BDE30671203
BDE30671203 is a highly selective PLK1 inhibitor (IC50 = 2.163 nM). BDE30671203 induces G2/M phase arrest and Apoptosis. BDE30671203 downregulates key cell cycle regulators (CDC20, CDK1) and the anti-apoptotic gene Bcl-2. BDE30671203 exhibits anticancer activity against non-small cell lung cancer, large cell lung cancer, and liver cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C26H34N8O
- 분자량:474.60
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
PLK1 2.163 nM (IC50) |
PLK2 >10000 nM (IC50) |
PLK3 >10000 nM (IC50) |
CDK1 |
Bcl-2 |
Chemical Information
-
분자량 474.60
-
화학식 C26H34N8O
-
SMILES
O=C(N1CC(CC2=NC(N3CCN(C)CC3)=CC(NC4=CC(C)=NN4)=N2)CCC1)C5=CC=CC=C5
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BDE30671203 Related Classifications
HY-181030 Related Classifications
Powered by Bioz