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製品番号: HY-N16409

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Berkeleyamide C

Berkeleyamide C is a selective matrix metalloproteinase-3 (MMP-3) and caspase-1 inhibitor. Berkeleyamide C blocks MMP-3-mediated tumor cell invasion and metastasis, as well as the abnormal activation of inflammation and apoptosis related to caspase-1. Berkeleyamide C is promising for research of cancers and inflammation-related diseases.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1019854-23-9
分子式: C₂₂H₂₆N₂O₆
分子量:414.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Berkeleyamide C 構造式

CAS 番号: 1019854-23-9

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

IC₅₀ & Target

MMP-3

Caspase-1

MMP アイソフォーム固有の製品をすべて表示 :

Caspase アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]
HeLa	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]
HL-60	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]
K562	IC₅₀	>50 μM Compound: 7	Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 27359163]

化学情報

CAS 番号 1019854-23-9
分子量 414.45
分子式 C₂₂H₂₆N₂O₆
SMILES

CC(O[C@@H](C1=CC=CC=C1)C(N(C=C2C(NC(CC(C)C)=O)=O)CCO)=CC2=O)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Penicillium rubrum
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Stierle AA, et al. The berkeleyamides, amides from the acid lake fungus Penicillum rubrum. J Nat Prod. 2008 May;71(5):856-60. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

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Berkeleyamide C

MMP アイソフォーム固有の製品をすべて表示

Caspase アイソフォーム固有の製品をすべて表示