalk Agent Viral Gastroenteritis Due To Norwalk Agent Winter Vomiting Epidemic Winter Vomiting Disease Small Round Structured Virus Enteritis Epidemic Vomiting Syndrome Epidemic Vomiting Epidemic Nausea Epidemic Viral Gastroenteritis Due To Norwalk Virus Noroviral Enteritis Crohn Disease Nos Crohns Cd - [Crohn'S Disease] Regional Enteritis Of Bowel Crohn'S Regional Enteritis Cobble-Stone Appearance Of Intestine Intestinal Ulcer And Erosion Due To Crohn Disease Granulomatous Enteritis
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Churg-Strauss Syndrome	Eosinophilic Granulomatosis With Polyangiitis Churg-Strauss Vasculitis Allergic Granulomatous Angiitis Allergic Angiitis Egpa Granulomatous Allergic Angiitis Allergic Granulomatosis Angiitis Allergic Angiitis And Granulomatosis Allergic Granulomatosis Allergic Granulomatous And Angiitis Css
Autoimmune Disease Of Central Nervous System
Mononeuritis Multiplex
Rhinitis	Runny Nose
Fungal Infectious Disease	Mycoses Mycosis
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Ige Responsiveness, Atopic	ATOPY Atopy, Susceptibility To Ige, Elevated Level Of IGER Immunoglobulin E, Basic Level Of, In Serum Ige, Level Of Igel Ige Response Underlying Allergic Asthma And Rhinitis Atopic Hypersensitivity Immediate Hypersensitivity
Urinary Schistosomiasis	Schistosoma Haematobium Infection Schistosoma Hematobium Infection Schistosomiasis Due To Schistosoma Haematobium Bladder Schistosomiasis Cystitis With Bilharziasis Schistosoma Haematobium Schistosoma Hematobium Infectious Disease Schistosomiasis Of Bladder Vesical Schistosomiasis Schistosomiasis Urinary Schistosomiasis Haematobia Genitourinary Bilharziasis Genitourinary Tract Schistosomiasis Schistosomiasis Due To Schistosoma Haematobium [Urinary Schistosomiasis] Haematochyluria In Schistosomiasis Infection Due To Schistosoma Matthei
Colitis
Volvulus Of Midgut	Intestinal Volvulus Volvulus Intestinal Malrotation, Familial Familial Intestinal Malrotation Twist Of Intestine, Bowel, Or Colon
Eosinophilic Fasciitis	Shulman Syndrome Ef Diffuse Fasciitis With Eosinophilia Eosinophilic Synovitis
Diabetes Mellitus	Diabetes
Otitis Media	Opsoclonus-Myoclonus Syndrome OMS Otitis Media, Susceptibility To Kinsbourne Syndrome Otitis Media, Chronic/Recurrent Come/Rom Ataxo-Opso-Myoclonus Syndrome Dancing Eye Syndrome Dancing Eye-Dancing Feet Syndrome Oma Syndrome Opsoclonus-Myoclonus-Ataxia Syndrome Poma Syndrome Paraneoplastic Opsoclonus-Myoclonus Paraneoplastic Opsoclonus-Myoclonus-Ataxia Syndrome Opsoclonus Myoclonus Syndrome Opsoclonus Myoclonus OM {Otitis Media, Susceptibility To} Infectious Otitis Media
Filarial Elephantiasis	Lymphatic Filariasis Elephantiasis Filariasis Bancroftian Elephantiasis Bancroftian Filarial Chyluria Elephantiasis Of Eyelid Bancroftian Filariasis Elephantitis Malayi Tropical Eosinphilia Wuchereria Bancrofti Infection Wuchereriasis Elephantiasis, Filarial Filarial Elephantiases Infection By Wuchereria Bancrofti Filarial Lymphangitis Tropical Elephantiasis Filarial Chylocele
T2-High Asthma	Type 2 High Endotype
Onchocerciasis	Infection By Onchocerca Volvulus River Blindness Onchocerca Volvulus Infection Volvulosis Robles' Disease Onchocerciasis, Ocular Robles Disease Onchocercosis Blinding Filariasis Robles Onchocerca Infestation Craw-Craw
Chronic Rhinitis	Rhinitis - Chronic Chronic Rhinitis Nos Rhinitis Rhinitis Nos
Diphtheria	Corynebacterium Infections Corynebacterium Infection Diphtherial Infection Infection Due To Corynebacterium Diphtheriae
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Food Allergy	Food Hypersensitivity Food Allergies Allergy Food Food Allergen-Induced Hypersensitivity
Chondroblastoma	Chondroblastoma Of Bone
Dyskinesia Of Esophagus	Esophageal Motility Disorders Dyskinesia Of Oesophagus Esophageal Dysmotility Esophageal Motility Disorder Oesophageal Dysmotility Oesophageal Motor Disorder Esophageal Spasm
Chronic Spontaneous Urticaria	Chronic Idiopathic Urticaria
Angiokeratoma Of Fordyce	Fordyce Angiokeratoma Fordyce'S Spot Fordyce-Type Angiokeratoma Of Scrotum
Keratoconjunctivitis
Conjunctivitis	Madras Eye Adenoviral Conjunctivitis Acute Adenoviral Follicular Conjunctivitis Inclusion Conjunctivitis Of The Adult Swimming-Pool Conjunctivitis Inflammation Of Conjunctiva Ophthalmia Acute Conjunctivitis Eye Catarrh Catarrhal Ophthalmia Koch-Weeks Conjunctivitis
Elephantiasis
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Mycosis Fungoides	Mycosis Fungoides Lymphoma Alibert-Bazin Syndrome Granuloma Fungoides Classic Mycosis Fungoides Mycosis Fungoides, Alibert-Bazin Type
Nasopharyngitis	Chronic Nasopharyngitis Chronic Rhinopharyngitis
Pulmonary Eosinophilia	Asthmatic Pulmonary Eosinophilia Eosinophilic Lung Infiltrate Weingarten'S Syndrome
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Papillary Conjunctivitis
Occupational Asthma
Physical Urticaria	Symptomatic Dermographism
Pemphigoid
Acute Asthma
Kimura Disease	Eosinophilic Lymphogranuloma Kimura'S Disease Eosinophilic Granuloma Of Soft Tissue Eosinophilic Hyperplastic Lymphogranuloma Eosinophilic Lymphofollicular Granuloma Eosinophilic Lymphofolliculosis
Chronic Urticaria	Urticaria Chronic Chronic Spontaneous Urticaria Chronic Ordinary Urticaria
Thunderstorm Triggered Asthma	Thunderstorm Asthma Thunderstorm Related Asthma
Angioedema	Angioneurotic Oedema Quincke'S Edema Angioneurotic Edema Giant Urticaria
Legume Allergy	Fabaceae Allergy
Trichinosis	Trichinellosis Human Trichinellosis Trichiniasis Trichinella Spiralis Infection Infection With Trichinella Trichinelliasis Trichinella Spiralis Infestation
Chlamydia	Chlamydial Infection Chlamydia Trachomatis Infectious Disease Chlamydial Disease Chlamydia Infections
Chromium Allergic Contact Dermatitis
Cutaneous Leishmaniasis	Diffuse Cutaneous Leishmaniasis Asian Desert Cutaneous Leishmaniasis Leishmaniasis, Cutaneous Leproid Leishmaniasis Leishmaniasis Diffuse Cutaneous Leishmaniasis Cutaneous Ethiopian Cutaneous Leishmaniasis Old World Cutaneous Leishmaniasis
Eosinophilia-Myalgia Syndrome	Eosinophilia Myalgia Syndrome Ems L-Tryptophan Induced Ems Severe Muscle Pain And Abnormally High Eosinophils Syndrome With Inflammatory And Autoimmune Components That Affect The Skin, Fascia, Muscle, Nerve, Blood Vessels, Lung, And Heart
Allergic Asthma	Atopic Asthma Extrinsic Asthma Extrinsic Asthma With Acute Exacerbation Extrinsic Asthma With Status Asthmaticus Asthma Allergic Atopic Asthma, Susceptibility To Ige-Mediated Allergic Asthma Allergen-Induced Asthma Allergic Asthma Without Stated Status Asthmaticus Predominantly Allergic Asthma Without Stated Status Asthmaticus Predominantly Allergic Asthma Allergic Asthma Nos Catarrh With Asthma Allergic Bronchitis Nos Extrinsic Allergic Asthma Predominantly Allergic Asthma With Stated Status Asthmaticus
Cholera	Vibrio Cholerae Infection Cholera - Vibrio Cholerae Cholera Due To Vibrio Cholerae Vibrio Cholerae Cholera Syndrome Asiatic Cholera Epidemic Cholera
Giant Papillary Conjunctivitis	Gpc Conjunctivitis Giant Papillary Conjunctivitis, Giant Papillary Chronic Giant Papillary Conjunctivitis Chronic Papillary Conjunctivitis
Urticaria	Nettle Rash Hives Wheal Urticaria Nos
Middle Ear Disease	Middle Ear Anomaly Disorder Of Middle Ear
Autoimmune Disease Of Skin And Connective Tissue
Peanut Allergy	Allergy To Peanuts Peanut Allergic Reaction Allergies Peanut Peanut Hypersensitivity
Angiostrongyliasis	A. Cantonensis Angiostrongyliasis
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Gastroesophageal Reflux	Gastroesophageal Reflux Disease Gerd GER Gastroesophageal Reflux, Pediatric Acid Reflux Gastresophageal Reflux Gastro-Esophageal Reflux Gerd - Gastro-Esophageal Reflux Disease
Norwegian Scabies	Crusted Scabies Seven Year Itch
Cysticercosis	Neurocysticercosis Submacular Cysticercosis Intestinal Taenia Solium Infection Pork Tapeworm Infection Tapeworm Infection: Intestinal Taenia Solum Tapeworm Infection: Pork Tenia Solium Infectious Disease Taeniasis Tenia Solium Infection Cysticerciasis Infection Due To Larval Form Of Taenia Solium
Cow Milk Allergy	Bos Taurus Milk Allergy Cow'S Milk Protein Sensitivity
Leprosy 3	Leprosy Leprosy, Susceptibility To, 3 Hansen'S Disease Leprosy, Susceptibility To Hansen Disease Infection Due To Mycobacterium Leprae LPRS3 Leprosy, Type 3 Anaesthesia Leprosy Anaesthetic Leprosy Maculoanaesthetic Leprosy Macular Leprosy Leprosy Unspecified
Disseminated Eosinophilic Collagen Disease
Radiculopathy	Pinched Nerve Nerve Root Disorder Radiculopathy, Site Unspecified Radicular Neuropathy Radicular Syndrome Radicular Pain Radiculitis Radiculitis Nos Spinal Root Pain Nerve Root Neuritis Radiculopathy In Spondylosis
Mite Infestation	Mite Infestations Acariasis Infestation By Mites Nos
Schistosomiasis	Katayama Fever Bilharzia Bilharziasis Schistosomiasis Mansoni Blood Fluke Schistosoma Mansoni Infection Snail Fever Acute Schistosomiasis Schistosomiasis Manson Schistosomiasis Due To Schistosoma Mansoni [Intestinal Schistosomiasis] Intestinal Schistosomiasis Nos Intestinal Schistosomiasis Egyptian Splenomegaly Bilharziasis Of Intestine Schistosomal Dysentery Schistosomiasis Of Colon Asiatic Schistosomiasis Eastern Schistosomiasis Schistosoma Japonicum Infection Schistosomiasis Japonicum Katayama Disease Katayama Syndrome Oriental Schistosomiasis
Bronchitis	Chronic Bronchitis Acute Bronchitis Bronchitis, Chronic Acute Bronchitis And Bronchiolitis Chest Cold Chest Infection Ci - Chest Infection Recurrent Wheezy Bronchitis Bronchitis Chronic Lower Respiratory Tract Infection Acute Lower Respiratory Tract Infection Chronic Bronchitis Nos Senile Bronchitis Bronchitis Nos In Those Under L5 Years Of Age Bronchitis Nos
Allergic Contact Dermatitis	Dermatitis, Allergic Contact Contact Dermatitis, Allergic Dermatitis Allergic Contact Allergic Contact Eczema Acd - [Allergic Contact Dermatitis] Allergic Contact Dermatitis, Unspecified Cause Allergic Dermatitis Allergic Eczema Allergy Dermatitis Allergy Eczema Allergic Contact Eczema Due To Clothing Or Footwear Perfume Allergic Contact Dermatitis Allergic Contact Dermatitis Due To Cosmetics Allergic Contact Eczema Due To Cosmetics Or Fragrances Allergic Contact Eczema Due To Dental Materials Allergic Contact Eczema Due To Food Flavours Or Additives Allergic Contact Eczema Due To Hairdressing Products Allergic Contact Eczema Due To Metals Or Metal Salts Allergic Contact Eczema Due To Proteins Allergic Contact Eczema Due To Plastics Or Resin Systems Allergic Contact Eczema Due To Preservatives Or Biocides Allergic Contact Eczema Due To Rubber Chemicals Rubber Dermatitis Allergic Contact Eczema Due To Systemic Medicaments Allergic Contact Eczema Due To Topical Medicaments Allergic Contact Dermatitis Due To Drugs In Contact With Skin
Persistent Severe Asthma
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Esophagitis	Acute Esophagitis
Ancylostomiasis	Ankylostomiasis Hookworm Infection Hookworm Infections Ancylostomiasis Due To Ancylostoma Duodenale Ancylostoma Duodenale Infection
Loeffler Endocarditis	Eosinophilic Endomyocardial Disease Eosinophilic Endocarditis Loeffler'S Endocarditis Primary Eosinophilic Endomyocardial Restrictive Cardiomyopathy
Allergic Disease	Hypersensitivity Allergic Hypersensitivity Disease Allergic Condition Allergic Reaction Allergic Disposition
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Cryptogenic Fibrosing Alveolitis Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Meningitis	Streptococcal Meningitis Acute Streptococcal Meningitis Staphylococcal Meningitis Adenoviral Meningitis Influenza Meningitis Influenzal Meningitis Meningitis Due To H. Influenzae Cryptococcal Meningitis Fungal Meningitis Due To Cryptococcus Neoformans Cryptococcosis Meningitis Cryptococcus Meningitis Cryptococcal Meningoencephalitis Meningitis Due To Cryptococcus Mumps Virus Meningitis Mumps Meningitis
Ulcerative Colitis	Colitis Gravis Left Sided Ulcerative Colitis Left-Sided Ulcerative Colitis Idiopathic Proctocolitis Inflammatory Bowel Disease, Ulcerative Colitis Type Uc Colitis Ulcerative Colitis, Ulcerative Chronic Left-Sided Ulcerative Colitis Uc - [Ulcerative Colitis] Chronic Ulcerative Enteritis Mucosal Proctocolitis Ulcerative Mucosal Proctocolitis Left Hemicolitis
Adenoid Hypertrophy	Hypertrophy Of Adenoids Adenoidal Hypertrophy Enlarged Adenoids Enlargement Of Adenoids Adenoidal Enlargement Adenoids, Hypertrophy Hypertrophy Of Adenoids Alone Adenoid Growth Hyperplasia Of Adenoids Hypertrophy Of Pharyngeal Tonsil
Respiratory Allergy	Airway Allergy
Rubella	German Measles Three Day Measles Rubella Nos
Intestinal Schistosomiasis	Schistosomiasis Japonica Schistosomiasis Mansoni Katayama Fever Schistosoma Japonicum Infection Schistosoma Mansoni Infectious Disease Schistosomiasis
Taeniasis	Beef Tapeworm Infection Infection By Taeniarhynchus Saginatus Taenia Saginata Infectious Disease Taenia Saginata Infection Pork Tapeworm Infection Armed Tapeworm Infection Infection By Taenia Solium Intestinal Taenia Solium Infection Pork Tapeworm Taenia Solium Taeniasis Adult Pork Tapeworm Infection Adult Pork Tapeworm Beef Tapeworm Infection By Taenia Saginata Unarmed Tapeworm Infection Taenia Saginata Taeniasis Infection Due To Adult Tapeworm Taenia Saginata Mediocanellata Taenia Infection Infestation By Taenia Saginata Infestation By Taenia Mediocanellata
Allergic Conjunctivitis	Conjunctivitis Allergic Conjunctivitis, Allergic Allergen-Induced Conjunctivitis Seasonal Allergic Conjunctivitis Perennial Allergic Conjunctivitis Spring Conjunctivitis Acute Allergic Conjunctivitis
Omenn Syndrome	Histiocytic Medullary Reticulosis Severe Combined Immunodeficiency With Hypereosinophilia Combined Immunodeficiency With Hypereosinophilia Reticuloendotheliosis, Familial, With Eosinophilia Reticuloendotheliosis Familial With Eosinophilia Familial Reticuloendotheliosis Omenn'S Syndrome OS Malignant Histiocytosis
Nasal Cavity Disease	Disorder Of Nasal Cavity
Cough Variant Asthma
Vasomotor Rhinitis	Rhinitis, Vasomotor Rhinitis Vasomotor Vmr - [Vasomotor Rhinitis]
Loeffler Syndrome	Loeffler'S Pneumonia Loffler'S Syndrome Simple Pulmonary Eosinophilia
Childhood-Onset Asthma	Childhood Asthma Asthma Childhood
Dermatitis, Atopic	Atopic Dermatitis Atopic Eczema Dermatitis, Atopic, Susceptibility To, 1 Atod Eczema, Atopic Dermatitis, Atopic 1 Allergic Dermatitis Atopic Neurodermatitis Besnier'S Prurigo Dermatitis, Atopic, 1 Dermatitis Atopic Eczema Besnier Prurigo
Silo Filler'S Disease	Silo Filler Disease Silo-Fillers' Disease
Opportunistic Mycosis	Opportunistic Mycoses Opportunistic Systemic Mycoses
Exercise-Induced Bronchoconstriction	Exercise-Induced Asthma Asthma Exercise-Induced
Scabies	Sarcoptic Itch Infestation By Sarcoptes Scabiei Infestation By Sarcoptes Scabiei Var Hominis Infestation By Sarcoptes Scabiei Var. Hominis
Proteasome-Associated Autoinflammatory Syndrome 1	Jmp Syndrome Nakajo-Nishimura Syndrome Nkjo Autoinflammation, Lipodystrophy, And Dermatosis Syndrome Proteasome-Associated Autoinflammatory Syndrome 1 And Digenic Forms Nakajo Syndrome PRAAS1 Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature Syndrome Candle Joint Contractures, Muscular Atrophy, Microcytic Anemia, And Panniculitis-Induced Lipodystrophy Aldd Joint Contractures - Muscle Atrophy - Microcytic Anemia - Panniculitis-Induced Lipodystrophy Nakajo Nishimura Syndrome Amyotrophy Fat Tissue Anomaly Japanese Autoinflammatory Syndrome With Lipodystrophy Jasl Joint Contractures Muscular Atrophy Microcytic Anemia And Panniculitis-Induced Lipodystrophy Nns Nodular Erythema With Digital Changes Secondary Hypertrophic Osteoperiostosis With Pernio Inflammation
Cellulitis
Mucocutaneous Leishmaniasis	American Cutaneous Leishmaniasis American Mucocutaneous Leishmaniasis Cutaneous Leishmaniasis, American Mucocutaneous Leishmaniasis, American New World Cutaneous Leishmaniasis Leishmaniasis, Mucocutaneous Espundia Leishmania Braziliensis Infection
Toxoplasmosis	Disseminated Toxoplasmosis Multisystemic Disseminated Toxoplasmosis Acquired Toxoplasmosis Toxoplasmosis Disease Or Disorder Infection By Toxoplasma Gondii Toxoplasmal Toxoplasma
Egg Allergy	Allergy To Eggs Allergies Egg Egg Hypersensitivity
Intrinsic Asthma	Non-Atopic Asthma
Filariasis	Disease Due To Superfamily Filarioidea Bancroftian Filarial Fever Mumu Wanganga Bancroftian Filariasis Wuchereriosis Brugiosis Malayan Filariasis
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Visceral Leishmaniasis	Kala-Azar Leishmaniasis, Visceral Infection By Visceral Leishmaniasis Leishmaniasis Visceral Sahib Disease Ponos Burdwan Fever Mard El Bicha Sirkari Disease Indian Visceral Leishmaniasis Dumdum Fever Visceral Leishmaniasis Due To Leishmania Donovani
Near-Fatal Asthma
Common Variable Immunodeficiency	Cvid Common Variable Agammaglobulinemia Acquired Hypogammaglobulinemia Common Variable Immune Deficiency Hypogamma-Globulinemia, Acquired Idiopathic Immunoglobulin Deficiency Primary Antibody Deficiency Primary Hypogammaglobulinemia Acquired Agammaglobulinemia Sporadic Hypogammaglobulinemia Common Variable Hypogamma-Globulinemia Immunoglobulin Deficiency, Late-Onset Common Variable Hypogammaglobulinemia Immunodeficiency, Common Variable
Hyper Ige Syndrome	Hyper-Ige Syndrome Hyper Immunoglobulin E Syndrome Hies Hyper-Ige Recurrent Infection Syndrome Hyperimmunoglobulin E Syndrome Hyper Ige Job Syndrome Hartnup Disease
Dermatitis	Eczema Skin Inflammation Inflammatory Dermatosis
Esophagitis, Eosinophilic, 1	Eosinophilic Esophagitis EOE1 Esophagitis, Eosinophilic Ee
Pneumonia	Acute Pneumonia Pneumonias Infectious Pneumonia Pn - [Pneumonia] Lobar Pneumonia Nos Multifocal Pneumonia Orthostatic Pneumonia Pneumonia Nos Chronic Pneumonia Nos Atypical Pneumonia Passive Pneumonia Purulent Pneumonia Interstitial Lobar Pneumonia Pneumonia, Unspecified Pneumonia Due To Chlamydia Pneumonia Due To Chlamydia Pneumoniae Pneumonia Due To E. Coli Escherichia Coli Lobar Pneumonia Pneumonia Due To H. Influenzae Pneumonia Due To Hemophilus Influenzae Bronchopneumonia Due To H. Influenzae Haemophilus Influenzae Lobar Pneumonia Bronchopneumonia Due To Hemophilus Influenzae Pseudomonal Pneumonia Pseudomonas Pneumonia Pseudomonas Lobar Pneumonia Staphylococcal Pneumonia Staphylococcus Pneumonia Acute Staphylococcal Pneumonia Staphylococcal Double Pneumonia Staphylococcal Lobar Pneumonia Staphylococcal Purulent Pneumonia Staphylococcal Bronchopneumonia Pneumococcal Pneumonia Pneumococcus Pneumonia Bronchopneumonia Due To S. Pneumoniae Pneumococcal Lobar Pneumonia Streptococcal Pneumoniae Pneumonia Streptococcus Pneumoniae Lobar Pneumonia Pyemic Pneumococcal Embolism With Pneumonia Bronchopneumonia Due To Streptococcus Pneumoniae Pneumonia Due To Streptococcus, Group B Group B Streptococcal Pneumonia Adenovirus Pneumonia Adenoviral Pneumonia Adenovirus Viral Pneumonia Pneumonia Respiratory Syncytial Viral Parainfluenza Viral Pneumonia Parainfluenzal Pneumonia Parainfluenza Virus Pneumonia Human Metapneumovirus Pneumonia Human Metapneumovirus Infection Resulting In Pneumonia Pneumocystis Pneumonia Plasma Cells Pneumonia
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Upper Respiratory Tract Disease
Contact Dermatitis	Contact Dermatitis/Eczema Contact Eczema Dermatitis Venenata Dermatitis, Venenata Dermatitis Contact Dermatitis, Contact
Scleritis
Mikulicz Disease	Igg4-Related Dacryoadenitis And Sialadenitis Mikulicz'S Disease Chronic Dacryoadenitis And Sialadenitis Mikulicz Syndrome Mikulicz' Disease
Parasitic Helminthiasis Infectious Disease	Helminthiasis Intestinal Helminthiasis Helminth Infection Helminthosis Worm Infection Worm Infections Helminth Infections Intestinal Infection Due To Class Cestoda And/Or Class Trematoda And/Or Phylum Nemata Parasitic Enteritis Metazoal Dysentery Intestinal Worms Nos
Granulomatosis With Polyangiitis	GPA Wegener Granulomatosis Wegener Granulomatosis, Formerly Midline Granulomatosis Wg, Formerly Necrotizing Respiratory Granulomatosis Wg Wegeners Granulomatosis Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis
Erythema Multiforme	Dermatostomatitis, Erythema Multiforme Type Em Erythema Multiforme Bullosum Erythema Polymorphe, Erythema Multiforme Type Febrile Mucocutaneous Syndrome Herpes Iris, Erythema Multiforme Type Stevens-Johnson Syndrome Em - [Erythema Multiforme]
Chronic Meningitis
Paracoccidioidomycosis	Mucocutaneous-Lymphangitic Paracoccidioidomycosis Paracoccidioidal Mycosis Lobo Disease Lutz-Splendore-Almeida Disease Pcm Paracoccidioidal Granuloma South American Blastomycosis Lobomycosis Brazilian Blastomycosis Lutz Disease Brazilian Blastomycotic South American Blastomyces Infection Paracoccidioides Brasiliensis Infection Paracoccidioidomycosis Unspecified
Cefuroxime Allergy	Cephuroxime Allergy Zinacef Allergy
Alveolar Echinococcosis	Echinococcus Multilocularis Infection Echinococcosis Alveolococcosis Multilocular Hydatid Small Fox Tapeworm
Eosinophilic Gastroenteritis	Eosinophilic Enteritis Ege Eosinophilic Gastroenterocolitis Eosinophilic Esophagitis Eosinophilic Gastritis Eosinophilic Gastroenteropathy Gastroenteritis, Eosinophilic Eosinophilic Enteropathy
Contact Blepharoconjunctivitis
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Disease Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Nut Allergy	Nut Allergic Reaction Nut Hypersensitivity Allergy To Nuts Allergy Nut
Commensal Bacterial Infectious Disease
Orange Allergy	Citrus Sinensis Fruit Allergy
Histiocytoid Hemangioma	Angiolymphoid Hyperplasia With Eosinophilia Epithelioid Haemangioma Epithelioid Hemangioma
Chronic Eosinophilic Pneumonia	Carrington Syndrome Idiopathic Chronic Eosinophilic Pneumonia Cryptogenic Pulmonary Eosinophilia Idiopathic Eosinophilic Chronic Pneumopathy Carrington'S Disease Carrington'S Pulmonary Eosinophilia Chronic Idiopathic Eosinophilic Pneumonia Eosinophilic Idiopathic Chronic Pneumopathy Eosinophilic Pneumonia Chronic
Vernal Keratoconjunctivitis	Vkc Spring Catarrh Keratoconjunctivitis Vernal Keratoconjunctivitis, Vernal
Leukocyte Disease	Leukocyte Disorders
Aztreonam Allergy	Azactam Allergy Primbactam Allergy
Hypereosinophilic Syndrome, Idiopathic	Idiopathic Hypereosinophilic Syndrome Hypereosinophilic Syndrome, Idiopathic, Resistant To Imatinib HES
Strongyloidiasis	Disseminated Strongyloidiasis Anguilluliasis Anguillulosis Infection By Strongyloides Threadworm Infection Enterobiasis
Diarrhea	Diarrhoea Diarrhea Of Presumed Infectious Origin
Chronic Eosinophilic Leukemia	Pdgfra-Associated Chronic Eosinophilic Leukemia
Environmental Induced Asthma	Irritant Asthma
Allergic Bronchopulmonary Aspergillosis	Aspergillosis, Allergic Bronchopulmonary Abpa Allergic Bronchopulmonary Mycosis Hinson-Pepys Disease Pulmonary Aspergillus Disease Allergic Aspergillosis Aspergillosis Allergic Bronchopulmonary
Necatoriasis	Miner'S Anaemia Negro Cachexia Dochmiasis Ground Itch Disease Brickmaker'S Chlorosis Coolie Itch Anaemia Cachexia Aquosa Dew Itch Anaemia Brickmaker'S Anaemia Tunnel Worker'S Anaemia Egyptian Anaemia Tunnel Worker'S Disease Miner'S Cachexia Greisinger Disease Tropical Chlorosis Egyptian Chlorosis Tunnel Anaemia Dochmiosis Necatorosis African Cachexia Water Itch Anaemia Infection Due To Necator Americanus St Gotthard Disease Gotthard Tunnel Disease
Yellow Fever	Urban Yellow Fever Jungle Yellow Fever Sylvatic Yellow Fever Yf Yellow Fever, Sylvan Bronze John Yellow Jack Yf- [Yellow Fever] Febris Flava
Dermatitis Herpetiformis	Duhring'S Disease Duhring-Brocq Disease Dermatosis Herpetiformis Brocq-Duhring Disease Dh Duhring Brocq Disease Dh - [Dermatitis Herpetiformis]
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Leishmaniasis	Post-Kala-Azar Dermal Leishmaniasis Post Kala-Azar Dermal Leishmaniasis Post-Kala-Azar Dermal Infectious Disease By Leishmaniasis Cutaneous Leishmaniasis Kala-Azar Visceral Leishmaniasis Leishmaniasis, Cutaneous Leishmaniasis, Visceral Leishmania Leishmania Infection Leishmaniosis
Parasitic Protozoa Infectious Disease	Protozoan Infections Mastigophora Infectious Disease Sarcomastigophora Infectious Disease
Lung Disease	Lung Diseases Disorder Of Lung Abnormality Of The Lung
Paragonimiasis	Infection By Paragonimus Lung Fluke Disease Lung Fluke Infection Pulmonary Paragonimiasis Paragonimus Westermani Infection Pulmonary Distomiasis Parasitic Haemoptysis Oriental Lung Fluke Disease Endemic Haemoptysis Paragonimosis Pulmonary Distomatosis Lung Fluke Disorder Infestation By Paragonimus Infection Due To Paragonimus Species Infestation Due To Paragonimus Species Oriental Lung Fluke Infestation Endemic Oriental Haemoptysis
Chronic Asthma
Igg4-Related Disease	Multifocal Fibrosclerosis Igg4-Related Sclerosing Disease Igg4-Related Systemic Disease Immunoglobulin G4-Related Sclerosing Disease Hyper-Igg4 Disease Igg4-Associated Disease Igg4-Positive Multiorgan Lymphoproliferative Syndrome Igg4-Related Autoimmune Disease Igg4-Related Systemic Sclerosing Disease Igg4-Syndrome Multifocal Idiopathic Fibrosclerosis Systemic Igg4-Related Plasmacytic Syndrome Systemic Igg4-Related Sclerosing Syndrome Mediastinal Fibrosis, Familial Retroperitoneal Fibrosis, Familial Igg4-Rd
Autoimmune Disease Of Gastrointestinal Tract
Skin Disease	Skin Diseases Abnormality Of The Skin Skin Diseases, Genetic Genodermatosis Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Sezary'S Disease	Sezary Syndrome Sézary Syndrome Sezary'S Lymphoma Sezary Disease Sezary Erythroderma Sezary Lymphoma
Loiasis	Mansonelliasis African Eye Worm Loa Loa Filariasis Mansonella Perstans Infections Mansonellosis Eye Worm Disease Of Africa Loa Loa Infestation African Eyeworm Disease Calabar Swelling
Aspirin-Induced Respiratory Disease	Aspirin-Sensitive Asthma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-17002	Suplatast (Tosilate)	Inhibitor	99.67%	Unkown

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9945	Mepolizumab		99.4%	Unkown
HY-P9923	Benralizumab		99.1%	Unkown
HY-P9949	Reslizumab	Antagonist	99.4%	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-111167	AN-2898	Inhibitor	/	Phase 2
HY-137131	DC-Chol hydrochloride		99.95%	Phase 1

Inhibitory Antibodies (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P9945A	Mepolizumab (anti-IL5)		97.50%	Phase 4
HY-P990748	Lunsekimig	Inhibitor	99.00%	Phase 3
HY-P99850	Depemokimab	Inhibitor	95.24%	Phase 3
HY-P99371	Lirentelimab	Inducer	99.91%	Phase 3
HY-P991599	SHR-1703	Inhibitor	/	Phase 3
HY-P991266	SM-17	Inhibitor	96.98%	Phase 2
HY-P991633	TQC2938	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (28)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19969	YM-90709	Inhibitor	99.77%	Unkown
HY-N6013	Aloin (mixture of A&B)		99.36%	Unkown
HY-NP159	House Dust Mite Extract, from D.farinae	Activator	/	Unkown
HY-N1938	D(+)-Raffinose pentahydrate		98.0%	Unkown
HY-N0646	Silydianin		99.71%	Unkown
HY-N8309	Luteolin-4'-O-glucoside	Inhibitor	99.36%	Unkown
HY-P1111	Lyn peptide inhibitor	Inhibitor	99.35%	Unkown
HY-110295	SPL-334	Inhibitor	99.6%	Unkown
HY-19486	UR-1505	Inhibitor	99.97%	Unkown
HY-147660	IMMH001	Agonist	98.10%	Unkown
HY-W585843	1,1′-Ethylidenebis[L-tryptophan]	Activator	96.04%	Unkown
HY-106979	Olcorolimus	Inhibitor	/	Unkown
HY-165484	AVP-13358	Inhibitor	/	Unkown
HY-175876	ADAM17-IN-1	Inhibitor	/	Unkown
HY-182795	Colchicine derivative-1		/	Unkown
HY-19472	RWJ-58643	Inhibitor	/	Unkown
HY-19472A	RWJ-58643 hydrochloride		/	Unkown
HY-P1111A	Lyn peptide inhibitor TFA	Inhibitor	/	Unkown
HY-RS06770	IL5 Human Pre-designed siRNA Set A		/	Unkown
HY-RS06771	Il5 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS06772	Il5 Rat Pre-designed siRNA Set A		/	Unkown
HY-RS06773	IL5RA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-169864	KRO-105714	Antagonist	/	Unkown
HY-174601	Human IL5RA mRNA		/	Unkown
HY-174602	Human IL5 mRNA		/	Unkown
HY-N6013R	Aloin (mixture of A&B) (Standard)		/	Unkown
HY-RS19696	Il5ra Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26191	Il5ra Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990774	Verekitug	Inhibitor	97.00%	Unkown
HY-P9923A	Benralizumab (anti-IL5RA )	Inducer	99.60%	Unkown
HY-P990213	Anti-Mouse/Human IL-5 Antibody (TRFK5)	Inhibitor	97.80%	Unkown
HY-P990094	Trabikibart		99.17%	Unkown
HY-P990058	Varokibart	Inhibitor	95.69%	Unkown
HY-P991144	Lasrekibart	Ligand	97.056%	Unkown
HY-P991712	Revbekitug	Inhibitor	96.18%	Unkown
HY-P992132	Solaprubart	Inhibitor	99.59%	Unkown
HY-P990452	Anti-IL-5 Antibody	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	IL5	VGNC	VGNC:41990
Mus musculus	IL5	MGD	MGI:96557
Rattus norvegicus	IL5	RGD	RGD:2900
Bos taurus	IL5	VGNC	VGNC:30164
Felis catus	IL5	VGNC	VGNC:102233
Others	IL5	NCBI