1. Signaling Pathways
  2. Epigenetics
  3. PKC
  4. PKC Isoform
  5. PKC Activator

PKC Activator

PKC Activators (28):

Cat. No. Product Name Effect Purity
  • HY-18739
    Phorbol 12-myristate 13-acetate
    Activator 99.66%
    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator.
  • HY-13434
    Activator ≥99.0%
    Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus.
  • HY-13434A
    Ionomycin calcium
    Activator ≥98.0%
    Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus.
  • HY-18985
    Phorbol 12,13-dibutyrate
    Activator 98.78%
    Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator and a potent skin tumor promoter.
  • HY-12307
    (-)-Indolactam V
    Activator 99.30%
    (-)-Indolactam V is a PKC activator, with Kis of 3.36 nM, 1.03 μM for η-CRD2 (PKCη surrogate peptide), γ-CRD2 (PKCγ surrogate peptide), and Kds of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1B), and has antitumor activity.
  • HY-108355
    Activator ≥99.0%
    R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM.
  • HY-18981
    Activator 99.94%
    Decursin ((+)-Decursin) is a potent anti-tumor agent.
  • HY-12359
    Activator 99.81%
    TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11.9 nM.
  • HY-107613
    R 59-022
    Activator 99.82%
    R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM).
  • HY-N0699
    Activator 99.83%
    Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity.
  • HY-N0865
    Activator 98.17%
    Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
  • HY-131897
    Activator ≥98.0%
    1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids.
  • HY-N4322
    Decursinol angelate
    Activator 99.54%
    Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities.
  • HY-108391
    Activator ≥98.0%
    C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides.
  • HY-131648
    1-Oleoyl-2-acetyl-sn glycerol is a synthetic, cell permeable diacylglycerol analog.
  • HY-N2180
    Pinoresinol dimethyl ether
    Activator 99.39%
    Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furofuran lignan isolated from Magnolia biondii with neuritogenic activity.
  • HY-107613A
    R 59-022 hydrochloride
    Activator 98.88%
    R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 µM).
  • HY-107421
    Activator 99.32%
    Prostratin, a natural terpenoid compound, is a PKC activator, with a Ki of 12.5 nM and shows inhibitory effect on HIV-1.
  • HY-131897S
  • HY-128468
    1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol and a weak second messenger for the activation of PKC.