MMP13 - matrix metallopeptidase 13 Gene

Also Known as CLG3; MDST; MANDP1; MMP-13

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 4322

About MMP13

Cytogenetic location: 11q22.2 Genomic coordinates (GRCh38): 11:102,942,995-102,955,732 (from NCBI)

This gene has 2 transcripts (splice variants), 203 orthologues, 23 paralogues and is associated with 7 phenotypes. Low expression observed in reference dataset.

Summary

This gene encodes a member of the peptidase M10 family of Matrix Metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II Collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

MMP13 Products (1)

mRNA	Protein	Name
NM_002427.4	NP_002418.1	collagenase 3 preproprotein

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	参考文献	由来
enables calcium ion binding	IDA IDA: Inferred from direct assay	23913860	GOA
enables collagen binding	IDA IDA: Inferred from direct assay	9065415	GOA
enables endopeptidase activity	IDA IDA: Inferred from direct assay	18164633	GOA
enables metalloendopeptidase activity	IDA IDA: Inferred from direct assay	8576151	GOA
enables zinc ion binding	IDA IDA: Inferred from direct assay	23913860	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in bone morphogenesis	IDA IDA: Inferred from direct assay	16167086	GOA
involved in collagen catabolic process	IDA IDA: Inferred from direct assay	8576151	GOA
involved in extracellular matrix disassembly	IMP IMP: Inferred from mutant phenotype	8576151	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MMP13 Protein Structure

PG_binding_1

Peptidase_M10

Hemopexin

0
100
200
300
400
471 a.a.

Protein Preferred Names	Protein Names
collagenase 3	matrix metalloproteinase 13 (collagenase 3)

MMP13 抗体

製品番号	製品名	アプリケーション	反応性
HY-P83398	MMP13 Antibody (YA3143)	WB	Human, Mouse
HY-P86592	MMP13 Antibody (YA6284)	WB, IHC-P, ICC/IF, ELISA	Human

関連疾患

Diseases	Alias
Exostosis	Osteophyte Orbital Exostosis Exostoses Exostosis Of Orbit Bone Spur Bony Outgrowth Swimmer'S Exostosis Osteophytes External Exotoses Cartilaginous Exostosis
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Cleidocranial Dysplasia	Cleidocranial Dysostosis CLCD Cleidocranial Dysplasia, Forme Fruste, Dental Anomalies Only Cleidocranial Dysplasia, Forme Fruste, With Brachydactyly CCD Marie-Sainton Disease Dysplasia Cleidocranial Dento-Osseous Dysplasia Marie-Sainton Syndrome Dysplasia, Cleidocranial
Osteochondrodysplasia	Chondrodystrophy Skeletal Dysplasia Congenital Anomaly Of Cartilage Osteochondrodysplasias Cartilage Development Disorder Osteochondrodysplasia Syndrome Dysplasia, Skeletal Mucopolysaccharidosis Iv
Type 1 Diabetes Mellitus 21	Diabetes Mellitus, Insulin-Dependent, 21 Iddm21 T1D21 Insulin-Dependent Diabetes Mellitus 21
Bone Disease	Bone Diseases Skeletal Disease Skeletal Disorder Disorder Of Skeletal System
Synovitis
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Coxa Vara
Tendinitis	Tendinopathy
Polyhydramnios
Septic Arthritis	Infectious Arthritis Arthritis, Infectious Arthritis Septic Arthritis, Bacterial
Spinal Stenosis	Lumbar Spinal Stenosis Cervical Spinal Stenosis Spinal Stenosis Of Lumbar Region Spinal Stenosis In Cervical Region Spinal Canal Stenosis
Spondyloepimetaphyseal Dysplasia	Dysplasia, Spondyloepimetaphyseal
Scoliosis
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Enchondromatosis, Multiple, Ollier Type	Ollier Disease Enchondromatosis Dyschondroplasia Osteochondromatosis Multiple Cartilaginous Enchondroses Multiple Enchondromatosis Enchondromatosis With Haemangiomata Enchondromatosis, Multiple Kast'S Syndrome Ollier'S Syndrome Enchondromatosis Multiple ENCHOM Maffucci Disease Olliers Disease Hereditary Multiple Exostoses Chondromatosis
Osteoarthritis	Osteoarthrosis Degenerative Joint Disease Hypertrophic Arthritis Arthropathy Degenerative Polyarthritis Degenerative Arthritis Osteoarthrosis And Allied Disorder Arthritis, Degenerative Oa Osteoarthritis Deformans Osteoarthrosis Deformans Kashin-Beck Disease
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Periapical Granuloma	Apical Granuloma
Chondrosarcoma	Cartilaginous Cancer Chondrosarcoma Of Bone Primary Chondrosarcoma Of The Bone CHDSA
Osteochondrosis	Osteochondritis Apophysitis Epiphysitis Osteochondritis Juvenilis Epiphyseal Necrosis Juvenile Osteochondrosis Of Tibial Tubercle
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Periapical Periodontitis	Apical Periodontitis Periodontitis Apical
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Bone Deterioration Disease
Metaphyseal Anadysplasia	Regressive Metaphyseal Dysplasia Early-Onset Regressive Form Of Metaphyseal Dysplasia Mad Maroteaux Verloes Stanescu Syndrome Maroteaux-Verloes-Stanescu Syndrome
Chronic Ulcer Of Skin	Chronic Wounds Callous Ulcer Indolent Ulcer Chronic Ulcer
Dental Caries	Dental Caries Extending Into Pulp Dental Caries Of Smooth Surface Dental Caries Pit And Fissure Smooth Surface Dental Caries Dental Decay Carious Teeth Dental Cavity Saprodontia Teeth Decayed Tooth Caries Tooth Decay
Aortic Aneurysm	Aortic Rupture Thoracoabdominal Aortic Aneurysm, Ruptured Ruptured Aortic Aneurysm Aortic Aneurysms Aortic Aneurysm Without Mention Of Rupture Nos Ruptured Abdominal Aortic Aneurysm Aortic Aneurysm, Ruptured Ruptured Thoracic Aortic Aneurysm
Metaphyseal Dysplasia, Spahr Type	Metaphyseal Chondrodysplasia, Spahr Type MDST Metaphyseal Chondrodysplasia Spahr Type Spahr Type Metaphyseal Chondrodysplasia Mcds Dysplasia, Metaphyseal, Spahr Type Metaphyseal Chondrodysplasia Schmid Type
Hyperostosis	Hypertrophy Of Bone Bone Hypertrophy Bone Thickening Periosteum Thickening
Malignant Peripheral Nerve Sheath Tumor	Mpnst Malignant Neurilemmoma Neurofibrosarcoma Malignant Neurofibroma Malignant Schwannoma Neurogenic Sarcoma Malignant Neoplasm Of The Peripheral Nerve Sheath Schwannoma, Malignant Malignant Peripheral Nerve Sheath Tumors
Aortic Aneurysm, Familial Abdominal, 1	Abdominal Aortic Aneurysm Aortic Aneurysm, Familial Abdominal 1 Aneurysm, Abdominal Aortic AAA Aortic Aneurysm, Abdominal AAA1 Aortic Aneurysm, Familial Abdominal Aortic Aneurysm Abdominal Abdominal Aortic Aneurysms Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture Abdomen Aneurysm Abdominal Aorta Aneurysm Aneurysm Of Abdominal Aorta Aortic Abdomen Aneurysm Aaa - [Abdominal Aortic Aneurysm] Abdominal Aneurysm Abdominal Aorta Aneurysm Rupture Abdominal Aorta Aneurysm Ruptured Abdominal Aortic Aneurysm Which Has Ruptured Ruptured Aaa Abdomen Aorta Aneurysm Ruptured Abdomen Aorta Rupture Abdomen Aortic Aneurysm Rupture Abdomen Aneurysm Rupture Abdomen Aortic Aneurysm Ruptured Abdomen Aortic Rupture Abdominal Aorta Rupture Abdominal Aortic Rupture Rupture Abdomen Aorta Aneurysm Rupture Abdominal Aortic Aneurysm Ruptured Abdomen Aneurysm Ruptured Abdomen Aorta Ruptured Abdomen Aortic Ruptured Abdominal Aneurysm Ruptured Abdominal Aorta Ruptured Abdominal Aortic Ruptured Aorta Abdominalis Aneurysm False Abdomen Aorta Aneurysm Ruptured False Abdominal Aortic Aneurysm Ruptured False Abdominal Aorta Aneurysm Ruptured False Abdomen Aortic Aneurysm Ruptured
Metaphyseal Dysplasia	Bakwin-Krida Syndrome Pyle'S Disease Pyle-Cohn Syndrome
Cartilage Disease	Cartilage Diseases Cartilage Disorder Chondropathy Cartilage Disorders Cartilage
Degenerative Disc Disease	Intervertebral Disc Degeneration Cervical Disc Degenerative Disorder Cervical Disc Degenerative Disease Lumbar Disc Degeneration Vertebral Disc Disease Degeneration Of Lumbar Intervertebral Disc Intervertebral Disc Disorder Discogenic Disease
Bone Structure Disease
Arthropathy	Ankylosis Of Ankle And Foot Joint Ankylosis Of Forearm Joint Ankylosis Of Hand Joint Ankylosis Of Joint Of Ankle And/Or Foot Ankylosis Of Joint Of Forearm Ankylosis Of Joint Of Hand Ankylosis Of Joint Of Lower Leg Ankylosis Of Joint Of Multiple Sites Ankylosis Of Joint Of Pelvic Region And Thigh Ankylosis Of Joint Of Shoulder Region Ankylosis Of Joint Of Upper Arm Ankylosis Of Lower Leg Joint Ankylosis Of Multiple Joints Ankylosis Of Upper Arm Joint Infectious Arthropathy Joint Ankylosis Of The Ankle And Foot Joint Ankylosis Of The Ankle And/Or Foot Joint Ankylosis Of The Forearm Joint Ankylosis Of The Hand Joint Ankylosis Of The Lower Leg Joint Ankylosis Of The Pelvic Region And Thigh Joint Ankylosis Of The Shoulder Region Joint Ankylosis Of The Upper Arm Joint Diseases Joint Disease Arthropathy Associated With Infection
Inguinal Hernia	Hernia Inguinal Hernia, Inguinal Inguinal Hernias Bubonocele Indirect Inguinal Hernia Direct Inguinal Hernia Oblique Inguinal Hernia Scrotal Hernia Ih - [Inguinal Hernia]
Periodontitis	Chronic Pericementitis Chronic Periodontitis
Spondylolisthesis	Slipped Vertebrae Acquired Spondylolisthesis
Basal Cell Carcinoma	Basal Cell Cancer Basal Cell Neoplasm Basal Cell Carcinoma Of Skin Malignant Basal Cell Tumor Basal Cell Tumor Epithelioma Basal Cell Malignant Basal Cell Neoplasm Rodent Ulcer Carcinoma Basal Cell Neoplasms, Basal Cell Basal Cell Carcinomas Experimental Organism Basal Cell Carcinoma Nodulo-Ulcerative Basal Cell Carcinoma Basalioma Basal Cell Epithelioma Of Skin Bcc - [Basal Cell Carcinoma] Of Skin Rodent Ulcer Of Skin Rodent Ulcer Of Unspecified Site Basal Cell Epithelioma Of Unspecified Site
Spondyloepimetaphyseal Dysplasia, Missouri Type	Metaphyseal Anadysplasia 1 Semd, Missouri Type Spondyloepimetaphyseal Dysplasia Type 2 SEMDM Spondyloepimetaphyseal Dysplasia Missouri Type Missouri Type Of Spondyloepimetaphyseal Dysplasia Semd Missouri Type Semd Type 2 MANDP1 Semd-Mo Spondyloepimetaphyseal Dysplasia Type Missouri Spondylometaepiphyseal Dysplasia Type Missouri Anadysplasia, Metaphyseal, Type 1
Osteochondritis Dissecans	Osteochondritis Ocd Konig Disease
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Plexiform Neurofibroma	Neurofibroma Plexiform Neurofibroma, Plexiform
Bone Inflammation Disease	Osteitis Bone Inflammatory Disease Inflammatory Disorder Of Bone
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

阻害性抗体 (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-P99590	Sotatercept		99.94%	Unkown

Clinical Phase

Bioactive Molecules (6)

製品番号	製品名	製品効果	純度	Phase
HY-12170	Prinomastat		98.41%	Phase 3
HY-12168	Tanomastat	Inhibitor	99.74%	Phase 3
HY-12270	T-5224	Inhibitor	99.59%	Phase 2
HY-100113	Buloxibutid		98.94%	Phase 2
HY-10398	CTS-1027	Inhibitor	99.24%	Phase 2
HY-112160	XL-784 free base	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (67)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-110397	KP-457	Inhibitor	98.88%	Unkown
HY-P4931	Mca-KPLGL-Dap(Dnp)-AR-NH2		99.30%	Unkown
HY-N1454	Apigenin-7-glucuronide	Inhibitor	99.74%	Unkown
HY-N1463	Luteolin 7-O-glucuronide	Inhibitor	99.98%	Unkown
HY-100359	CL-82198	Inhibitor	99.89%	Unkown
HY-12875	BQU57	Inhibitor	98.47%	Unkown
HY-107394	UK 356618	Inhibitor	98.91%	Unkown
HY-108672	NF157	Antagonist	99.13%	Unkown
HY-124029	BI-4394	Inhibitor	99.09%	Unkown
HY-N2350	Cynaropicrin	Inhibitor	99.79%	Unkown
HY-N1508	Ecliptasaponin A		99.81%	Unkown
HY-122624	MMP13-IN-2	Inhibitor	99.13%	Unkown
HY-19820A	NSC45586 sodium		98.0%	Unkown
HY-125166	DB04760	Inhibitor	99.18%	Unkown
HY-116302	MMP-9-IN-9	Inhibitor	99.26%	Unkown
HY-100518	T-26c	Inhibitor	99.52%	Unkown
HY-107639	UK-370106	Inhibitor	≥99.0%	Unkown
HY-128026	MMP-9/MMP-13 Inhibitor I	Inhibitor	99.68%	Unkown
HY-107428	PD-166793	Inhibitor	99.21%	Unkown
HY-117970	MMPI-1154	Inhibitor	99.76%	Unkown
HY-12093	MMP408	Inhibitor	99.04%	Unkown
HY-12170A	Prinomastat hydrochloride		98.53%	Unkown
HY-110397G	KP-457 (GMP)	Inhibitor	/	Unkown
HY-19485	XL-784	Inhibitor	98.25%	Unkown
HY-W011085	CP-471474	Inhibitor	99.2%	Unkown
HY-114091	PF-00356231 hydrochloride	Inhibitor	99.52%	Unkown
HY-147745	MMP2-IN-2	Inhibitor	98.80%	Unkown
HY-N2503	Ginsenoside F4		98.54%	Unkown
HY-P4905	Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2	Inhibitor	98.02%	Unkown
HY-110116	SD-2590 hydrochloride	Inhibitor	99.4%	Unkown
HY-P11800A	GPLGVRGC	Modulator	98.08%	Unkown
HY-100113A	Buloxibutid hydrochloride		/	Unkown
HY-100518A	T 26c sodium	Inhibitor	/	Unkown
HY-107013	CP-544439	Inhibitor	/	Unkown
HY-107640	WAY-170523	Inhibitor	/	Unkown
HY-110046	CL-82198 hydrochloride	Inhibitor	/	Unkown
HY-113621B	Ageladine A dihydrochloride	Inhibitor	/	Unkown
HY-114091A	PF-00356231	Inhibitor	/	Unkown
HY-114396	BR351	Inhibitor	/	Unkown
HY-119138	R-130823	Inhibitor	/	Unkown
HY-119185	AZD-6605		/	Unkown
HY-120505	ITZ-1	Inhibitor	/	Unkown
HY-12168B	(Rac)-Tanomastat	Inhibitor	/	Unkown
HY-12270S	T-5224-d8		/	Unkown
HY-14237	SC-77964	Inhibitor	/	Unkown
HY-149377	MMP13-IN-4	Inhibitor	/	Unkown
HY-149378	MMP13-IN-5	Inhibitor	/	Unkown
HY-153913	MMP-9-IN-7	Inhibitor	/	Unkown
HY-154868	MMP-13-IN-1	Inhibitor	/	Unkown
HY-181698	MMP13-IN-6	Inhibitor	/	Unkown
HY-P11641	GCRRGPLGLSLGKRRCG	Substrate	/	Unkown
HY-P11800	GPLGVRG		/	Unkown
HY-P2414	MMP-13 Substrate		/	Unkown
HY-P2414A	MMP-13 Substrate TFA		/	Unkown
HY-P3699	TNO003	Substrate	/	Unkown
HY-RS08525	MMP13 Human Pre-designed siRNA Set A		/	Unkown
HY-RS08526	Mmp13 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS08527	Mmp13 Rat Pre-designed siRNA Set A		/	Unkown
HY-100113R	Buloxibutid (Standard)		/	Unkown
HY-123438	WAY-151693	Inhibitor	/	Unkown
HY-129699	RH01617	Inhibitor	/	Unkown
HY-162902	ALK5-IN-82	Inhibitor	/	Unkown
HY-164525	SD-7300	Inhibitor	/	Unkown
HY-43586	BR351 precursor	Inhibitor	/	Unkown
HY-N13208	Stevia Powder		/	Unkown
HY-P3699A	TNO003 TFA	Substrate	/	Unkown
HY-W670700	2,5-Dihydroxy-4-methoxyacetophenone	Inhibitor	98.55%	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Mus musculus	MMP13	MGD	MGI:1340026
Macaca mulatta	MMP13	VGNC	VGNC:74891
Bos taurus	MMP13	VGNC	VGNC:31518
Rattus norvegicus	MMP13	RGD	RGD:620196
Canis familiaris	MMP13	VGNC	VGNC:43276
Felis catus	MMP13	VGNC	VGNC:68281
Others	MMP13	NCBI