Cga - glycoprotein hormones, alpha subunit Gene

Also Known as HCG; LHA; FSHA; Tsha; aGSU; GPHA1; alphaSU; CG-alpha; GPHalpha; alphaGSU; alpha-GSU

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12640

Summary

Predicted to enable follicle-stimulating hormone activity. Acts upstream of or within several processes, including gonadotropin secretion; thyroid gland development; and thyroid hormone generation. Predicted to be located in extracellular region. Predicted to be part of follicle-stimulating hormone complex. Predicted to be active in extracellular space. Is expressed in brain; future pituitary; and retina nuclear layer. Orthologous to human CGA (glycoprotein Hormones, alpha polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Cga Products (1)

mRNA Protein Name
NM_009889.2 NP_034019.1 glycoprotein hormones alpha chain precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to hormone stimulus IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within developmental growth IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within follicle-stimulating hormone secretion IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within gonad development IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within luteinizing hormone secretion IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within negative regulation of organ growth IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of organ growth IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within thyroid gland development IMP
IMP: Inferred from mutant phenotype
12114718 MGI
acts upstream of or within thyroid hormone generation IMP
IMP: Inferred from mutant phenotype
12114718 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycoprotein hormones alpha chain

  • FSH-alpha

  • LSH-alpha

  • TSH-alpha

  • anterior pituitary glycoprotein hormones common subunit alpha

  • follicle-stimulating hormone alpha chain

  • follitropin alpha chain

  • luteinizing hormone alpha chain

  • lutropin alpha chain

  • thyroid-stimulating hormone alpha cha

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0621 Triclabendazole Inhibitor 99.36% Yes

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-148511 Vidutolimod 93.85% Phase 3
HY-13902 Berzosertib 99.67% Phase 2
HY-177338 STING agonist-45 Agonist 99.10% Phase 1

Pre-clinical Phase

Bioactive Molecules (117)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114180 RU.521 Inhibitor 99.95% Unkown
HY-131454 SR-717 Agonist 99.89% Unkown
HY-133916 G140 Inhibitor 99.17% Unkown
HY-128583 G150 Inhibitor 99.20% Unkown
HY-160225 ISD sodium 98.02% Unkown
HY-150741 ODN 2216 98.57% Unkown
HY-150724 ODN 1018 Agonist 99.28% Unkown
HY-150751 ODN TTAGGG 99.87% Unkown
HY-114182 PF-06928215 Inhibitor 99.68% Unkown
HY-P1680 Astin C Inhibitor 99.47% Unkown
HY-150751C ODN TTAGGG sodium Antagonist 93.80% Unkown
HY-W021040 Fludioxonil 99.94% Unkown
HY-172208 PROTAC cGAS degrader-1 Degrader 99.07% Unkown
HY-139056 SU0268 Inhibitor 99.96% Unkown
HY-160546 cGAS-IN-2 Inhibitor 99.67% Unkown
HY-150750 ODN M362 96.01% Unkown
HY-P5997 XQ2B Inhibitor 99.45% Unkown
HY-149526 cGAS-IN-1 Inhibitor 98.21% Unkown
HY-123230 Trifloxystrobin Inhibitor 99.49% Unkown
HY-164288 TDI-6570 Inhibitor 99.64% Unkown
HY-114181 IRAK4-IN-4 Inhibitor 99.55% Unkown
HY-170362 cGAS-IN-4 Inhibitor 99.28% Unkown
HY-131454A SR-717 free acid Agonist 99.36% Unkown
HY-124700 LYPLAL1-IN-1 99.9% Unkown
HY-174801 XL-3156 Inhibitor 99.91% Unkown
HY-B0821 Pymetrozine Inhibitor ≥99.0% Unkown
HY-116214 Cyprodinil 98.84% Unkown
HY-141831 STF-1084 Inhibitor 99.92% Unkown
HY-158045 PROTAC PARP1 degrader-1 Degrader 99.86% Unkown
HY-174802 XL-3158 Inhibitor 99.55% Unkown
HY-N2616 Vomicine Inhibitor 99.85% Unkown
HY-B1331 Cyromazine 99.79% Unkown
HY-170362A (R)-cGAS-IN-4 Control 99.94% Unkown
HY-171692 G3-YSD 98.37% Unkown
HY-RS02576 CGAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-149465 STF-1623 Inhibitor 99.90% Unkown
HY-132221 CU-32 Inhibitor 98.8% Unkown
HY-123230R Trifloxystrobin (Standard) Inhibitor 99.15% Unkown
HY-116214R Cyprodinil (Standard) 99.04% Unkown
HY-150742 ODN 2336 Agonist 90.74% Unkown
HY-150747 ODN 6016 Inducer 94.95% Unkown
HY-150748 ODN D-SL01 Agonist 99.94% Unkown
HY-160225F Biotin-labeled ISD sodium / Unkown
HY-RS02577 Cgas Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W411604 tert-Butyl hex-5-ynoate 98.0% Unkown
HY-118578 Furalaxyl Inhibitor 99.3% Unkown
HY-12464 Butafenacil 98.99% Unkown
HY-184095 Iptocigistat Inhibitor / Unkown
HY-115763 3-Aminopropylphosphinic acid Agonist / Unkown
HY-116214S Cyprodinil-d5 / Unkown
HY-116214S1 Cyprodinil-13C6 / Unkown
HY-123230S Trifloxystrobin-d6 Inhibitor / Unkown
HY-123230S1 Trifloxystrobin-d3 / Unkown
HY-13735H Quinacrine acetate / Unkown
HY-13902A Berzosertib hydrochloride 98.77% Unkown
HY-139678 SC13 / Unkown
HY-144328 STING agonist-10 Activator / Unkown
HY-144329 STING agonist-11 Activator / Unkown
HY-147129 cGAS-IN-9 Inhibitor / Unkown
HY-148412 Monarsen Inhibitor / Unkown
HY-150213 ODN BW001 Inhibitor / Unkown
HY-150751A Biotin-labeled ODN TTAGGG sodium / Unkown
HY-150751B FITC-labeled ODN TTAGGG sodium Antagonist / Unkown
HY-158126 G-quadruplex ligand 2 Inhibitor / Unkown
HY-159925 QKY-613 Activator 98.24% Unkown
HY-162459 cGAS-IN-3 Inhibitor / Unkown
HY-162944 NA-Ir / Unkown
HY-162966 MS7829 Activator / Unkown
HY-162967 MS8588 Degrader / Unkown
HY-163461 4F-DDC Inhibitor / Unkown
HY-169225 PDIC-NN Inducer / Unkown
HY-169225A PDIC-NN dimethanesulfonate / Unkown
HY-172218 Lenalidomide-hex-5-ynoic acid / Unkown
HY-175472 (GalNAc)3-CPT / Unkown
HY-176256 endo-S-cGAFMP Agonist / Unkown
HY-178032 PARP1-IN-44 / Unkown
HY-178431 MT-44 / Unkown
HY-179147 cGAS-IN-6 Inhibitor / Unkown
HY-179624 cGAS-IN-7 Inhibitor / Unkown
HY-180211 cGAS-IN-8 Inhibitor / Unkown
HY-180555 SN38-(PEG)2-Pom-α Activator / Unkown
HY-181850 Telomeric G4s ligand 2 / Unkown
HY-182360 Cytisine-platinum(IV) prodrug-1 / Unkown
HY-182758 Topoisomerase I-IN-21 / Unkown
HY-182926 Topoisomerase I/II-IN-9 Inhibitor / Unkown
HY-183748 Polθ-IN-11 / Unkown
HY-184398 cGAS/HDAC-IN-1 Inhibitor / Unkown
HY-184502 DDO-88109 Inhibitor / Unkown
HY-184662 Ferroptosis inducer-17 / Unkown
HY-187079 cGAS-IN-5-CH2-COOH Ligand / Unkown
HY-187080 cGAS-IN-5-CH2-amido-C9-NH2 / Unkown
HY-B0621S Triclabendazole-d3 / Unkown
HY-B0621S1 Triclabendazole-13C,d3 Inhibitor / Unkown
HY-B1331S1 Cyromazine-13C3 / Unkown
HY-N12507 Eupenicisirenin C Inhibitor / Unkown
HY-N15159 Cladophorol A Inhibitor / Unkown
HY-P3041 Chromostatin (bovine) Inhibitor / Unkown
HY-P3864 Pancreastatin (37-52), human Inhibitor / Unkown
HY-RS02575 CGA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02578 Cgas Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02624 CHGA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W020788 Benoxacor 99.39% Unkown
HY-114730 CGA-JK3 Inhibitor / Unkown
HY-121165 Cymiazole / Unkown
HY-165620 Etacelasil / Unkown
HY-RS17789 Cga Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18918 Chga Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24257 Cga Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W010319S 2-Amino-4-methoxy-6-methyl-1,3,5-triazine-d3 / Unkown
HY-W021040S Fludioxonil-13C3 / Unkown
HY-W289054S (S)-Metolachlor metabolite CGA 50720-d3 / Unkown
HY-W681867 Fluxofenim 98.03% Unkown
HY-W707416S N-(2,6-Dimethylphenyl)-N-(2-(methoxy-d3)acetyl)alanine / Unkown
HY-W714168S (rac)-Metolachlor metabolite CGA 351916-d3 / Unkown
HY-W714705S (S)-Metolachlor metabolite CGA 368208-d3 sodium salt / Unkown
HY-W722289S (rac)-Metolachlor metabolite CGA 50267-d3 / Unkown
HY-W751253 Dofenapyn / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990181 Anti-Mouse myeloperoxidase/MPO Antibody (6G4) Inhibitor 97.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cga NCBI NCBI:1081