Antitumor agent-72
Antitumor agent-72 (compound 6w) is a potent anticancer agent. Antitumor agent-72 has anticancer activity and induces apoptosis through activation of caspase-3 and cleavage of PARP. Antitumor agent-72 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2676942-92-8
- Formula: C25H20ClNO6
- Molecular Weight:465.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Antitumor agent-72 (compound 6w) (0-10 µM; 72 h; BxPC3, PC3 and MCF7 cells) has anticancer activity and inhibits cell viability in a dose-dependent manner[1].
Antitumor agent-72 (compound 6w) (0-10 µM; 24 h; BxPC3 cells) induces apoptosis through activation of caspase-3 and cleavage of PARP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:BxPC3, PC3 and MCF7 cells
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Concentration:0, 0.03, 0.1, 0.3, 1, 3 and 10 µM
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Incubation Time:72 hours
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Result:Inhibited cell viability in BxPC3, PC3 and MCF7 cells with IC50 values of 0.47 µM, 2.68 µM and 1.82 µM, respectively.
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Cell Line:BxPC3 cells
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Concentration:0, 0.1, 0.3, 1, 3 and 10 µM
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Incubation Time:24 hours
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Result:Increased caspase-3 activation and PARP cleavage in BxPC3 cells.
Chemical Information
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CAS No. 2676942-92-8
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Molecular Weight 465.88
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Formula C25H20ClNO6
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SMILES
COC1=CC(O)=C(C(OC)=C1OC)C(C2=CC3=CC=CN3C(C(C4=CC=C(Cl)C=C4)=O)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-72 Related Classifications
HY-150696 Related Classifications
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