Copy Link Print Information

Pentamidine

(Synonyms: MP-601205)
9 Cited Publications
Kundenbewertung

Based on 9 publication(s) in Google Scholar

Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 97.19%
  • CAS. Nr.: 100-33-4
  • Formel: C19H24N4O2
  • Molecular Weight:340.42
  • Speicherung:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Pentamidine Chemical Structure
    Pentamidine Chemical Structure
  • Experimental Validation Results for Pentamidine
  • Experimental Validation Results for Pentamidine
  • Experimental Validation Results for Pentamidine
  • Experimental Validation Results for Pentamidine
  • Experimental Validation Results for Pentamidine
  • Experimental Validation Results for Pentamidine
CAS. Nr.: 100-33-4
Größe
Preis
Verfügbarkeit
Menge
Amount: USD 0.00
Please select quantity
or
or

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Pentamidine:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
  • Biologische Aktivität
  • Chemical Information
  • Lösungsmittel & Löslichkeit
  • Reinheit & Dokumentation
  • Verweise
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Pentamidine

More
Customer Validation & Images
Cell Proliferation/Viability AssayCell Migration/Invasion AssayWBIn Vivo Efficacy StudyRT-PCRIF
  • IF
  • Cell Proliferation/Viability Assay
  • Cell Migration/Invasion Assay
  • WB
  • RT-PCR
  • In Vivo Efficacy Study

Alle Parasite Isoform-spezifische Produkte anzeigen

More

Alle Antibiotic Isoform-spezifische Produkte anzeigen

More
Keywords
MOQ
Minimum order quantity
100 mg

Angebot einholen Auf Lager

Other size
Angebot einholen
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Einloggen
Registrieren
Sign in to MedChemExpress
Neuen Account Registrieren

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Pentamidine Chemical Structure
    Pentamidine Chemical Structure
    1/16
  • 1/16

    Pentamidine purchased from MedChemExpress. Usage Cited in: BMC Womens Health. 2022 Nov 24;22(1):470. [Abstract]

    Customer Validation
     Pentamidine (2.5, 5 μM; 24-36 h) reduces cell migration in a dose- and time-dependent manner, in Ishikawa and HEC-1A cells.

  • 1/16

    Pentamidine purchased from MedChemExpress. Usage Cited in: Drug Des Devel Ther. 2021 Jul 1;15:2857-2868. [Abstract]

    Customer Validation
     HO8910 cells were seeded in 96-well plates and treated with different concentrations of Pentamidine (0, 1, 2.5, 5.0, 7.5, 15, 20 μmol/L) for 24 hours, with three replicates for each concentration. Cell viability was then assessed after incubation with 20 μL of MTS for 1 hour.

  • 1/16

    Pentamidine purchased from MedChemExpress. Usage Cited in: Drug Des Devel Ther. 2021 Jul 1;15:2857-2868. [Abstract]

    Customer Validation
     Scratch healing experiments were performed using DMSO control and Pentamidin-treated HO8910 cells. Representative images were obtained at specified time points at a concentration of 2.5 μmol/L.

  • 1/16

    Pentamidine purchased from MedChemExpress. Usage Cited in: Drug Des Devel Ther. 2021 Jul 1;15:2857-2868. [Abstract]

    Customer Validation
     HO8910 and Caov3 cells were treated with different concentrations of Pentamidine (5/10/20 μM) for 24 hours. Cell lysates were collected and analyzed by Western blotting using anti-PTEN antibody. GAPDH was used as an internal control.

  • 1/16

    Pentamidine purchased from MedChemExpress. Usage Cited in: Drug Des Devel Ther. 2021 Jul 1;15:2857-2868. [Abstract]

    Customer Validation
     HO8910 and Caov3 cells were treated with 20 μmol/L Pentamidine for 24 hours. PTEN mRNA levels were detected by RT-PCR and normalized to 18S rRNA levels.

  • 1/16

    Pentamidine purchased from MedChemExpress. Usage Cited in: Molecules. 2020 Apr 23;25(8):1980. [Abstract]

    Customer Validation
     In vivo results for T. brucei mouse model of infection. Mouse survival after treatment with 30 mg/kg pentamidine (solid green line), 15 mg/kg Torin2 (solid black line), 5 mg/kg NVP-BGT226 (dotted black line), or the PBS control (solid blue line) for 5 days.

  • Pentamidine