Deltamethrin-d6
Deltamethrin-d6 (Decamethrin-d6) is deuterium labeled Deltamethrin. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control.
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- CAS No.: 2483831-10-1
- 화학식: C22H13D6Br2NO3
- 분자량:511.24
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2483831-10-1
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Unlabeled Cas 52918-63-5
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분자량 511.24
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화학식 C22H13D6Br2NO3
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SMILES
N#C[C@H](C1=CC(OC2=CC=CC=C2)=CC=C1)OC([C@@H]3[C@@H](C3(C([2H])([2H])[2H])C([2H])([2H])[2H])/C=C(Br)\Br)=O
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Synonyms
Decamethrin-d6
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Lu Q, et al. Deltamethrin toxicity: A review of oxidative stress and metabolism [J]. Environmental research, 2019, 170: 260-281. [Content Brief]
[3]. Chi C C, et al. Effect of the pesticide, deltamethrin, on Ca2+ signaling and apoptosis in OC2 human oral cancer cells [J]. Drug and Chemical Toxicology, 2014, 37(1): 25-31. [Content Brief]
[4]. Kumar A, et al. Deltamethrin induced an apoptogenic signalling pathway in murine thymocytes: exploring the molecular mechanism [J]. Journal of Applied Toxicology, 2014, 34(12): 1303-1310. [Content Brief]
[5]. Rehman H, et al. The modulatory effect of deltamethrin on antioxidants in mice [J]. Clinica Chimica Acta, 2006, 369(1): 61-65. [Content Brief]
[6]. Hossain M M, et al. Neuromechanical effects of pyrethroids, allethrin, cyhalothrin and deltamethrin on the cholinergic processes in rat brain [J]. Life sciences, 2005, 77(7): 795-807 [Content Brief]
[7]. Yang X, et al. The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis [J]. Chemosphere, 2022, 300: 134479. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Deltamethrin-d6 Related Classifications
HY-B1971S1 Related Classifications
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